[Hub]/) : Traits : Sitting height :

chr17:45,921,906-47,718,188

Best TWAS P=1.87e-23 · Best GWAS P=2.23e-25 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SNF8 0.08 0.07 lasso 5 0.08 9.3e-10 3.48 -5.3 1.0e-07 -0.61 0.97 0.03 TRUE
2 CommonMind Brain Pre-frontal Cortex TTLL6 0.23 0.12 bslmm 418 0.15 1.7e-17 2.40 -5.5 4.0e-08 -0.20 1.00 0.00 FALSE
3 CommonMind Brain Pre-frontal Cortex UBE2Z 0.05 0.08 lasso 2 0.08 9.8e-10 9.89 -10.0 1.9e-23 -0.92 0.11 0.89 TRUE
4 GTEx Cells EBV-transformed lymphocytes UBE2Z 0.16 0.01 enet 25 0.10 3.5e-04 9.85 5.5 2.9e-08 0.61 0.09 0.70 FALSE
5 GTEx Cells Transformed fibroblasts UBE2Z 0.18 0.00 lasso 5 0.01 3.0e-02 -8.96 8.7 3.3e-18 0.28 0.06 0.20 TRUE
6 GTEx Cells Transformed fibroblasts AC091133.1 0.14 0.07 enet 22 0.09 1.9e-07 4.59 -6.3 3.4e-10 -0.63 0.63 0.35 TRUE
7 GTEx Cells Transformed fibroblasts RP11-463M16.4 0.10 0.00 enet 21 0.01 2.8e-02 4.37 -6.1 1.1e-09 -0.51 0.11 0.62 FALSE
8 GTEx Heart Atrial Appendage ATP5G1 0.22 0.10 enet 6 0.13 1.3e-06 3.58 -5.3 1.1e-07 -0.64 0.93 0.03 FALSE
9 GTEx Heart Left Ventricle ATP5G1 0.24 0.22 lasso 4 0.22 9.3e-12 4.25 -5.3 1.1e-07 -0.64 1.00 0.00 FALSE
10 GTEx Muscle Skeletal ATP5G1 0.13 0.08 enet 18 0.07 5.1e-07 4.55 -6.4 1.9e-10 -0.70 0.98 0.02 TRUE
11 GTEx Muscle Skeletal UBE2Z 0.06 0.02 lasso 8 0.03 9.8e-04 4.25 -8.2 2.6e-16 -0.81 0.12 0.84 FALSE
12 GTEx Testis HOXB3 0.19 0.00 lasso 6 0.03 2.1e-02 -0.23 -5.9 3.2e-09 -0.32 0.11 0.14 FALSE
13 GTEx Testis CALCOCO2 0.26 0.24 lasso 2 0.24 8.2e-11 6.10 5.9 2.8e-09 0.25 0.99 0.00 FALSE
14 GTEx Testis SNF8 0.23 0.11 lasso 5 0.08 1.6e-04 3.53 -5.4 6.0e-08 -0.64 0.47 0.37 FALSE
15 GTEx Testis HOXB2 0.21 0.00 enet 22 0.07 5.9e-04 2.22 -5.8 8.9e-09 -0.23 0.19 0.08 FALSE
16 GTEx Testis HOXB-AS1 0.18 -0.01 enet 35 0.04 5.3e-03 -1.51 -8.8 1.0e-18 -0.45 0.12 0.15 TRUE
17 GTEx Whole Blood UBE2Z 0.08 0.01 lasso 6 0.02 4.9e-03 9.87 9.5 1.9e-21 0.88 0.05 0.95 FALSE
18 METSIM Adipose HOXB9 0.06 0.03 enet 17 0.05 9.9e-08 4.74 -5.8 7.4e-09 -0.11 1.00 0.00 TRUE
19 METSIM Adipose UBE2Z 0.06 0.06 enet 16 0.04 3.2e-06 9.89 9.9 3.6e-23 0.93 0.23 0.77 FALSE
20 YFS Blood UBE2Z 0.06 0.03 enet 19 0.06 1.5e-18 5.47 5.3 1.2e-07 0.24 1.00 0.00 FALSE
21 The Cancer Genome Atlas Breast Invasive Carcinoma SNF8 0.01 0.01 blup 47 0.01 9.1e-03 9.84 -8.2 1.9e-16 -0.87 0.05 0.30 FALSE
22 The Cancer Genome Atlas Glioblastoma Multiforme SNF8 0.09 0.06 blup 47 0.07 4.3e-03 7.71 -8.2 2.1e-16 -0.87 0.06 0.44 FALSE
23 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma HOXB7 0.03 0.03 enet 4 0.03 6.0e-04 6.14 -5.9 3.9e-09 0.11 0.06 0.75 FALSE
24 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SNF8 0.05 0.01 blup 47 0.03 2.1e-04 3.48 -6.6 3.6e-11 -0.78 0.07 0.56 FALSE
25 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ZNF652 0.03 0.03 enet 5 0.03 2.6e-04 -5.69 6.1 9.2e-10 -0.08 0.01 0.98 FALSE
26 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SNF8 0.03 0.01 blup 47 0.03 1.0e-02 10.18 -8.5 1.6e-17 -0.91 0.02 0.64 FALSE
27 The Cancer Genome Atlas Brain Lower Grade Glioma CALCOCO2 0.03 0.00 blup 50 0.01 1.9e-02 -6.21 -6.6 3.1e-11 -0.62 0.06 0.47 FALSE
28 The Cancer Genome Atlas Brain Lower Grade Glioma TTLL6 0.03 0.00 blup 59 0.02 2.7e-03 7.33 5.6 2.3e-08 0.56 0.02 0.82 FALSE
29 The Cancer Genome Atlas Brain Lower Grade Glioma ZNF652 0.06 0.03 lasso 4 0.02 1.6e-03 -5.59 5.3 1.4e-07 -0.04 0.11 0.76 FALSE
30 The Cancer Genome Atlas Lung Adenocarcinoma ATP5G1 0.04 0.01 enet 6 0.03 5.4e-05 9.84 8.2 2.9e-16 0.81 0.01 0.94 FALSE
31 The Cancer Genome Atlas Lung Adenocarcinoma CALCOCO2 0.04 0.03 blup 50 0.02 1.6e-03 3.15 5.2 2.2e-07 0.26 0.03 0.06 FALSE
32 The Cancer Genome Atlas Lung Adenocarcinoma ZNF652 0.05 0.02 blup 55 0.02 2.5e-03 -6.59 5.5 4.5e-08 -0.09 0.01 0.98 FALSE
33 The Cancer Genome Atlas Prostate Adenocarcinoma SNF8 0.05 0.06 blup 47 0.06 1.0e-06 3.88 -6.6 4.7e-11 -0.79 0.52 0.47 FALSE
34 The Cancer Genome Atlas Prostate Adenocarcinoma TTLL6 0.03 0.04 lasso 2 0.03 3.4e-04 -8.08 8.1 6.3e-16 0.52 0.05 0.83 FALSE
35 The Cancer Genome Atlas Thyroid Carcinoma HOXB6 0.04 0.00 blup 51 0.01 3.3e-02 5.96 -6.6 5.5e-11 0.03 0.01 0.82 TRUE