TWAS hub - FADS1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1380	0.0320	2.8e-11	0.162	0.106	0.156	0.151	0.159	2.6e-19	7.2e-13	1.5e-18	5.9e-18	7.2e-19
2	GTEx	Artery Tibial	0.0866	0.0332	1.4e-03	-0.002	NA	0.008	NA	-0.002	4.9e-01	NA	7.0e-02	NA	4.6e-01
3	GTEx	Brain Cerebellum	0.3490	0.0870	3.5e-05	0.239	NA	0.296	NA	0.244	1.1e-07	NA	2.1e-09	NA	7.9e-08
4	GTEx	Brain Putamen basal ganglia	0.2920	0.0870	9.2e-04	0.213	NA	0.158	NA	0.139	8.5e-06	NA	1.4e-04	NA	3.7e-04
5	GTEx	Esophagus Mucosa	0.1090	0.0390	1.4e-03	0.000	NA	0.010	NA	0.019	3.0e-01	NA	6.1e-02	NA	1.9e-02
6	GTEx	Pancreas	0.1750	0.0530	1.1e-04	0.133	NA	0.110	NA	0.117	3.0e-06	NA	2.3e-05	NA	1.2e-05
7	ROSMAP	Brain Pre-frontal Cortex	0.0836	0.0232	7.5e-08	0.084	0.059	0.089	0.081	0.087	5.4e-11	4.9e-08	1.4e-11	1.4e-10	2.6e-11
8	YFS	Blood	0.1139	0.0256	0.0e+00	0.076	0.068	0.093	0.092	0.093	1.3e-23	2.2e-21	1.0e-28	1.5e-28	6.1e-29
9	TCGA	Breast Invasive Carcinoma	0.0364	0.0170	8.2e-04	0.001	0.012	0.002	NA	0.003	2.0e-01	1.4e-03	8.8e-02	NA	6.8e-02
10	TCGA	Cervical Squamous Cell Carcinoma	0.0600	0.0400	8.6e-03	0.032	0.028	0.035	NA	0.035	1.0e-02	1.6e-02	7.4e-03	NA	7.4e-03
11	TCGA	Kidney Renal Clear Cell Carcinoma	0.0991	0.0439	5.6e-03	0.010	0.018	0.009	NA	0.008	2.2e-02	3.3e-03	2.9e-02	NA	3.9e-02
12	TCGA	Brain Lower Grade Glioma	0.0515	0.0244	1.2e-05	0.046	0.035	0.008	NA	0.028	5.8e-06	6.8e-05	3.3e-02	NA	3.6e-04
13	TCGA	Liver Hepatocellular Carcinoma	0.1960	0.0880	5.6e-05	0.006	0.071	0.055	NA	0.027	1.6e-01	3.2e-04	1.3e-03	NA	2.0e-02
14	TCGA	Prostate Adenocarcinoma	0.0617	0.0323	1.5e-03	0.037	0.033	0.033	NA	0.028	8.3e-05	2.0e-04	2.2e-04	NA	5.9e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14
LDL Cholesterol	41.5	65.6	90.7	9.5	2.9	9.5	8.7	8.1	9.4	9.5	-7.4	6.7	8.6	2.9	9.3	9.5	7.1
Triglycerides	40.4	66.2	104.0	-10.0	-5.4	-9.5	-6.4	-8.5	-10.0	-10.2	7.4	-6.0	-9.5	-3.6	-7.9	-8.1	-8.4
HDL Cholesterol	38.9	64.9	94.9	9.7	4.5	9.7	7.9	8.4	9.5	9.6	-6.6	6.8	8.8	4.0	8.1	9.3	7.0
Pulse rate, automated reading	34.4	111.1	166.4	-12.8	-6.5	-12.1	-10.5	-12.9	-12.4	-12.8	8.7	-8.2	-10.2	-3.8	-11.0	-11.8	-9.4
Blood Platelet Count	28.1	325.4	479.6	-21.3	-12.5	-20.2	-16.3	-18.9	-21.9	-21.4	20.4	-13.0	-19.3	-7.2	-18.9	-18.2	-16.7
Fasting Glucose	24.1	28.9	46.1	6.3	2.9	6.5	4.0	5.9	6.6	6.5	-3.4	5.2	5.1	2.5	4.7	6.8	6.3
Pulse rate	20.9	35.3	55.3	-7.1	-3.6	-7.0	-6.1	-7.1	-6.8	-7.3	4.1	-4.9	-5.6	-1.7	-6.0	-7.4	-5.2
Blood Red Count	18.0	173.8	272.2	-16.3	-6.0	-15.9	-12.6	-13.6	-16.1	-16.5	13.3	-8.5	-14.4	-3.7	-13.9	-13.6	-12.5
Respiratory disease	16.0	35.5	55.4	7.3	3.6	6.7	4.8	5.6	7.4	7.1	-6.5	4.6	7.4	3.6	5.9	5.6	5.2
Asthma (self-reported)	14.0	27.8	43.7	6.5	3.6	6.0	4.7	4.7	6.5	6.3	-5.7	3.8	6.6	2.9	5.3	5.1	4.3
Average weekly champagne plus white wine intake	13.5	18.6	32.1	-5.7	-1.6	-4.8	-4.8	-4.4	-4.8	-5.4	4.0	-3.3	-4.7	-1.1	-4.8	-4.7	-3.6
Number of live births	13.2	18.7	28.3	5.0	2.0	4.9	3.0	3.8	5.3	5.1	-5.2	3.6	5.3	2.3	4.9	4.3	3.8
Asthma	12.8	25.3	39.9	6.2	3.4	5.8	4.5	4.3	6.2	6.0	-5.6	3.6	6.3	2.8	5.0	4.9	4.1
Blood Eosinophil Count	12.2	93.9	134.6	11.3	4.2	11.4	9.8	10.6	11.6	11.6	-9.0	7.3	10.6	2.5	10.3	10.3	9.8
Hypothyroidism (self reported)	11.6	26.7	42.8	6.2	3.4	5.8	4.3	5.7	6.2	6.5	-5.8	3.4	5.0	1.0	6.4	5.0	4.4
Medication: Levothyroxine sodium	10.5	17.8	29.4	5.2	3.8	4.7	3.0	4.9	5.0	5.4	-4.9	2.7	4.0	1.1	5.1	3.8	3.2
Crohns Disease (2012)	9.3	15.0	24.3	-4.9	-2.2	-4.8	-2.9	-4.8	-4.7	-4.8	3.8	-2.6	-4.2	-1.2	-3.8	-3.7	-3.7
Seen a psychiatrist for nerves, anxiety, tension or depression	8.9	11.5	16.5	-4.0	-0.6	-4.0	-3.2	-3.2	-3.9	-4.1	3.0	-3.5	-3.9	-2.0	-3.5	-3.9	-2.9
Blood White Count	8.7	64.4	100.0	8.8	4.5	9.1	7.3	9.3	10.0	9.5	-9.9	5.3	8.6	3.2	8.8	7.3	7.2
Medication: Simvastatin	8.6	12.6	19.3	4.1	0.7	4.1	3.9	2.5	3.8	3.8	-3.4	4.3	3.7	2.5	4.1	4.4	2.5
Hypothyroidism/myxoedema (self-reported)	8.3	16.2	27.8	4.9	2.5	4.5	2.7	4.8	4.8	5.0	-4.5	3.1	3.6	0.7	5.3	4.0	3.2
Heel bone mineral density (BMD) T-score, automated (right)	8.0	18.3	37.6	-4.8	-2.5	-4.7	-2.9	-4.1	-5.4	-5.0	6.1	-2.4	-5.3	-1.2	-4.1	-3.5	-4.8
Hair/balding pattern: Pattern 4	8.0	19.3	29.5	5.4	2.6	4.9	3.4	4.7	5.2	5.4	-4.7	3.3	4.8	1.7	4.6	5.1	3.9
Supplements: Fish oil (including cod liver oil)	8.0	10.4	17.6	4.0	2.0	3.8	2.2	4.0	3.8	4.2	-2.8	2.4	2.7	1.9	3.3	3.4	3.3
Irritability	7.9	13.4	22.1	-4.5	-2.7	-4.3	-3.7	-3.3	-4.3	-4.7	3.2	-2.3	-4.4	-0.9	-3.7	-3.7	-3.7
Deep venous thrombosis (DVT) (self-reported)	7.9	10.2	16.6	3.3	0.9	4.1	2.3	3.2	3.8	3.8	-2.6	3.9	3.0	2.3	3.3	3.6	3.1
Blood clot in the leg (DVT)	7.7	9.9	16.2	3.4	1.0	4.0	2.5	3.4	3.8	3.9	-2.8	3.4	2.9	1.9	3.4	3.4	3.0
Bipolar Disorder (2018)	7.5	11.9	21.9	-4.6	-1.1	-4.3	-4.7	-3.4	-3.7	-4.4	3.3	-2.2	-3.5	0.1	-4.2	-2.3	-2.9
Exposure to tobacco smoke at home	7.5	8.5	12.0	3.2	2.5	3.0	3.3	3.5	3.2	3.3	-3.1	2.1	2.4	2.1	2.7	3.2	2.4
