Best TWAS P=1.42e-07 · Best GWAS P=1.94e-09 conditioned to 7.3e-06
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Mucosa | COX7A2L | 0.30 | 0.36 | enet | 31 | 0.38 | 2.2e-26 | 4.9 | 5.2 | 2.0e-07 | -0.31 | 0.71 | 0.29 | FALSE |
2 | GTEx | Liver | COX7A2L | 0.45 | 0.44 | lasso | 6 | 0.44 | 1.7e-13 | 4.9 | 5.1 | 2.9e-07 | -0.41 | 0.48 | 0.52 | FALSE |
3 | GTEx | Lung | COX7A2L | 0.26 | 0.30 | lasso | 5 | 0.28 | 5.8e-22 | 4.9 | 5.3 | 1.4e-07 | -0.34 | 0.74 | 0.26 | TRUE |
4 | GTEx | Pancreas | COX7A2L | 0.36 | 0.37 | lasso | 4 | 0.35 | 2.1e-15 | 4.9 | 5.1 | 2.8e-07 | -0.35 | 0.42 | 0.58 | FALSE |
5 | GTEx | Spleen | COX7A2L | 0.30 | 0.22 | enet | 10 | 0.25 | 4.7e-07 | 4.9 | 5.2 | 1.9e-07 | -0.34 | 0.23 | 0.72 | FALSE |