Best TWAS P=1.16e-07 · Best GWAS P=1.63e-08 conditioned to 0.0413
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | PARK7 | 0.02 | 0.01 | lasso | 3 | 0.01 | 1.4e-05 | 5.0 | 5.1 | 3.0e-07 | 0.88 | 0.03 | 0.97 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ERRFI1 | 0.01 | 0.01 | blup | 27 | 0.00 | 4.3e-02 | 5.0 | -5.2 | 2.3e-07 | -0.89 | 0.01 | 0.81 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | PARK7 | 0.03 | 0.03 | enet | 3 | 0.02 | 1.3e-03 | 5.2 | 5.3 | 1.2e-07 | 0.89 | 0.00 | 0.93 | TRUE |