High cholesterol (Self-reported)	7.4	13.2	19.3	4.2	0.9	4.3	4.4	2.5	3.9	3.9	-3.3	4.3	4.0	2.8	3.6	4.2	2.8
Wheeze or whistling in the chest in last year	7.2	12.9	19.4	4.3	3.4	4.4	3.4	3.9	4.1	4.4	-4.1	2.3	3.5	1.6	3.7	3.2	2.8
Crohns Disease (2017)	6.8	15.0	24.6	-5.0	-3.4	-4.9	-3.2	-4.8	-4.7	-4.9	3.8	-1.6	-4.3	-0.7	-4.1	-3.3	-2.8
Number of treatments/medications taken	6.8	12.2	22.9	4.0	2.2	4.2	2.2	3.1	4.0	4.2	-4.8	2.2	3.5	0.9	4.6	3.4	3.3
Allergy	6.7	15.3	24.7	-4.4	-5.0	-4.2	-2.0	-3.8	-4.8	-4.5	4.5	-2.9	-4.9	-3.3	-3.9	-2.6	-2.4
Qualifications: NVQ or HND or HNC or equivalent	6.6	7.9	11.6	3.4	2.8	3.1	2.7	3.0	3.1	3.4	-2.7	2.2	3.3	2.2	2.4	1.9	2.7
Commuting to job workplace: Car/motor vehicle	6.5	7.4	13.2	3.1	3.2	2.7	2.6	3.6	3.1	3.2	-2.9	2.1	2.0	0.5	2.6	2.6	2.5
Ever unenthusiastic/disinterested for a whole week	6.3	7.7	14.9	-3.6	-1.9	-3.7	-1.5	-3.0	-3.0	-3.3	2.6	-2.4	-2.5	-1.8	-2.9	-3.9	-1.0
Fractured/broken bones in last 5 years	6.2	8.0	13.5	3.1	1.8	2.9	3.5	2.8	3.3	3.4	-3.0	2.1	3.7	1.6	2.7	2.3	2.7
Schizophrenia vs Biploar Disorder	6.1	8.0	13.9	3.5	1.5	3.2	3.6	2.9	3.3	3.7	-2.6	1.3	3.1	-0.0	3.3	1.5	3.2
Type 2 Diabetes (T2D) (2012)	6.1	7.1	10.9	2.9	2.0	2.6	3.3	2.8	3.2	3.2	-2.4	1.5	3.1	0.4	3.1	2.7	2.3
Heel bone mineral density (BMD) T-score, automated (left)	6.1	13.9	28.0	-4.0	-1.7	-4.0	-2.9	-3.6	-4.6	-4.3	5.3	-2.3	-4.7	-0.7	-3.5	-3.0	-4.6
Myopia	6.1	8.9	17.5	-4.2	-1.0	-3.1	-3.1	-2.8	-3.4	-3.7	4.2	-1.4	-3.8	-0.9	-3.4	-2.1	-1.6
Bipolar Disorder (2011)	5.9	5.7	12.3	-3.2	-1.8	0.0	-2.7	0.0	-3.0	-3.3	3.0	-1.7	-2.6	-0.1	-3.5	-1.7	-2.3
Mineral and other dietary supplements	5.9	8.0	13.9	-3.3	-2.1	-3.7	-1.5	-3.7	-3.3	-3.5	2.5	-1.5	-2.3	-0.9	-2.8	-2.8	-3.5
Rheumatoid Arthritis	5.8	7.9	23.9	2.8	3.3	2.9	2.1	2.8	3.3	2.9	-4.9	0.2	2.7	-0.3	2.9	1.4	3.1
Heel T-Score	5.6	44.5	71.1	-8.2	-3.0	-7.6	-7.4	-6.8	-8.0	-8.4	6.7	-4.0	-7.4	-1.2	-6.6	-7.1	-6.5
Heart attack/myocardial infarction (self-reported)	5.6	7.2	14.5	3.0	2.5	3.0	3.8	3.5	2.8	3.0	-2.6	1.4	2.0	0.3	3.3	2.2	2.1
Cholesterol lowering medication	5.3	7.8	12.3	3.4	0.7	3.4	2.5	1.8	3.2	3.3	-2.6	2.6	3.5	1.0	3.3	3.1	2.9
Vitamin and mineral supplements	5.2	7.1	14.3	-3.3	-1.8	-2.9	-0.8	-3.1	-3.3	-3.2	2.6	-1.5	-3.4	-1.0	-2.4	-1.8	-3.8
Falls in the last year	5.2	7.0	11.2	3.4	2.5	2.5	2.5	3.0	2.9	3.2	-2.1	2.7	2.6	1.5	2.9	2.6	1.8
Taking other prescription medications	5.1	7.9	16.3	3.4	2.1	3.2	2.1	2.3	3.2	3.5	-4.0	1.4	3.1	0.5	3.7	2.2	2.2
Verbal and Numeric Reasoning (VNR)	5.0	12.1	22.2	-4.4	0.2	-3.4	-2.1	-4.1	-4.2	-4.2	4.7	-2.3	-3.6	-1.3	-4.1	-3.1	-3.5
Townsend deprivation index at recruitment	5.0	7.1	10.2	-2.8	-1.9	-3.0	-3.2	-3.0	-2.9	-3.1	2.2	-2.4	-2.3	-0.2	-3.2	-2.8	-2.7
Medication: Ibuprofen	5.0	6.0	9.5	2.9	1.9	3.0	1.6	2.2	2.9	3.1	-2.8	1.8	2.9	1.3	2.3	1.9	2.9
Forced expiratory volume in 1-second (FEV1), predicted	5.0	10.4	18.0	3.5	1.0	4.0	3.1	3.1	4.2	3.7	-3.7	1.5	3.8	1.1	2.3	3.4	4.1
Heart attack	4.7	6.1	14.6	2.7	2.3	2.8	3.8	3.1	2.5	2.7	-2.3	1.3	1.8	0.3	3.0	2.1	1.7
Number of self-reported non-cancer illnesses	4.7	8.1	14.6	3.3	2.2	3.0	2.2	2.8	3.3	3.4	-3.8	1.9	2.8	0.4	3.8	2.5	2.8
Medication: Allopurinol	4.6	6.1	19.4	-2.3	-4.4	-2.5	-1.9	-2.4	-2.8	-2.7	2.9	-1.0	-2.2	0.3	-3.1	-1.6	-2.1
Average weekly spirits intake	4.5	5.6	14.1	2.7	3.8	2.7	2.3	2.8	2.5	2.5	-2.1	1.5	1.9	0.2	2.3	2.2	1.7
Long-standing illness, disability or infirmity	4.5	6.9	13.6	3.0	2.0	2.8	2.8	2.1	2.9	3.1	-3.5	1.1	2.4	-0.6	3.7	2.4	2.4
Commuting to job workplace: Public transport	4.5	5.4	9.7	-2.6	-2.1	-2.1	-2.1	-3.0	-2.6	-2.6	1.8	-2.7	-1.8	-1.5	-1.9	-3.1	-1.9
Miserableness	4.3	7.5	11.6	-2.8	-0.7	-3.2	-2.7	-2.2	-3.4	-3.3	2.2	-2.8	-3.1	-2.0	-2.2	-3.0	-3.3
Family relationship satisfaction	4.1	5.1	10.4	-2.7	-1.6	-2.5	-2.3	-2.5	-2.2	-2.9	3.2	-0.0	-1.8	1.2	-3.1	-1.4	-1.9
Irritable Bowel Disease (IBD)	4.0	9.6	22.2	-3.8	-2.4	-4.7	-2.5	-3.9	-3.7	-4.0	2.2	-1.4	-3.1	-0.6	-3.2	-2.7	-2.3
Fluid intelligence score	4.0	8.4	16.9	-3.9	-0.5	-3.1	-1.1	-3.4	-3.6	-3.7	4.1	-0.6	-3.1	0.0	-3.7	-2.3	-2.6
Medication: Ibuprofen (e.g. Nurofen)	4.0	5.1	9.0	2.7	1.7	3.0	1.1	2.0	2.7	2.9	-2.7	1.5	2.8	1.4	2.0	1.5	2.5
Mouth/teeth dental problems: Mouth ulcers	4.0	6.3	14.6	-2.8	1.7	-2.6	-2.9	-1.9	-2.6	-2.5	1.0	-3.3	-2.5	-1.2	-2.4	-3.8	-2.6
Bipolar Disorder or Schizophrenia	3.9	9.5	18.0	-3.8	-0.5	-3.9	-4.2	-2.8	-3.2	-3.9	2.3	-2.8	-2.9	-0.3	-3.7	-3.1	-2.6
Standing height	3.9	38.2	55.2	7.0	3.1	7.4	6.9	6.9	7.4	6.9	-5.7	4.5	5.8	1.0	6.4	7.2	6.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.9	4.6	7.9	2.6	2.8	2.2	1.9	2.2	2.2	2.6	-2.2	0.9	2.0	-0.6	2.6	1.9	2.0
Other serious medical condition/disability diagnosed by doctor	3.8	4.9	11.3	2.2	1.7	1.9	2.6	2.0	2.4	2.6	-3.4	1.2	2.1	0.4	3.2	1.3	2.3
