Best TWAS P=1.49e-07 · Best GWAS P=8.53e-11 conditioned to 1.59e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | CAMKMT | 0.06 | 0.06 | lasso | 4 | 0.05 | 1.6e-06 | 5.2 | -5.2 | 1.5e-07 | 0.09 | 0.83 | 0.17 | TRUE |
| 2 | The Cancer Genome Atlas | Glioblastoma Multiforme | PPM1B | 0.14 | 0.04 | blup | 65 | 0.04 | 2.4e-02 | 1.0 | 5.1 | 3.0e-07 | 0.65 | 0.02 | 0.36 | TRUE |