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chr2:35,884,899-37,567,226

Best TWAS P=1.74e-13 · Best GWAS P=8.61e-12 conditioned to 0.966

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	FEZ2	0.16	0.24	lasso	2	0.22	1.3e-26	6.1	-6.2	6.8e-10	0.48	0.20	0.80	FALSE
2	GTEx	Adipose Subcutaneous	AC007401.1	0.10	0.02	lasso	4	0.02	5.4e-03	5.5	6.2	5.9e-10	-0.41	0.37	0.25	FALSE
3	GTEx	Artery Tibial	CRIM1	0.10	0.04	lasso	4	0.05	1.4e-04	5.5	-6.8	1.4e-11	0.54	0.15	0.79	FALSE
4	GTEx	Artery Tibial	RP11-78I14.1	0.10	0.08	enet	16	0.07	4.2e-06	5.5	-6.8	1.0e-11	0.58	0.22	0.67	FALSE
5	GTEx	Brain Cerebellar Hemisphere	CRIM1	0.36	0.21	lasso	5	0.16	5.4e-05	4.9	5.3	1.0e-07	-0.45	0.31	0.15	FALSE
6	GTEx	Skin Sun Exposed Lower leg	RP11-78I14.1	0.14	0.06	enet	8	0.04	6.0e-04	-6.5	-5.2	2.2e-07	0.76	0.02	0.95	FALSE
7	GTEx	Spleen	FEZ2	0.42	0.16	enet	25	0.17	3.9e-05	5.1	6.4	1.3e-10	-0.46	0.27	0.25	FALSE
8	GTEx	Whole Blood	AC007401.1	0.06	0.06	lasso	5	0.05	4.6e-05	4.9	5.2	2.6e-07	-0.48	0.74	0.06	FALSE
9	NTR	Blood	CRIM1	0.09	0.10	lasso	6	0.11	3.1e-32	5.6	-5.5	5.1e-08	0.53	0.75	0.25	FALSE
10	ROSMAP	Brain Pre-frontal Cortex	FEZ2	0.41	0.55	lasso	5	0.58	3.1e-93	4.7	-5.5	4.3e-08	0.50	0.81	0.19	FALSE
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	FEZ2	0.01	0.01	blup	85	0.01	1.0e-03	4.8	-7.1	1.5e-12	0.63	0.20	0.40	FALSE
12	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	FEZ2	0.06	0.05	lasso	4	0.04	3.3e-03	5.9	-5.5	4.3e-08	0.47	0.18	0.13	FALSE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	CRIM1	0.05	0.04	lasso	2	0.03	3.2e-04	-5.6	-5.6	1.9e-08	0.46	0.22	0.23	FALSE
14	The Cancer Genome Atlas	Prostate Adenocarcinoma	FEZ2	0.06	0.05	blup	87	0.08	1.4e-08	4.7	-5.4	8.3e-08	0.45	0.77	0.22	FALSE
15	The Cancer Genome Atlas	Testicular Germ Cell Tumors	FEZ2	0.18	0.21	lasso	6	0.21	5.3e-08	-6.6	-7.4	1.7e-13	0.92	0.00	1.00	TRUE