Osteoporosis (self-reported)	3.8	4.8	7.7	2.4	1.8	2.6	2.0	2.2	2.7	2.4	-2.8	1.4	2.5	1.2	2.1	2.1	1.9
Multivitamins +/- minerals	3.7	4.7	9.6	2.4	1.6	2.2	0.1	2.0	2.8	2.5	-2.2	1.6	3.0	2.1	1.6	1.4	3.1
Had other major operations	3.7	4.5	10.4	-2.4	0.1	-2.1	-1.5	-2.2	-2.6	-2.2	2.4	-2.1	-3.2	-1.5	-1.8	-2.2	-1.8
Seen doctor (GP) for nerves, anxiety, tension or depression	3.7	5.6	8.5	-2.9	-1.2	-2.9	-2.4	-2.4	-2.8	-2.9	2.8	-1.7	-2.6	-1.3	-2.3	-2.4	-1.6
Headache pain in last month	3.7	6.3	14.4	2.9	2.1	2.9	2.3	1.9	3.2	3.1	-3.8	0.8	3.2	1.1	2.1	1.2	2.4
Medication: Seretide 50 evohaler	3.7	4.3	7.8	2.4	1.1	2.4	2.1	1.8	2.5	2.2	-2.8	1.2	2.4	1.0	2.6	2.1	1.2
Major Depression (MDD)	3.6	4.4	13.1	-2.4	-3.6	-2.4	-1.7	-1.8	-2.2	-2.5	2.1	-0.9	-1.9	-1.0	-2.8	-1.5	-0.7
Height	3.5	66.8	100.0	9.0	3.2	9.5	8.2	8.2	9.8	9.1	-6.3	7.9	8.8	2.8	7.8	10.0	9.5
Hearing aid user	3.5	4.0	7.8	2.8	1.5	2.6	1.8	2.2	2.0	2.6	-2.4	1.1	1.3	-0.1	2.8	1.4	1.0
Intelligence (Savage-Jansen 2018)	3.4	10.5	21.4	-4.6	-0.5	-3.3	-2.2	-4.1	-4.0	-4.0	4.2	-1.3	-3.5	-0.7	-3.7	-2.6	-2.9
Exposure to tobacco smoke outside home	3.4	4.5	6.8	2.0	1.3	2.4	2.5	1.4	2.6	2.4	-2.0	2.2	2.2	2.5	1.6	2.3	1.9
Ever depressed for a whole week	3.4	4.2	9.7	-2.5	-1.9	-3.1	-0.9	-2.5	-2.2	-2.6	1.9	-0.9	-1.6	0.4	-2.7	-2.1	-1.2
Mouth/teeth dental problems: Bleeding gums	3.2	4.2	7.7	-2.8	-0.0	-2.5	-1.9	-2.2	-2.3	-2.5	2.3	-1.7	-1.6	-1.0	-2.1	-2.1	-2.0
Number of children fathered	3.2	3.6	9.3	2.1	0.9	2.2	1.0	2.2	2.2	1.9	-3.0	0.8	1.9	0.1	2.4	2.0	1.8
Maternal smoking around birth	3.1	4.4	11.5	2.3	1.2	1.9	2.2	1.7	2.6	2.0	-3.4	1.0	2.7	1.0	2.7	1.7	1.6
Tinnitus: Yes, but not now, but have in the past	3.1	3.3	8.0	2.0	2.8	1.8	1.9	2.2	2.0	2.0	-1.7	0.9	1.9	1.2	1.0	1.3	1.5
Gout (self-reported)	3.1	4.3	13.0	-2.0	-3.6	-1.9	-0.7	-2.0	-2.6	-2.3	3.1	-0.7	-2.0	-0.7	-2.2	-0.9	-1.4
Basal cell carcinoma (self-reported)	3.1	3.6	6.4	2.4	0.7	2.5	1.6	2.1	2.1	2.2	-1.9	0.5	2.4	-0.6	2.5	1.5	1.8
Hair/balding pattern: Pattern 3	3.0	4.5	8.2	2.5	1.5	2.1	2.6	2.7	2.2	2.3	-1.3	1.6	1.6	-0.0	2.7	2.9	1.9
Medication for pain relief, constipation, heartburn	3.0	5.2	10.5	-2.8	-1.8	-3.2	-1.5	-1.4	-2.4	-3.1	3.0	-0.7	-2.0	0.5	-3.0	-1.4	-2.8
Ovarian Cancer	2.9	3.8	6.6	1.8	0.5	2.6	2.6	1.5	2.1	1.9	-1.8	1.9	2.5	2.0	1.5	2.0	1.9
Had major operations	2.9	3.4	5.6	-2.2	-1.5	-1.9	-2.3	-2.4	-2.1	-2.4	0.8	-1.8	-1.5	-1.0	-1.6	-2.3	-1.1
Leg fat percentage (right)	2.7	9.9	16.8	-3.4	-4.1	-3.5	-1.6	-3.5	-3.7	-3.4	3.0	-2.5	-3.5	-2.5	-2.7	-3.1	-2.8
Medication: Cholesterol lowering	2.6	4.1	7.4	2.1	1.8	2.3	2.4	1.4	2.1	1.9	-2.0	2.0	2.0	0.9	2.6	2.7	1.4
Medication: Ventolin 100micrograms inhaler	2.6	3.4	5.5	2.2	0.9	2.3	1.5	1.4	2.3	2.0	-2.0	1.6	2.3	1.5	1.4	2.1	1.4
Supplements: Calcium	2.6	2.9	9.9	1.7	0.2	1.9	0.5	1.9	1.9	1.8	-1.7	1.3	1.5	0.3	1.9	1.5	3.1
Sitting height	2.4	17.2	26.8	4.8	2.5	4.8	4.8	4.8	4.7	4.5	-3.5	3.0	3.3	-0.0	5.2	5.2	3.6
Chronotype (morning person)	2.3	5.4	11.2	2.8	2.0	3.4	0.6	2.1	2.6	2.6	-2.3	1.8	2.4	1.4	2.0	2.9	2.4
Pulse wave reflection index	2.3	2.8	6.9	1.8	1.6	1.6	1.8	2.6	1.7	2.1	-0.6	1.3	0.7	-0.6	1.8	2.2	1.5
Worry too long after embarrassment	2.3	3.9	8.5	2.6	2.9	2.0	1.0	2.9	2.1	2.2	-2.4	-0.6	1.6	-1.0	2.1	0.7	1.5
Leg fat percentage (left)	2.3	8.3	15.5	-3.1	-3.9	-3.2	-1.2	-3.2	-3.4	-3.1	2.5	-2.3	-3.3	-2.3	-2.3	-2.9	-2.6
Diastolic blood pressure, automated reading	2.3	7.1	13.0	-3.6	-1.9	-3.4	-1.3	-3.3	-3.5	-3.1	2.4	-1.0	-3.3	-1.8	-1.9	-2.9	-1.9
HbA1C	2.2	2.4	4.5	2.0	0.8	1.7	1.5	1.6	2.1	2.1	-1.4	0.7	2.0	0.6	1.4	1.4	1.4
Medication: Paracetamol	2.2	3.4	6.9	2.4	1.3	1.6	1.7	1.8	2.0	2.6	-1.7	1.1	1.5	0.1	2.5	1.4	2.3
Medication for hormone replacement therapy	2.1	2.4	6.5	1.7	1.9	1.6	1.1	2.1	1.7	1.7	-2.5	-0.0	1.5	1.1	1.1	0.7	1.1
Hayfever/allergic rhinitis (self-reported)	2.1	2.7	4.9	1.8	1.1	2.2	0.6	1.9	2.2	1.9	-1.1	1.7	1.7	1.6	1.1	1.8	1.6
Forced expiratory volume in 1-second (FEV1)	2.1	7.1	13.5	2.9	2.5	3.5	1.4	3.3	3.5	3.0	-3.5	-0.3	2.6	-0.3	1.8	1.5	3.7
Medication: Lisinopril	2.1	2.7	5.2	-1.9	-1.4	-1.7	-1.5	-2.2	-1.8	-2.3	2.0	-0.8	-1.1	-0.1	-2.0	-1.2	-1.7
Lupus	2.0	3.0	7.1	2.2	0.2	1.6	1.9	1.6	2.3	2.1	-2.4	0.1	2.7	0.9	1.1	1.4	1.5
Ever highly irritable/argumentative for 2 days	2.0	2.4	4.1	-2.0	-1.2	-2.0	-0.5	-1.2	-1.7	-1.9	0.9	-1.2	-1.8	0.6	-2.0	-1.5	-1.9
Schizophrenia (2014)	1.9	4.2	7.4	-2.4	-0.7	-2.6	-2.7	-1.7	-2.0	-2.5	1.4	-2.1	-1.6	0.1	-2.5	-2.6	-1.6
Allergy or Eczema	1.9	4.9	10.1	2.4	3.2	2.0	0.5	1.9	2.7	2.4	-2.6	1.5	2.9	2.2	2.6	1.4	0.5
Body mass index (BMI)	1.9	8.2	13.8	-3.0	-3.7	-3.2	-0.8	-3.1	-3.5	-3.0	2.5	-2.1	-3.2	-1.6	-2.4	-3.1	-3.4
Leg pain on walking	1.9	2.4	5.1	1.4	-2.2	1.3	1.8	1.1	1.4	1.4	-1.6	0.4	1.8	-0.7	1.8	1.3	2.2
Eye problems/disorders: Cataract	1.9	2.2	3.4	1.7	1.5	1.5	1.6	1.8	1.6	1.8	-1.3	1.5	1.1	0.6	1.8	1.5	1.0
Ulcerative Colitis	1.8	2.6	6.0	-1.5	-0.8	-2.4	-1.6	-1.8	-2.0	-2.1	0.8	-1.2	-1.6	-0.3	-1.4	-1.6	-2.1
