Best TWAS P=6.75e-09 · Best GWAS P=2.41e-08 conditioned to 0.339
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | SPRTN | 0.05 | 0.02 | enet | 8 | 0.01 | 0.03180 | 5.6 | 5.8 | 6.8e-09 | 0.89 | 0.01 | 0.96 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | EGLN1 | 0.07 | 0.02 | blup | 64 | 0.04 | 0.00352 | 4.9 | 5.2 | 2.2e-07 | 0.85 | 0.02 | 0.81 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | C1orf124 | 0.05 | 0.01 | blup | 44 | 0.03 | 0.00053 | 4.9 | 5.4 | 8.4e-08 | 0.80 | 0.02 | 0.94 | FALSE |