[Hub]/) : Traits : Sitting height : ← →

chr1:9,358,243-12,013,869

Best TWAS P=9.5e-12 · Best GWAS P=3.36e-11 conditioned to 0.495

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	EXOSC10	0.06	0.08	lasso	2	0.07	6.8e-09	6.6	6.6	4.5e-11	0.99	0.01	0.99	FALSE
2	CommonMind	Brain Pre-frontal Cortex	MTOR	0.13	0.15	lasso	4	0.15	5.6e-18	6.2	6.0	1.8e-09	0.88	0.06	0.94	FALSE
3	GTEx	Adipose Subcutaneous	EXOSC10	0.17	0.00	lasso	3	0.00	1.8e-01	6.4	6.2	5.4e-10	0.94	0.02	0.53	FALSE
4	GTEx	Adipose Visceral Omentum	RP4-635E18.7	0.19	0.08	lasso	6	0.05	9.0e-04	6.6	6.2	4.6e-10	0.96	0.02	0.96	FALSE
5	GTEx	Brain Cerebellar Hemisphere	EXOSC10	0.23	0.10	lasso	3	0.12	6.4e-04	5.8	5.7	1.2e-08	0.90	0.05	0.74	FALSE
6	GTEx	Brain Cerebellum	EXOSC10	0.33	0.16	lasso	6	0.18	3.8e-06	6.4	6.4	2.0e-10	0.94	0.03	0.97	FALSE
7	GTEx	Brain Cerebellum	RP4-635E18.7	0.17	0.17	lasso	5	0.09	1.3e-03	6.4	6.1	1.1e-09	0.96	0.03	0.93	FALSE
8	GTEx	Brain Cortex	RP4-635E18.7	0.17	0.05	lasso	4	0.07	6.4e-03	6.2	6.2	7.2e-10	0.91	0.04	0.76	FALSE
9	GTEx	Lung	EXOSC10	0.11	0.07	lasso	4	0.05	1.2e-04	6.4	6.5	1.2e-10	0.97	0.02	0.98	FALSE
10	GTEx	Thyroid	RP4-635E18.7	0.07	0.02	lasso	2	0.01	5.5e-02	6.4	6.3	3.4e-10	0.93	0.02	0.89	FALSE
11	METSIM	Adipose	MTOR	0.04	0.02	bslmm	434	0.02	1.5e-04	6.2	6.3	2.4e-10	0.89	0.03	0.96	FALSE
12	ROSMAP	Brain Pre-frontal Cortex	RBP7	0.08	0.00	bslmm	301	0.01	4.9e-03	2.6	5.6	2.5e-08	0.02	0.04	0.20	TRUE
13	ROSMAP	Brain Pre-frontal Cortex	EXOSC10	0.06	0.06	lasso	2	0.06	4.9e-08	6.6	6.6	4.3e-11	1.00	0.01	0.99	FALSE
14	ROSMAP	Brain Pre-frontal Cortex	MTOR	0.07	0.05	bslmm	423	0.04	2.0e-06	6.2	6.8	9.5e-12	0.87	0.09	0.91	TRUE
15	ROSMAP	Brain Pre-frontal Cortex	RP4-635E18.7	0.23	0.09	enet	24	0.24	3.8e-30	5.6	5.5	3.2e-08	0.71	0.02	0.98	FALSE
16	YFS	Blood	UBE4B	0.03	0.01	bslmm	373	0.02	3.1e-06	3.1	-5.3	1.1e-07	-0.05	0.02	0.98	TRUE
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MTOR	0.02	0.02	blup	54	0.02	5.4e-03	6.2	6.2	6.9e-10	0.91	0.06	0.70	FALSE
18	The Cancer Genome Atlas	Brain Lower Grade Glioma	MTOR	0.03	0.01	blup	54	0.02	5.9e-03	6.2	6.0	1.9e-09	0.88	0.03	0.73	FALSE
19	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	MASP2	0.05	0.03	blup	30	0.04	6.0e-03	1.2	-5.2	2.5e-07	-0.84	0.02	0.57	FALSE