Mouth/teeth dental problems	1.8	2.8	6.9	2.0	0.1	2.0	1.4	2.4	1.9	1.8	-1.1	1.7	1.0	1.1	1.6	2.6	1.2
Arm fat percentage (right)	1.8	7.0	15.1	-3.0	-3.9	-2.8	-1.5	-2.9	-3.1	-2.9	1.9	-2.0	-3.1	-2.1	-2.2	-2.7	-2.2
Depression (self-reported)	1.8	2.1	10.5	-1.0	-1.3	-1.6	0.2	-0.7	-1.8	-1.5	0.1	-1.8	-1.1	-0.7	0.1	-1.8	-3.2
Medication: Paracetamol	1.8	3.0	5.6	2.2	1.4	1.7	1.4	1.6	1.9	2.4	-2.2	0.6	1.6	-0.2	2.1	1.1	2.2
Medication for cholesterol	1.8	2.7	5.8	-1.7	-2.3	-1.6	-1.4	-1.1	-1.8	-1.9	2.4	-0.4	-2.0	0.1	-1.7	-1.1	-2.0
Waist Hip Ratio (WHR)	1.7	7.7	16.9	3.0	1.4	3.4	2.5	3.1	3.2	2.9	-4.1	1.8	3.0	0.9	3.0	2.1	2.6
Qualifications: CSEs or equivalent	1.6	2.2	6.5	1.6	2.0	1.9	-0.1	1.9	1.7	1.5	-2.6	-0.4	1.3	1.2	0.3	0.5	1.0
Reason for reducing amount of alcohol drunk: Health precaution	1.6	1.8	4.0	-0.6	1.0	-1.5	-1.5	-0.9	-1.4	-1.0	1.3	-2.0	-1.3	-1.7	-0.8	-1.7	-1.7
Shortness of breath walking on level ground	1.6	1.9	3.5	1.3	0.2	1.2	1.5	1.2	1.6	1.4	-1.6	1.0	1.9	0.5	1.9	1.6	1.4
Wears glasses or contact lenses	1.6	1.9	4.6	-1.7	-0.4	-2.1	-1.4	-1.6	-1.5	-1.6	1.4	-0.5	-0.7	0.9	-1.1	-1.3	-1.6
Commuting to job workplace: Cycle	1.6	2.0	3.1	-1.8	-1.3	-1.2	-1.6	-1.7	-1.7	-1.6	0.7	-1.4	-1.5	-1.4	-0.9	-1.7	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.5	2.0	4.2	-1.2	0.7	-1.9	-1.6	-1.4	-1.7	-1.4	1.2	-0.7	-2.0	-0.2	-1.3	-1.6	-1.6
Hayfever, allergic rhinitis or eczema	1.5	3.2	11.2	1.9	3.3	1.6	-0.1	1.5	2.1	1.8	-2.1	0.9	2.4	1.9	1.8	0.7	0.3
Past tobacco smoking	1.5	2.8	6.3	-1.7	0.4	-1.9	-1.4	-1.6	-1.8	-1.8	1.0	-2.5	-0.8	-0.8	-2.4	-2.1	-1.6
Comparative height size at age 10	1.5	8.2	15.4	3.2	1.1	3.4	3.0	3.3	3.5	3.2	-2.3	2.2	2.3	-0.1	2.5	3.7	3.9
Father’s age at death	1.4	1.8	2.9	-1.7	-1.6	-1.4	-1.4	-1.4	-1.5	-1.7	0.5	-1.3	-1.4	-0.1	-1.3	-1.6	-1.2
Prospective memory result	1.4	1.7	3.9	1.6	0.6	1.6	0.4	2.0	1.6	1.6	-1.5	0.5	0.8	-0.7	1.3	1.2	1.5
Chronic bronchitis/emphysema (mother)	1.4	1.6	12.0	-0.8	0.5	-1.0	-0.9	-0.7	-1.1	-0.6	0.6	-1.5	-1.5	-3.5	0.1	-0.5	0.4
Medication: Aspirin	1.4	1.8	7.2	1.4	1.0	1.7	1.8	0.6	0.9	1.2	-1.4	-0.4	0.4	-1.6	2.7	0.6	0.9
Illnesses of father: High blood pressure	1.4	1.7	2.9	1.3	1.6	1.5	1.7	1.0	1.4	1.3	-1.0	0.9	1.6	0.7	0.9	1.4	1.5
Supplements: Glucosamine	1.3	1.7	3.1	1.6	1.7	1.7	0.3	1.7	1.5	1.6	-1.6	-0.1	1.3	0.7	1.0	0.8	1.0
Forced vital capacity (FVC)	1.3	5.0	12.2	2.4	1.7	3.0	0.6	2.7	3.1	2.5	-2.9	-0.3	2.2	-0.2	1.3	1.2	3.5
Mother’s age at death	1.3	1.6	3.2	-1.4	-1.2	-1.3	-1.8	-1.0	-1.3	-1.1	1.1	-1.0	-1.7	-0.9	-0.9	-1.5	-0.9
Age at First Birth	1.2	1.7	3.7	-1.9	0.7	-1.5	-0.2	-1.8	-1.6	-1.9	1.1	-0.2	-1.3	0.6	-1.6	-0.7	-1.5
Lung FVC	1.2	6.3	21.9	-2.1	1.0	-2.1	-4.7	-1.6	-2.0	-2.0	0.3	-3.7	-1.6	-0.8	-3.0	-4.2	-1.6
Chronic bronchitis/emphysema (father)	1.2	1.4	3.2	1.4	-0.3	1.3	0.1	0.3	1.6	1.4	-1.0	1.6	1.8	1.0	0.9	1.4	1.1
Medication: Ramipril	1.2	1.6	3.6	-1.5	0.5	-1.6	-1.9	-1.3	-1.6	-1.5	0.9	-0.8	-1.3	-0.5	-1.0	-1.1	-1.1
Body fat percentage	1.2	4.8	14.9	-2.4	-3.9	-2.0	-0.8	-2.3	-2.5	-2.2	1.6	-1.6	-2.7	-2.2	-1.6	-1.8	-1.4
Mean time to correctly identify matches	1.2	2.2	4.8	-1.3	-0.6	-1.8	-2.0	-0.8	-2.0	-1.3	2.2	-1.4	-1.6	-0.9	-1.7	-1.1	-1.3
Medication: Aspirin	1.2	1.6	6.7	1.1	1.2	1.5	1.6	0.5	0.5	0.9	-1.2	-0.8	-0.0	-2.1	2.6	0.5	0.6
Arm fat percentage (left)	1.2	4.9	12.8	-2.5	-3.6	-2.2	-0.9	-2.5	-2.6	-2.3	1.4	-1.6	-2.7	-1.7	-1.8	-2.2	-1.9
Type 2 Diabetes (T2D) (2018)	1.1	2.1	4.5	1.8	0.5	1.8	1.9	1.4	1.5	1.7	-1.2	1.1	0.7	-0.0	1.9	2.1	0.8
Angina	1.1	1.4	4.5	1.0	1.9	0.8	1.7	1.2	1.0	1.1	-1.8	0.1	0.2	-0.1	2.1	0.8	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.7	8.5	1.9	2.0	2.5	0.5	2.6	2.6	2.1	-2.4	-0.7	2.0	0.1	0.5	0.4	2.9
Overall health rating	1.1	2.4	4.7	1.4	2.2	1.3	1.5	1.4	1.7	1.8	-1.9	1.7	1.2	0.2	2.0	1.3	1.4
Chest pain or discomfort	1.1	1.6	2.8	1.1	1.5	1.5	1.5	0.7	1.2	1.1	-0.8	1.7	1.2	1.3	1.6	1.0	0.4
Smoking status: Previous	1.1	1.6	4.3	1.3	-0.1	1.5	0.4	1.0	1.4	1.3	-0.5	2.1	0.5	0.9	1.6	1.9	1.3
Commuting to job workplace: Walk	1.1	1.2	3.4	-0.9	0.1	-0.6	-1.8	-1.0	-1.2	-1.2	1.2	-1.1	-1.1	-0.4	-1.7	-0.9	-0.4
Alzheimer’s Disease (in father)	1.0	1.1	2.7	-1.2	-0.2	-1.6	-1.1	-1.2	-1.0	-1.2	0.2	-1.4	-0.5	-1.1	-0.8	-1.3	-0.7
Ulcerative Colitis (UC)	1.0	1.9	7.5	-1.3	-0.1	-2.7	-1.8	-1.5	-1.4	-1.9	-0.1	-0.8	-0.9	-0.0	-1.4	-1.3	-1.1
Stomach or abdominal pain in last month	1.0	1.3	5.1	1.2	2.3	1.2	1.5	0.9	1.1	1.1	-1.2	0.2	1.2	0.2	1.0	0.6	0.2
Impedance of arm (left)	1.0	4.8	16.3	1.6	1.6	3.1	-0.5	2.2	2.5	2.2	-2.4	1.9	1.3	0.2	1.9	2.3	4.0
Length of working week for main job	1.0	1.1	4.0	1.1	-0.8	0.8	1.4	1.6	1.2	1.3	-0.1	0.1	0.8	0.6	0.1	0.9	2.0
Eye problems/disorders: None of the above	1.0	1.1	2.4	-1.2	-1.1	-1.2	-1.5	-1.0	-1.1	-1.3	1.3	-0.3	-1.0	0.1	-1.4	-0.8	-0.6
