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chr13:49,409,343-52,109,040

Best TWAS P=1.04e-31 · Best GWAS P=6.54e-67 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	DLEU7	0.05	0.00	blup	581	0.02	1.6e-03	1.4	5.9	3.1e-09	-0.46	0.08	0.22	FALSE
2	CommonMind	Brain Pre-frontal Cortex	EBPL	0.34	0.16	bslmm	399	0.33	2.5e-41	1.4	-6.7	2.0e-11	0.04	1.00	0.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	TRIM13	0.15	0.04	lasso	5	0.12	1.1e-14	11.4	-7.7	1.1e-14	0.22	1.00	0.00	FALSE
4	GTEx	Adipose Visceral Omentum	EBPL	0.27	0.03	enet	17	0.20	1.4e-10	8.7	-5.5	3.1e-08	0.09	0.77	0.14	FALSE
5	GTEx	Artery Aorta	EBPL	0.43	0.20	enet	78	0.28	8.1e-16	7.4	-6.5	6.8e-11	0.14	0.99	0.01	FALSE
6	GTEx	Artery Coronary	EBPL	0.48	0.03	enet	99	0.12	9.7e-05	8.7	-6.6	5.4e-11	0.04	0.16	0.44	FALSE
7	GTEx	Artery Tibial	EBPL	0.55	0.32	enet	28	0.46	4.5e-40	1.4	-5.2	2.0e-07	0.05	1.00	0.00	FALSE
8	GTEx	Brain Caudate basal ganglia	EBPL	0.41	0.06	lasso	7	0.12	2.1e-04	7.3	-6.2	5.3e-10	0.02	0.12	0.08	FALSE
9	GTEx	Brain Cerebellar Hemisphere	EBPL	0.54	0.32	enet	17	0.34	1.2e-09	1.4	-6.8	9.9e-12	0.08	0.62	0.07	TRUE
10	GTEx	Brain Cerebellum	EBPL	0.50	0.30	enet	23	0.36	1.8e-11	8.7	-8.4	5.3e-17	0.05	0.86	0.02	FALSE
11	GTEx	Brain Cortex	EBPL	0.36	0.08	enet	24	0.14	1.5e-04	8.7	-8.0	1.8e-15	0.14	0.19	0.10	FALSE
12	GTEx	Brain Frontal Cortex BA9	EBPL	0.50	0.20	enet	18	0.34	7.0e-10	1.4	-5.9	2.9e-09	0.03	0.33	0.31	FALSE
13	GTEx	Brain Nucleus accumbens basal ganglia	EBPL	0.25	0.11	enet	21	0.11	7.9e-04	7.4	-7.3	3.8e-13	0.12	0.11	0.22	FALSE
14	GTEx	Brain Putamen basal ganglia	EBPL	0.31	-0.01	enet	18	0.05	2.9e-02	7.4	-8.2	3.4e-16	0.08	0.04	0.43	FALSE
15	GTEx	Breast Mammary Tissue (Male)	EBPL	0.20	0.05	enet	6	0.03	7.9e-02	1.6	-5.5	3.7e-08	0.11	0.04	0.18	FALSE
16	GTEx	Cells Transformed fibroblasts	EBPL	0.29	0.17	lasso	3	0.22	1.8e-16	-3.5	-6.4	1.6e-10	0.04	1.00	0.00	FALSE
17	GTEx	Colon Transverse	EBPL	0.24	0.19	enet	13	0.11	8.8e-06	-3.5	-5.5	3.3e-08	0.05	0.97	0.01	FALSE
18	GTEx	Esophagus Gastroesophageal Junction	EBPL	0.27	0.24	enet	14	0.26	4.6e-10	7.3	-7.8	5.9e-15	0.02	0.97	0.03	FALSE
19	GTEx	Esophagus Muscularis	EBPL	0.39	0.16	enet	36	0.29	9.2e-18	7.4	-7.3	2.2e-13	0.03	1.00	0.00	FALSE
20	GTEx	Heart Atrial Appendage	EBPL	0.17	0.04	lasso	5	0.05	2.2e-03	8.7	-6.8	1.1e-11	0.07	0.12	0.57	FALSE
21	GTEx	Nerve Tibial	EBPL	0.33	0.09	enet	25	0.27	4.6e-19	7.3	-5.9	3.8e-09	0.05	1.00	0.00	FALSE
22	GTEx	Nerve Tibial	DLEU2	0.11	0.05	lasso	3	0.02	7.8e-03	11.5	11.7	1.0e-31	-0.11	0.51	0.02	TRUE
23	GTEx	Pancreas	EBPL	0.18	0.10	enet	5	0.09	1.6e-04	8.7	-8.1	5.5e-16	0.07	0.36	0.08	FALSE
24	GTEx	Pituitary	EBPL	0.44	0.32	enet	29	0.37	3.1e-10	7.4	-7.3	2.4e-13	-0.02	0.71	0.23	TRUE
25	GTEx	Skin Not Sun Exposed Suprapubic	EBPL	0.34	0.26	enet	12	0.30	4.0e-17	7.4	-6.9	3.8e-12	0.00	1.00	0.00	FALSE
