Best TWAS P=6.57e-08 · Best GWAS P=4.35e-07 conditioned to 0.872
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | CCNE1 | 0.27 | 0.22 | lasso | 8 | 0.24 | 2.5e-19 | 5.1 | 5.2 | 1.9e-07 | 0.96 | 0.01 | 0.99 | FALSE |
| 2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | CCNE1 | 0.03 | 0.02 | blup | 39 | 0.02 | 4.5e-03 | 5.1 | 5.3 | 9.1e-08 | 0.90 | 0.01 | 0.94 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CCNE1 | 0.03 | 0.03 | enet | 5 | 0.03 | 3.2e-04 | 5.1 | -5.4 | 6.6e-08 | -0.92 | 0.01 | 0.98 | TRUE |