Mouth/teeth dental problems: Loose teeth	1.0	1.2	4.4	-1.1	-1.5	-0.8	0.0	-1.0	-0.9	-1.1	2.1	0.5	-0.8	1.0	-1.3	-0.8	-1.3
Medication: Omeprazole	1.0	1.2	2.9	-1.2	-1.0	-1.0	-0.9	-1.4	-1.1	-0.9	-0.2	-1.5	-1.2	-1.2	-0.7	-1.7	-0.4
Leg fat mass (right)	1.0	3.9	11.5	-2.0	-3.4	-2.0	-0.0	-2.2	-2.2	-2.0	1.7	-1.5	-2.2	-1.6	-1.6	-1.8	-1.8
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	4.4	-1.5	-0.2	-1.0	-2.1	-1.0	-1.3	-1.7	0.9	0.3	-1.3	0.5	-1.0	-0.1	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	4.1	0.6	2.0	0.8	-0.5	0.8	1.3	0.6	-1.4	0.4	1.4	1.2	-0.5	-0.1	1.2
Ever smoked	1.0	1.8	4.6	1.1	-0.1	1.6	1.7	1.4	1.3	1.2	-0.8	2.1	0.4	1.0	1.8	1.6	0.8
Relative age of first facial hair	0.9	1.9	9.3	-1.4	0.6	-0.9	-0.7	-1.8	-1.2	-1.5	0.5	-1.7	-0.0	-3.0	-0.6	-1.7	0.2
Fed-up feelings	0.9	1.6	3.5	-1.1	-1.5	-1.9	-0.5	-1.2	-1.6	-1.3	0.7	-0.8	-1.8	-1.4	-0.6	-0.9	-1.5
Serious illness, injury or assault to yourself	0.9	1.1	2.3	1.1	1.1	0.9	1.5	0.2	1.2	1.4	-1.5	0.2	1.3	0.4	1.3	0.4	0.4
Medication: Atenolol	0.9	1.1	3.0	-1.1	0.2	-1.2	-0.4	-0.3	-1.5	-1.4	1.0	-1.0	-1.6	-0.4	-0.4	0.1	-1.7
Trunk fat-free mass	0.9	5.1	17.9	2.8	0.3	2.2	4.2	2.4	2.6	2.5	-2.0	1.1	2.2	0.5	2.2	2.4	1.1
Arm fat mass (right)	0.9	3.6	12.2	-1.9	-3.5	-1.9	0.0	-2.0	-2.1	-1.9	1.3	-1.3	-2.2	-1.7	-1.3	-1.7	-1.8
Angina (self-reported)	0.9	1.2	4.4	0.8	1.8	0.6	1.6	1.0	0.8	0.9	-1.8	-0.2	0.0	-0.5	2.1	0.6	-0.2
Pain type(s) experienced in last month: Hip pain	0.9	1.1	3.5	1.4	0.6	0.8	0.3	1.0	1.2	1.5	-1.4	0.4	0.8	0.5	0.5	0.5	1.9
Leg fat mass (left)	0.9	3.5	11.0	-1.9	-3.3	-1.9	0.2	-2.1	-2.1	-1.9	1.4	-1.4	-2.2	-1.6	-1.4	-1.7	-1.8
Schizophrenia (2018)	0.8	1.7	4.8	-1.2	0.3	-1.7	-1.7	-1.0	-1.2	-1.5	0.3	-1.8	-0.8	-0.4	-1.4	-2.2	-1.0
Alzheimer’s Disease (in mother)	0.8	1.0	2.5	1.2	1.4	0.9	1.0	0.2	0.7	0.8	-1.2	1.0	1.3	1.6	0.7	0.4	-0.0
Prostate Cancer	0.8	1.1	4.0	-0.7	2.0	-0.5	-0.8	-0.5	-0.6	-0.6	0.1	-1.9	-0.6	-1.7	-0.7	-1.5	-0.2
Primary Biliary Cirrhosis	0.8	1.1	7.4	-0.1	1.0	-0.6	-1.0	-0.5	-0.4	-0.4	-0.8	-2.7	-0.3	-0.9	-0.6	-1.4	-1.0
Lung FEV1/FVC ratio	0.8	4.2	6.0	2.3	1.8	2.2	2.1	2.5	2.4	2.3	-2.3	0.3	2.2	-0.5	2.5	1.9	1.8
Ever used hormone-replacement therapy (HRT)	0.8	1.1	2.5	1.5	-0.7	1.0	0.2	0.7	1.3	1.3	-1.6	0.6	1.3	0.5	1.0	0.8	1.1
High blood pressure	0.8	2.3	5.9	-1.9	0.1	-1.7	-1.7	-1.3	-2.0	-1.5	1.9	-0.4	-2.4	-1.5	-1.2	-1.2	-0.6
Happiness	0.8	1.0	3.7	-1.2	-0.7	-1.4	-0.9	-1.0	-0.7	-1.1	1.1	-0.2	-0.7	0.5	-1.9	-0.8	-0.1
Trunk predicted mass	0.8	4.9	17.3	2.7	0.3	2.1	4.2	2.4	2.5	2.4	-1.9	1.1	2.2	0.6	2.1	2.3	1.0
Qualifications: O levels/GCSEs or equivalent	0.8	1.2	3.1	-1.3	1.4	-0.7	-0.6	-0.1	-0.8	-1.2	0.8	-1.7	-0.2	0.2	-1.4	-1.5	-1.6
Migraine (self-reported)	0.8	1.0	2.5	0.7	1.3	0.5	-0.0	0.7	0.9	0.7	-1.3	1.5	1.4	1.6	0.4	0.4	0.5
Supplements: Vitamin C	0.8	1.0	4.0	1.2	-0.2	0.9	-0.3	0.9	1.2	1.0	-1.2	-0.1	1.4	-0.2	0.4	-0.0	2.0
Illnesses of father: Heart disease	0.8	1.1	3.7	1.0	1.2	1.0	1.9	1.3	1.0	1.1	-0.6	0.7	0.6	0.2	0.5	1.3	0.8
Friendships satisfaction	0.8	1.0	5.8	0.2	-0.1	0.7	0.3	-0.1	0.9	0.4	-0.2	2.1	1.0	2.4	0.1	1.3	0.5
Illnesses of father: None of the above (group 1)	0.8	1.0	3.2	-0.9	-0.6	-1.2	-0.6	0.1	-1.4	-1.1	0.9	-0.7	-1.6	-1.1	0.5	-0.3	-1.8
Medication: Omeprazole (e.g. Zanprol)	0.8	0.9	1.9	-1.1	-0.8	-1.0	-1.1	-1.1	-1.0	-0.9	0.4	-1.0	-1.2	-0.6	-0.8	-1.4	-0.4
Neuroticism (2016)	0.7	1.0	3.6	-0.6	-1.9	-1.1	-1.6	-0.5	-1.0	-1.0	0.1	-1.1	-0.9	-1.0	-0.2	-0.6	-0.8
Sensitivity / hurt feelings	0.7	1.2	2.2	1.2	0.9	1.0	0.8	1.1	1.2	1.3	-1.4	0.2	1.0	-0.5	1.2	1.2	1.5
Frequency of depressed mood in last 2 weeks	0.7	1.0	2.8	-0.9	-0.7	-1.5	-0.5	-0.9	-1.0	-1.1	0.8	-1.0	-1.1	0.1	-1.7	-1.3	-0.6
Supplements: Zinc	0.7	0.8	6.1	0.5	-2.5	0.9	-0.5	0.3	0.5	0.3	-0.5	-0.8	0.6	-0.7	0.3	0.1	1.1
Diabetes (mother)	0.7	0.9	2.8	0.9	1.1	0.7	0.3	0.3	1.1	1.0	-0.7	1.0	1.7	1.2	0.8	0.5	1.2
Severe depression (siblings)	0.7	0.7	4.6	-0.2	0.6	0.0	1.0	-0.6	0.2	0.0	-0.9	-1.4	0.6	-2.2	0.6	-0.0	0.8
Tense / ‘highly strung’	0.7	1.2	4.8	-1.1	2.0	-1.3	-2.2	-0.5	-0.6	-1.1	0.4	-0.7	-0.6	-0.1	-0.7	-1.1	-0.6
Forced vital capacity (FVC), Best measure	0.7	2.6	8.8	1.5	1.3	2.0	-0.2	2.1	2.3	1.7	-2.0	-0.6	1.7	0.3	0.0	0.1	3.0
Age at first live birth	0.7	1.3	5.3	0.7	1.6	1.5	0.9	0.8	1.1	0.7	-1.1	1.3	0.6	2.3	-0.2	0.8	0.8
Arm predicted mass (right)	0.7	3.6	17.1	2.3	-1.0	1.6	4.1	1.6	1.9	1.9	-1.3	1.1	1.8	0.6	1.8	2.0	0.5
Age at last live birth	0.7	1.0	3.5	0.8	1.3	1.9	0.2	1.4	1.1	0.9	-1.4	0.4	0.5	1.1	0.2	0.4	0.4
Whole body fat-free mass	0.7	4.0	18.4	2.4	-0.4	1.9	4.3	2.0	2.1	2.1	-1.7	1.1	1.7	0.4	1.9	2.1	0.7
Leg fat-free mass (right)	0.7	3.9	17.9	2.1	-0.4	2.1	4.2	1.9	2.0	2.0	-2.0	1.3	1.5	0.5	1.9	2.0	0.9
Whole body water mass	0.7	4.0	17.9	2.3	-0.5	1.9	4.2	1.9	2.1	2.0	-1.7	1.3	1.7	0.6	1.8	2.1	0.7
Leg predicted mass (right)	0.7	3.9	17.4	2.1	-0.5	2.0	4.2	1.9	2.0	2.0	-2.0	1.3	1.4	0.5	1.9	2.0	0.9
