[Hub]/) : Traits : Sitting height : ← →

chr20:19,649,716-21,919,054

Best TWAS P=2.84e-12 · Best GWAS P=1.68e-13 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex INSM1 0.07 0.00 bslmm 522 0.02 2.2e-03 5.4 6.3 3.4e-10 -0.01 0.06 0.32 TRUE
2 GTEx Artery Tibial PLK1S1 0.07 0.08 enet 10 0.08 4.0e-07 7.3 7.0 2.8e-12 0.97 0.02 0.98 TRUE
3 GTEx Esophagus Mucosa PLK1S1 0.11 0.11 lasso 5 0.09 7.8e-07 5.9 5.9 3.9e-09 0.83 0.16 0.84 FALSE
4 GTEx Skin Not Sun Exposed Suprapubic PLK1S1 0.21 0.09 lasso 6 0.12 5.3e-07 7.0 6.1 8.5e-10 0.93 0.06 0.94 FALSE
5 GTEx Skin Sun Exposed Lower leg PLK1S1 0.15 0.13 enet 10 0.15 3.9e-12 6.0 5.8 6.5e-09 0.83 0.96 0.04 FALSE
6 GTEx Testis PLK1S1 0.64 0.34 enet 33 0.39 1.0e-18 6.0 6.5 7.0e-11 0.79 0.56 0.44 FALSE
7 GTEx Whole Blood PLK1S1 0.08 0.04 enet 9 0.02 4.0e-03 6.0 5.8 8.6e-09 0.89 0.06 0.94 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma PLK1S1 0.05 0.07 enet 9 0.07 5.5e-15 5.7 6.2 7.0e-10 0.88 0.17 0.83 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma PLK1S1 0.04 0.03 blup 64 0.04 4.0e-05 6.0 6.4 1.5e-10 0.88 0.15 0.84 FALSE
10 The Cancer Genome Atlas Pancreatic Adenocarcinoma PLK1S1 0.09 0.02 blup 64 0.05 3.1e-03 4.9 6.2 5.3e-10 0.78 0.03 0.51 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma PLK1S1 0.19 0.12 enet 14 0.13 4.3e-13 5.8 6.6 3.8e-11 0.80 0.97 0.03 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma PLK1S1 0.06 0.04 lasso 3 0.04 1.5e-04 5.8 5.8 5.1e-09 0.85 0.18 0.53 FALSE