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chr20:24,247,240-26,253,682

Best TWAS P=4.39e-09 · Best GWAS P=2.96e-09 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ABHD12	0.10	0.17	blup	405	0.17	1.7e-20	5.2	5.4	8.2e-08	0.86	0.17	0.83	FALSE
2	GTEx	Artery Aorta	NINL	0.17	0.18	lasso	6	0.19	1.5e-10	5.3	5.5	3.2e-08	0.89	0.10	0.90	FALSE
3	GTEx	Artery Tibial	ABHD12	0.12	0.12	enet	25	0.15	7.1e-12	4.1	5.2	2.4e-07	0.88	0.20	0.80	FALSE
4	GTEx	Brain Cerebellar Hemisphere	PYGB	0.20	0.16	lasso	5	0.12	5.8e-04	5.6	-5.4	6.2e-08	-0.89	0.07	0.80	FALSE
5	GTEx	Brain Cerebellar Hemisphere	ENTPD6	0.22	0.26	lasso	3	0.17	3.8e-05	5.6	-5.6	2.6e-08	-0.97	0.03	0.97	FALSE
6	GTEx	Brain Cerebellum	ENTPD6	0.15	0.23	enet	8	0.14	4.6e-05	5.7	-5.9	4.4e-09	-0.97	0.02	0.98	TRUE
7	GTEx	Breast Mammary Tissue	ABHD12	0.08	0.09	lasso	5	0.09	3.3e-05	5.3	5.2	2.0e-07	0.85	0.14	0.81	FALSE
8	GTEx	Cells Transformed fibroblasts	ABHD12	0.24	0.33	lasso	4	0.35	6.3e-27	5.3	5.2	2.4e-07	0.90	0.13	0.87	FALSE
9	GTEx	Esophagus Gastroesophageal Junction	PYGB	0.11	0.04	enet	28	0.13	2.2e-05	5.9	5.4	5.3e-08	0.80	0.04	0.90	FALSE
10	GTEx	Esophagus Gastroesophageal Junction	ABHD12	0.15	0.14	lasso	13	0.14	7.0e-06	5.6	5.6	2.5e-08	0.97	0.05	0.95	FALSE
11	GTEx	Esophagus Mucosa	NANP	0.07	0.00	lasso	7	0.01	5.1e-02	5.9	-5.7	1.3e-08	-0.78	0.04	0.75	FALSE
12	GTEx	Heart Atrial Appendage	ABHD12	0.07	0.06	enet	16	0.06	1.0e-03	5.2	5.3	1.1e-07	0.91	0.13	0.84	FALSE
13	GTEx	Heart Left Ventricle	ABHD12	0.15	0.14	lasso	10	0.12	4.0e-07	5.1	5.5	3.5e-08	0.91	0.14	0.86	FALSE
14	GTEx	Liver	ABHD12	0.20	0.20	lasso	19	0.15	7.3e-05	5.3	5.3	1.2e-07	0.91	0.14	0.86	FALSE
15	GTEx	Liver	APMAP	0.20	-0.01	lasso	9	0.00	3.8e-01	5.2	5.2	1.9e-07	0.63	0.10	0.49	FALSE
16	GTEx	Pituitary	ABHD12	0.27	0.31	enet	25	0.31	1.8e-08	5.3	5.5	3.7e-08	0.86	0.11	0.89	FALSE
17	GTEx	Skin Sun Exposed Lower leg	ABHD12	0.07	0.03	lasso	10	0.05	7.3e-05	5.7	5.5	3.5e-08	0.93	0.06	0.93	FALSE
18	GTEx	Thyroid	ABHD12	0.05	0.04	lasso	5	0.03	3.9e-03	5.2	-5.3	1.0e-07	-0.92	0.12	0.84	FALSE
19	GTEx	Whole Blood	PYGB	0.17	0.14	enet	22	0.18	2.7e-16	5.3	5.1	2.7e-07	0.91	0.04	0.96	FALSE
20	NTR	Blood	PYGB	0.07	0.10	enet	22	0.12	3.6e-36	5.2	5.3	1.2e-07	0.90	0.18	0.82	FALSE
21	ROSMAP	Brain Pre-frontal Cortex	ABHD12	0.26	0.35	enet	35	0.42	7.9e-58	4.2	5.4	6.3e-08	0.82	0.20	0.80	FALSE
22	YFS	Blood	ACSS1	0.09	0.01	enet	18	0.03	7.2e-10	-3.3	5.6	2.4e-08	0.41	0.95	0.04	FALSE
23	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	PYGB	0.08	0.04	blup	74	0.06	1.0e-03	5.2	-5.3	1.1e-07	-0.90	0.03	0.88	FALSE
24	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ABHD12	0.04	0.03	blup	77	0.04	4.0e-05	5.2	5.2	2.5e-07	0.90	0.08	0.92	FALSE
25	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ENTPD6	0.29	0.17	lasso	4	0.18	1.0e-10	4.3	-5.3	1.3e-07	-0.84	0.03	0.97	FALSE
26	The Cancer Genome Atlas	Brain Lower Grade Glioma	ABHD12	0.04	0.06	blup	77	0.06	2.2e-07	5.2	5.3	1.3e-07	0.91	0.07	0.93	FALSE
27	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ABHD12	0.07	0.05	blup	77	0.05	2.4e-03	5.2	5.2	1.6e-07	0.90	0.07	0.77	FALSE
28	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	ABHD12	0.08	0.09	blup	80	0.09	1.7e-06	5.2	5.2	2.2e-07	0.90	0.08	0.92	FALSE
29	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ENTPD6	0.07	0.07	lasso	1	0.04	9.2e-03	5.6	-5.6	2.8e-08	-0.94	0.01	0.89	FALSE
30	The Cancer Genome Atlas	Thyroid Carcinoma	ENTPD6	0.16	0.14	lasso	4	0.13	1.2e-12	5.6	-5.7	1.6e-08	-0.96	0.01	0.99	FALSE
31	The Cancer Genome Atlas	Thyroid Carcinoma	NINL	0.08	0.14	lasso	11	0.13	2.9e-12	5.2	-5.4	6.7e-08	-0.91	0.03	0.97	FALSE