Arm fat mass (left)	0.7	2.7	9.4	-1.7	-3.1	-1.5	0.2	-1.8	-1.8	-1.6	0.9	-1.1	-2.0	-1.3	-1.1	-1.5	-1.6
Ever taken oral contraceptive pill	0.7	0.8	3.0	0.4	0.7	1.2	0.3	0.7	1.3	0.8	-1.0	0.0	1.1	0.3	-0.2	0.1	1.7
Average weekly beer plus cider intake	0.7	1.0	3.3	-1.0	-0.1	-1.3	-0.7	-0.4	-1.2	-0.8	1.8	0.0	-1.5	-0.9	-0.7	-0.2	-1.0
Vascular/heart problems diagnosed by doctor	0.7	1.8	4.8	1.6	-0.5	1.5	1.2	1.0	1.7	1.4	-1.4	0.6	2.2	1.7	0.9	1.0	0.7
Impedance of whole body	0.7	3.8	15.0	1.4	1.4	2.8	-0.7	1.9	2.2	1.9	-1.8	1.2	1.2	-0.5	1.7	2.0	3.9
Depression (Nagel 2018)	0.6	0.9	2.1	-0.8	-0.1	-1.4	-0.9	-0.8	-1.1	-1.0	0.9	-0.4	-1.0	0.4	-1.3	-1.2	-1.2
Hair Pigment	0.6	18.0	78.7	-4.5	-3.4	-4.1	-3.5	-4.3	-4.7	-4.4	8.9	-0.1	-3.9	-1.3	-5.5	-1.6	-1.7
Medication: Co-codamol	0.6	0.7	1.9	0.8	-0.3	0.6	0.4	0.6	1.0	0.6	-1.4	-0.0	1.3	1.4	-0.4	0.4	0.7
Medication: Metformin	0.6	0.9	3.7	-0.8	-1.9	-0.5	0.4	-1.2	-1.0	-0.7	1.0	-0.3	-0.9	-1.3	0.0	-0.8	-0.9
Trunk fat percentage	0.6	2.5	12.5	-1.5	-3.5	-1.1	-0.2	-1.6	-1.7	-1.4	1.0	-0.7	-2.1	-1.9	-0.8	-0.8	-0.7
Qualifications: None of the above	0.6	1.3	4.7	0.7	-2.2	0.1	-0.8	0.1	0.1	0.5	0.5	1.9	-0.1	-1.2	1.5	2.1	0.9
Alcohol intake versus 10 years previously	0.6	0.9	2.6	1.0	-1.0	1.3	1.3	0.7	0.4	0.7	-0.2	1.6	0.3	0.4	1.1	1.3	0.7
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	3.7	-1.0	-0.7	-0.9	-1.0	-1.0	-0.8	-0.7	0.4	-1.5	-0.2	-0.2	-1.3	-1.9	-0.5
Medication: Amlodipine	0.6	0.9	2.7	-0.8	0.5	-0.7	-1.2	-0.7	-0.9	-0.7	0.0	-1.6	-0.8	-0.3	-0.7	-1.2	-1.5
Arm fat-free mass (right)	0.6	3.2	16.9	2.1	-1.5	1.5	4.1	1.5	1.6	1.7	-0.9	1.2	1.3	0.6	1.7	2.0	0.3
Pulse wave peak to peak time	0.6	0.8	1.8	1.1	-0.9	1.0	-0.1	0.6	1.2	0.8	-0.4	0.4	1.3	1.0	0.1	0.8	1.1
Suffer from ‘nerves’	0.6	0.9	4.6	-0.0	-0.6	-0.1	1.0	0.4	0.6	0.2	-1.3	1.5	0.4	2.1	0.2	0.8	1.2
Back pain experienced in last month	0.6	0.9	2.1	1.0	-0.8	1.1	0.7	0.4	0.9	1.0	-1.0	0.9	0.8	1.2	0.0	1.3	1.4
Financial situation satisfaction	0.6	0.7	1.7	1.1	-0.1	1.1	1.0	0.3	1.1	1.0	-1.3	-0.8	1.0	-0.5	0.5	-0.2	0.5
Eye problems/disorders: Glaucoma	0.6	0.7	3.8	0.4	-0.4	0.3	-0.5	-0.8	0.5	0.3	0.5	1.4	1.2	2.0	-0.5	1.1	-0.0
Age started oral contraceptive pill	0.6	0.8	2.6	-0.3	-1.4	-0.9	-0.3	-0.6	-1.0	-0.7	0.8	0.8	-1.2	0.4	0.5	-0.3	-1.6
Unable to work because of sickness or disability	0.6	0.8	7.1	0.2	-0.1	0.0	0.3	0.5	-0.6	0.1	-0.4	-1.0	-1.1	-2.7	1.0	-0.2	-0.4
Depressed Affect (Nagel 2018)	0.5	1.2	2.9	-0.9	-0.1	-1.6	-0.9	-0.4	-1.6	-1.2	0.8	-0.7	-1.7	-0.5	-0.3	-0.7	-1.7
Mean Putamen Volume	0.5	0.6	2.8	-0.5	-1.7	-0.5	-0.3	-1.2	-0.7	-0.5	0.5	-0.3	-0.3	-0.1	-1.1	-1.3	0.0
BMI	0.5	3.0	6.3	-1.7	-2.5	-2.1	0.4	-1.8	-1.8	-1.7	0.5	-1.7	-1.4	-1.0	-1.1	-2.4	-2.3
Systolic Blood Pressure	0.5	2.4	5.7	1.1	1.8	0.7	2.0	2.0	1.2	1.5	-1.3	2.4	0.5	1.4	1.5	1.7	1.1
Hearing difficulty/problems: Yes	0.5	0.8	2.7	0.3	1.3	-0.8	-0.6	0.2	-1.0	-0.1	0.5	-0.5	-0.9	-1.6	1.2	-0.6	-1.3
Diabetes (father)	0.5	0.6	1.3	1.1	0.1	1.1	0.6	0.2	1.0	1.0	-0.7	0.2	1.1	-0.7	0.6	0.8	0.7
Leg fat-free mass (left)	0.5	2.7	14.5	1.7	-1.0	1.7	3.8	1.5	1.6	1.6	-1.4	1.1	1.1	0.3	1.5	1.7	0.6
High blood pressure (mother)	0.5	0.7	1.6	0.7	1.0	1.0	1.1	0.6	0.8	0.9	-0.5	0.4	0.9	-0.4	0.9	1.0	1.3
Leg predicted mass (left)	0.5	2.8	14.8	1.8	-0.9	1.7	3.8	1.5	1.6	1.6	-1.4	1.2	1.1	0.3	1.5	1.7	0.7
Illnesses of siblings	0.5	0.6	2.0	0.7	1.4	1.0	0.5	1.1	0.8	0.8	-0.6	-1.2	-0.0	-0.5	0.2	-0.2	0.8
Neuroticism score	0.5	1.1	2.9	-1.2	0.3	-1.7	-1.3	-0.5	-1.1	-1.4	-0.1	-1.1	-1.3	-0.4	-0.8	-1.4	-0.8
Impedance of arm (right)	0.5	2.4	11.2	0.8	1.2	2.1	-1.4	1.5	1.6	1.3	-1.5	1.2	0.7	-0.4	1.0	1.4	3.3
Qualifications: A levels/AS levels or equivalent	0.5	1.0	5.6	-0.2	2.4	0.3	0.1	-0.0	0.3	0.1	-1.2	-1.2	0.8	1.2	-0.7	-1.2	-1.1
Lung cancer (father)	0.5	0.6	2.5	-0.4	-0.7	-0.6	-0.2	0.0	-0.7	-0.3	1.6	1.1	-1.4	0.0	0.7	0.5	-0.5
Pulse wave Arterial Stiffness index	0.5	0.6	1.5	-0.9	1.1	-0.8	0.5	-0.2	-0.9	-0.5	0.1	-0.3	-1.2	-1.0	0.1	-0.5	-0.9
Birth weight	0.5	1.2	3.3	-0.8	-1.8	-1.3	0.2	-0.4	-0.5	-1.0	1.5	1.6	-0.5	1.5	-0.9	-0.1	-1.1
Comparative body size at age 10	0.5	1.4	4.5	-0.7	-1.1	-1.6	1.1	-0.5	-1.1	-0.8	-0.0	-1.4	-0.8	-1.6	-0.3	-2.1	-1.2
Qualifications: College or University degree	0.5	1.5	7.4	-0.9	2.7	-0.4	-0.2	-0.5	-0.5	-0.7	0.1	-2.3	-0.8	-0.3	-1.0	-1.6	-1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.9	-0.3	-1.1	0.1	1.2	0.2	-0.4	-0.4	0.3	0.9	-0.8	-0.3	0.8	1.4	-0.8
Whole body fat mass	0.5	2.3	10.4	-1.3	-3.2	-1.1	0.6	-1.5	-1.5	-1.3	0.9	-1.1	-1.8	-1.9	-0.8	-1.0	-1.1
Number of full sisters	0.5	0.6	2.3	-0.8	-1.2	-0.9	-0.5	-1.5	-0.5	-0.9	0.1	-0.4	-0.0	-0.5	-0.3	-0.7	-0.7
Hypertension (Self-reported)	0.5	1.3	3.5	-1.4	0.5	-1.2	-1.3	-1.0	-1.5	-1.1	1.1	-0.6	-1.9	-1.5	-0.7	-1.0	-0.2
Mood swings	0.5	0.8	1.7	-0.8	-0.8	-0.9	-1.1	-0.5	-1.1	-0.9	1.1	-0.6	-1.3	-0.9	-0.6	-0.9	-1.1
