Best TWAS P=5.99e-11 · Best GWAS P=7.18e-18 conditioned to 2.07e-09
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | EYA2 | 0.42 | 0.32 | lasso | 6 | 0.34 | 1.6e-19 | 5.5 | -5.6 | 2e-08 | -0.67 | 1.00 | 0.00 | FALSE |
2 | METSIM | Adipose | EYA2 | 0.05 | 0.01 | enet | 21 | 0.03 | 6.6e-05 | 7.8 | -6.5 | 6e-11 | -0.55 | 0.08 | 0.85 | TRUE |