26	GTEx	Skin Sun Exposed Lower leg	EBPL	0.28	0.21	lasso	5	0.20	2.5e-16	7.4	-7.7	9.7e-15	0.02	1.00	0.00	FALSE
27	GTEx	Spleen	RCBTB1	0.37	0.02	lasso	5	0.04	3.5e-02	1.0	-6.5	8.6e-11	0.01	0.04	0.10	FALSE
28	GTEx	Testis	EBPL	0.33	0.17	lasso	6	0.24	8.4e-11	7.3	-8.7	4.2e-18	0.03	0.99	0.01	FALSE
29	GTEx	Thyroid	EBPL	0.36	0.14	enet	33	0.30	5.1e-23	7.3	-8.5	2.0e-17	0.08	1.00	0.00	FALSE
30	METSIM	Adipose	EBPL	0.32	0.12	lasso	7	0.27	1.4e-39	7.3	-6.4	1.6e-10	0.03	1.00	0.00	FALSE
31	NTR	Blood	DLEU7	0.07	0.02	enet	22	0.06	1.3e-19	-6.3	-10.2	1.4e-24	0.61	0.11	0.89	TRUE
32	ROSMAP	Brain Pre-frontal Cortex	EBPL	0.43	0.28	lasso	8	0.43	7.3e-60	7.3	-7.2	4.2e-13	0.03	1.00	0.00	TRUE
33	YFS	Blood	DLEU1	0.13	0.12	lasso	10	0.16	7.4e-49	1.7	-5.4	5.8e-08	-0.06	1.00	0.00	TRUE
34	The Cancer Genome Atlas	Breast Invasive Carcinoma	EBPL	0.07	0.03	enet	11	0.06	2.1e-12	7.4	-6.4	1.2e-10	0.04	0.06	0.94	FALSE
35	The Cancer Genome Atlas	Colon Adenocarcinoma	EBPL	0.20	0.04	blup	59	0.11	6.8e-07	-3.5	-5.6	2.2e-08	0.07	0.60	0.24	FALSE
36	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DLEU2	0.08	0.02	lasso	2	0.01	1.6e-02	-5.6	7.1	1.7e-12	0.02	0.13	0.25	TRUE
37	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EBPL	0.21	0.14	enet	15	0.19	3.6e-21	-3.5	-6.4	1.6e-10	0.08	1.00	0.00	TRUE
38	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	DLEU1	0.13	0.04	lasso	3	0.04	2.6e-03	8.9	-7.9	2.6e-15	0.01	0.23	0.04	TRUE
39	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	EBPL	0.27	0.16	blup	59	0.22	1.0e-12	-3.5	-6.8	1.3e-11	0.06	0.29	0.71	FALSE
40	The Cancer Genome Atlas	Brain Lower Grade Glioma	EBPL	0.22	0.12	enet	7	0.18	2.5e-20	1.4	-6.3	2.5e-10	0.05	0.88	0.12	FALSE
41	The Cancer Genome Atlas	Lung Adenocarcinoma	EBPL	0.07	0.02	blup	59	0.03	8.9e-05	1.4	-5.4	7.0e-08	0.08	0.02	0.81	TRUE
42	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	DLEU2	0.03	0.01	blup	61	0.02	2.4e-03	11.4	10.2	1.5e-24	-0.10	0.01	0.96	FALSE
43	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	EBPL	0.21	0.09	enet	10	0.13	4.9e-06	8.7	-6.3	2.9e-10	0.07	0.00	1.00	FALSE
44	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	EBPL	0.28	0.18	blup	59	0.19	4.3e-08	7.4	-7.0	1.8e-12	0.06	0.01	0.98	FALSE
45	The Cancer Genome Atlas	Prostate Adenocarcinoma	EBPL	0.08	0.01	blup	59	0.04	6.4e-05	7.4	-6.0	2.2e-09	0.04	0.01	0.89	FALSE
46	The Cancer Genome Atlas	Stomach Adenocarcinoma	EBPL	0.10	0.07	enet	7	0.08	2.8e-06	8.7	-7.5	8.5e-14	0.12	0.00	1.00	FALSE
47	The Cancer Genome Atlas	Thyroid Carcinoma	EBPL	0.28	0.10	enet	17	0.26	7.7e-25	-3.5	-5.9	2.7e-09	0.02	0.24	0.76	TRUE
48	The Cancer Genome Atlas	Thyroid Carcinoma	TRIM13	0.04	0.00	blup	26	0.02	8.5e-03	11.6	-10.8	5.8e-27	0.06	0.00	0.46	FALSE