Diabetes diagnosed by doctor	0.5	0.8	2.8	0.9	-0.7	1.0	1.4	0.2	0.6	0.8	-0.5	0.5	0.3	-0.5	1.7	1.2	0.0
Qualifications: nursing, teaching	0.5	0.8	2.9	-1.1	1.0	-0.7	0.6	-0.8	-0.6	-0.6	0.8	-1.7	-0.6	-1.1	-1.0	-1.1	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.1	5.2	-0.4	0.9	-0.4	-1.5	0.0	-0.5	-0.4	-0.3	-2.3	-0.7	-1.3	-1.3	-1.7	-0.1
Medication: Blood pressure	0.5	0.9	2.1	-1.1	1.2	-1.0	-1.1	-1.4	-0.8	-0.9	-0.2	-0.8	-0.8	-0.8	-0.8	-1.0	0.0
Basal metabolic rate	0.5	2.8	15.1	1.9	-0.9	1.6	3.9	1.6	1.6	1.6	-1.4	0.8	1.2	0.0	1.6	1.7	0.6
Body Mass Index (BMI) (2010)	0.4	0.6	3.3	-0.2	-1.5	-0.2	-0.1	-0.3	-0.2	0.1	0.5	-1.2	-0.1	-1.8	-0.3	-0.3	0.9
Coronary Artery Disease (CAD)	0.4	0.4	1.5	0.3	1.0	0.3	0.8	0.2	-0.1	0.1	-0.7	0.5	-0.2	0.5	1.2	1.0	-0.7
Cardiovascular Disease	0.4	1.2	3.2	1.2	1.2	1.0	1.4	0.6	1.1	1.2	-0.7	1.2	0.7	-0.3	0.8	1.4	1.8
Neuroticism	0.4	1.0	3.7	-1.0	-0.2	-1.6	-1.9	-0.3	-0.9	-1.3	0.1	-0.3	-0.8	0.8	-0.9	-1.1	-0.8
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	2.0	0.3	0.3	0.6	1.0	0.8	0.4	0.3	-0.4	0.5	-0.0	0.0	1.1	1.4	0.0
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	3.5	0.4	-0.7	0.7	-0.1	0.3	0.5	0.6	-0.1	1.0	-0.1	1.9	-0.4	0.4	0.2
Alcohol usually taken with meals	0.4	0.6	2.7	-0.4	-0.2	-0.5	-1.5	-0.5	-0.1	-0.8	-0.1	-0.6	0.6	1.6	-0.8	-0.5	-0.9
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	3.1	-0.6	0.2	-0.8	-0.5	-0.3	-0.2	-1.0	-0.7	-0.3	-0.0	1.8	-0.9	-0.7	-1.2
Hearing difficulty/problems with background noise	0.4	0.6	1.6	0.0	0.9	-1.0	-0.1	0.5	-1.0	-0.3	0.5	-0.6	-1.2	-1.1	0.5	-0.8	-0.9
Noisy workplace	0.4	0.5	1.7	1.0	-1.3	0.2	0.5	0.6	0.8	0.7	-0.5	-0.1	1.1	-0.2	0.5	0.3	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	2.0	-0.1	0.6	-0.1	1.4	-0.7	-0.2	-0.1	-0.7	-1.4	0.6	-1.0	0.4	-0.1	-0.6
Peak expiratory flow (PEF)	0.4	0.9	2.6	0.8	-0.1	1.4	0.0	1.2	1.2	0.8	-1.6	-0.9	0.2	-0.8	0.5	0.3	1.6
Loud music exposure frequency	0.4	0.5	1.5	-0.5	1.2	-0.2	-0.3	-1.0	-0.4	-0.4	0.4	-1.1	-0.3	-1.2	0.2	-0.4	0.0
Glaucoma (self-reported)	0.4	0.4	1.5	0.4	-0.2	0.4	-0.4	-0.4	0.7	0.5	0.0	1.2	0.8	1.1	0.1	0.9	0.6
Health satisfaction	0.4	0.6	1.4	0.1	0.4	0.4	0.9	0.4	1.0	0.5	-0.6	1.2	1.1	1.2	-0.1	0.3	1.0
Emphysema/chronic bronchitis	0.4	0.5	2.7	0.7	0.1	0.4	-0.1	0.3	0.9	0.8	-0.8	0.1	1.7	0.3	0.9	-0.3	-0.1
Average weekly red wine intake	0.4	0.6	4.4	-0.2	2.1	-0.3	0.2	0.2	-0.2	-0.4	-0.9	-1.2	-0.3	-0.7	0.2	-0.8	-0.9
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.4	0.5	1.0	0.3	1.1	1.2	0.4	0.4	-0.3	0.4	0.3	-0.1	0.9	1.1	-0.2
Osteoarthritis (self-reported)	0.4	0.5	1.9	0.5	1.1	0.1	-0.4	0.8	-0.1	0.3	-0.9	-1.4	-0.5	-0.8	0.8	-0.5	-0.9
Risk taking	0.4	0.6	3.4	0.3	1.8	1.0	0.5	-0.0	0.3	0.3	0.5	-0.9	0.7	-1.1	0.9	-0.3	-0.1
Arm predicted mass (left)	0.4	1.9	12.1	1.6	-1.5	1.0	3.5	1.0	1.1	1.1	-0.6	0.7	0.9	-0.0	1.2	1.3	-0.0
Worry (Nagel 2018)	0.3	0.7	3.1	-0.5	1.7	-0.8	-1.3	0.3	0.2	-0.3	-0.4	0.9	-0.2	1.8	-0.2	-0.2	0.3
Alzheimer’s Disease (including proxy)	0.3	0.5	1.8	0.6	1.4	0.0	0.6	-0.4	0.3	0.3	-1.4	0.3	1.0	0.8	0.5	-0.1	-0.3
Reaction Time	0.3	0.5	2.0	-0.5	0.1	-0.6	-1.3	0.1	-0.7	-0.3	0.9	-1.0	-0.5	-0.2	-1.4	-0.9	-0.1
Breast Cancer	0.3	0.7	1.4	-1.2	-1.2	-0.8	-0.3	-0.3	-1.0	-1.1	-0.0	-1.0	-1.2	-0.6	0.0	-0.9	-1.0
Smoking Status	0.3	0.8	8.5	-0.3	-2.9	-0.1	0.8	0.1	-0.3	-0.3	0.5	0.4	-0.4	-1.1	0.5	0.0	0.5
Tanning	0.3	3.5	10.9	2.3	1.7	2.5	0.7	1.9	2.2	2.1	-3.3	-1.1	1.9	-0.9	1.9	0.4	1.1
Pack years adult smoking proportion	0.3	0.4	3.5	-0.7	-1.9	-0.5	0.0	-0.3	-0.4	-0.6	0.2	0.1	-0.0	0.2	-1.0	-0.0	0.2
Current tobacco smoking	0.3	0.5	3.1	-0.3	-1.8	-0.4	1.6	-0.1	-0.4	-0.3	-0.2	0.0	0.1	-0.6	0.3	-0.5	0.1
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.8	0.2	-0.8	-0.5	-0.7	-0.7	-0.6	-0.2	0.7	-0.7	0.0	-0.4	-0.1	-0.5	-0.9
Impedance of leg (left)	0.3	1.7	8.5	0.8	1.0	1.5	-1.0	1.2	1.4	1.1	-1.1	0.3	0.8	-0.8	1.1	1.2	2.9
Trunk fat mass	0.3	1.2	9.5	-0.7	-3.1	-0.5	0.9	-0.8	-0.9	-0.6	0.3	-0.4	-1.3	-1.5	-0.2	-0.2	-0.4
Nervous feelings	0.3	0.5	3.2	-0.5	0.8	-0.9	-0.8	0.0	0.2	-0.3	-0.9	0.4	0.2	1.8	-0.6	-0.7	0.0
Had menopause	0.3	0.4	1.5	-0.4	-1.2	-0.7	-0.5	-0.7	-0.8	-0.6	0.8	0.8	-0.4	0.4	-0.2	-0.0	-0.6
Financial difficulties in last 2 years	0.3	0.4	1.5	0.7	-0.7	-0.0	1.2	0.2	0.7	0.7	-0.5	-0.1	1.2	-0.4	0.7	-0.6	0.3
Hip circumference	0.3	1.5	7.5	-1.0	-2.7	-0.9	1.0	-1.1	-1.2	-0.9	1.1	-0.3	-1.7	-1.4	-0.4	-0.6	-0.7
Worrier / anxious feelings	0.3	0.5	2.4	-0.3	0.4	-0.5	-0.8	-0.7	-0.2	-0.4	-0.4	1.5	0.1	1.4	0.7	0.3	-0.4
Illnesses of mother	0.3	0.4	2.0	-0.3	0.2	-0.4	-0.5	-0.2	-0.3	-0.5	0.2	-0.5	-0.6	1.0	-1.4	-0.9	-0.7
Breastfed as a baby	0.3	0.3	1.1	0.4	1.1	0.7	0.1	0.7	0.4	0.0	-0.4	0.7	0.3	0.9	0.4	0.6	-0.7
High blood pressure (siblings)	0.3	0.4	1.5	-0.8	-0.9	-0.7	-0.9	-1.2	-0.7	-0.7	0.3	-0.1	-0.1	-0.6	-0.2	-0.2	-0.2
Neck or shoulder pain in last month	0.3	0.5	1.4	1.0	0.7	0.5	-0.2	0.4	0.8	0.8	-1.0	-0.2	1.2	0.6	0.3	-0.1	0.4
Alcohol intake frequency.	0.3	0.7	4.1	0.2	-1.0	-0.1	0.9	-0.1	0.2	0.2	-0.4	2.0	0.7	1.2	0.6	0.8	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.4	-0.3	-1.2	-0.3	-0.0	-0.8	-0.1	-0.2	0.3	-0.2	-0.0	-0.3	-0.9	-0.1	1.1
Illnesses of siblings: Diabetes	0.3	0.4	1.1	0.8	-0.4	0.2	0.7	0.4	0.7	0.4	-0.2	1.0	1.0	0.9	-0.1	0.9	0.4
Ever had bowel cancer screening	0.3	0.3	1.7	0.3	0.9	0.3	0.7	0.5	0.2	0.5	0.1	0.1	0.3	-0.7	1.3	0.1	-0.3
Smoking status: Current	0.3	0.5	3.9	-0.2	-2.0	-0.3	1.6	0.0	-0.2	-0.2	-0.4	0.1	0.3	-0.6	0.4	-0.3	0.3
Tinnitus: Yes, now most or all of the time	0.3	0.4	1.3	-0.5	-1.1	-0.4	-0.2	-1.2	-0.8	-0.5	0.6	-0.1	-0.6	-0.5	-0.3	0.2	-0.3
Alcohol drinker status: Never	0.3	0.3	2.2	-0.4	-0.2	-0.5	0.4	-0.5	-0.6	-0.2	1.5	0.5	-0.3	-0.1	-0.1	0.0	-0.8
Arm fat-free mass (left)	0.3	1.8	11.7	1.5	-1.5	0.9	3.4	0.9	1.1	1.0	-0.6	0.6	0.9	0.0	1.2	1.4	-0.1
Heart disease (siblings)	0.3	0.4	1.4	0.2	-0.4	-0.4	-0.5	0.2	0.6	0.2	-1.2	1.0	0.9	0.7	0.6	0.7	0.3
Alcohol drinker status: Previous	0.3	0.4	1.7	-0.4	1.3	-0.6	-0.2	-0.0	-0.4	-0.8	-0.0	-0.8	-0.6	0.0	-0.3	-0.6	-0.8
Pack years of smoking	0.3	0.5	3.2	-0.8	-1.8	-0.7	0.0	-0.4	-0.5	-0.8	0.5	0.0	0.0	-0.0	-1.1	-0.2	0.1
Neuroticism (Nagel 2018)	0.2	0.4	1.3	-0.6	1.0	-1.1	-0.8	0.1	-0.7	-0.7	0.1	-0.1	-0.9	0.3	-0.0	-0.4	-0.8
Hand grip strength (left)	0.2	0.6	2.3	0.5	1.3	0.4	-0.6	0.9	0.3	0.4	-0.5	-1.2	0.1	-1.5	-0.2	-0.6	0.6
Ever had hysterectomy (womb removed)	0.2	0.3	1.4	0.1	-1.2	-0.3	-0.9	-0.4	-0.4	-0.0	0.9	0.3	-0.0	-0.4	0.3	0.3	-0.0
Systolic blood pressure, automated reading	0.2	0.7	3.5	0.3	-0.4	-0.2	1.2	0.4	-0.0	0.5	0.0	1.9	0.0	0.3	1.6	1.1	-0.3
Impedance of leg (right)	0.2	1.2	7.3	0.5	0.7	1.2	-1.5	0.8	1.1	0.7	-0.3	0.3	0.6	-0.8	0.5	1.0	2.7
Relative age voice broke	0.2	0.3	0.7	-0.3	-0.3	-0.7	0.5	-0.8	-0.5	-0.6	0.8	-0.2	0.5	-0.9	-0.5	-0.3	-0.2
Age when periods started (menarche)	0.2	0.6	3.1	0.3	-1.8	-0.0	-1.2	-0.3	0.2	-0.4	0.5	-0.4	1.2	0.7	-0.8	-0.0	-0.4
Waist circumference	0.2	0.6	4.2	-0.0	-2.0	0.1	1.7	-0.3	-0.3	0.0	-0.3	0.2	-0.4	-1.0	0.6	-0.1	-0.2
Hair/balding pattern: Pattern 2	0.2	0.3	1.4	0.2	0.5	0.5	0.0	0.2	0.6	0.1	-0.1	0.5	1.2	1.0	-0.2	0.2	0.2
Pain all over the body in last month	0.2	0.2	0.8	-0.1	-0.9	-0.2	-0.5	0.7	-0.1	-0.2	0.3	-0.0	-0.5	-0.5	0.5	0.1	0.3
Diabetes (self-reported)	0.2	0.4	1.3	0.4	-0.7	0.6	1.0	-0.4	0.2	0.3	-0.2	0.4	0.0	-0.6	1.2	1.0	-0.2
Weight	0.2	1.0	5.8	0.3	-2.4	0.2	2.4	0.1	0.0	0.2	-0.1	0.1	-0.4	-1.1	0.6	0.3	-0.2
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.8	0.6	0.7	-0.0	0.9	0.7	0.0	0.3	-0.7	-0.2	-0.4	-0.8	0.5	0.2	0.2
Mouth/teeth dental problems: Dentures	0.2	0.3	1.1	0.6	-0.9	0.3	0.1	-0.5	0.3	0.7	-0.4	0.6	0.9	-0.4	0.2	-0.4	1.1
Birth weight of first child	0.2	0.3	0.9	-0.2	-1.0	-0.7	0.4	-0.5	-0.2	-0.6	-0.8	-0.6	-0.1	-0.2	0.6	-0.0	-0.9
Number of full brothers	0.2	0.3	0.9	-0.8	0.3	-0.3	-0.4	-0.3	-0.3	-0.5	0.1	-0.8	-1.0	0.0	-0.3	-0.8	-0.2
Medication: Blood pressure	0.2	0.4	1.8	0.2	0.9	0.2	-0.1	0.8	0.1	0.1	0.2	1.3	-0.7	0.6	0.3	1.0	0.0
Heart disease (mother)	0.2	0.2	1.0	0.1	1.0	-0.9	-0.5	-0.1	-0.1	0.3	0.4	-0.6	0.1	-0.8	0.3	0.1	-0.1
Knee pain experienced in last month	0.2	0.4	1.2	0.9	0.1	0.5	0.8	0.8	0.2	1.1	-0.3	-0.3	-0.3	-1.1	0.7	-0.2	0.1
Breast cancer (self-reported)	0.2	0.2	1.1	-0.1	-0.2	-0.2	-0.3	-0.7	-0.4	-0.1	1.0	0.2	-0.4	-1.0	0.1	-0.0	0.3
Medication: Gliclazide	0.2	0.2	1.2	0.3	-0.4	0.5	0.0	0.2	-0.0	0.0	-1.0	0.5	0.1	0.1	1.1	0.5	-0.5
Guilty feelings	0.2	0.2	1.9	0.1	1.4	-0.2	0.7	0.4	-0.1	-0.0	-0.0	-0.5	-0.6	-0.2	-0.1	-0.4	0.2
Medication: Bendroflumethiazide	0.2	0.2	1.3	0.2	0.8	0.2	-0.5	-0.1	0.2	0.2	-1.1	0.2	-0.6	-0.2	0.8	-0.1	0.0
Medication: Atorvastatin	0.2	0.3	1.1	-0.3	0.6	0.3	0.8	-0.9	0.0	-0.2	0.1	-0.3	0.1	-1.0	0.5	0.5	0.4
Ever had prostate specific antigen (PSA) test	0.2	0.3	1.1	0.1	1.1	0.3	-1.1	-0.2	0.1	-0.1	-0.5	-0.7	0.7	0.3	0.2	-0.3	-0.5
Hand grip strength (right)	0.1	0.2	0.8	0.2	-0.8	0.3	-0.1	0.5	-0.0	0.1	0.4	-0.4	-0.2	-0.9	-0.4	-0.4	0.4
Average weekly fortified wine intake	0.1	0.1	0.3	-0.2	0.5	0.0	-0.5	0.4	0.4	0.0	-0.5	0.1	0.2	-0.1	0.0	-0.4	0.3
Number of incorrect matches in round	0.1	0.2	0.9	-0.1	-0.2	-0.3	-0.4	-0.1	-0.5	-0.7	0.9	-0.6	-0.5	-0.2	-0.2	0.3	-0.6
Time employed in main current job	0.1	0.2	0.5	0.5	0.4	-0.2	0.7	0.7	0.1	0.4	-0.2	0.2	-0.4	-0.4	0.3	0.4	0.3
Medication: Lansoprazole	0.1	0.1	0.3	0.2	-0.1	0.4	-0.2	0.2	0.2	0.1	0.1	-0.5	0.2	-0.4	0.6	0.2	-0.2
Loneliness, isolation	0.1	0.2	0.5	0.4	-0.7	-0.1	0.6	0.1	0.0	0.3	0.3	0.5	0.1	-0.6	0.6	0.2	0.4
Number of operations (self-reported)	0.1	0.2	1.4	-0.1	0.2	-0.1	-0.6	-0.2	-0.0	-0.1	-0.6	0.1	-0.1	0.2	1.2	-0.4	-0.7
Pain experienced in last month	0.1	0.2	0.9	-0.3	-0.0	-0.2	-0.3	0.1	0.0	-0.5	0.8	0.9	-0.1	0.7	0.3	0.6	-0.5

Hub : Genes

FADS1

Models

Trait associations