Best TWAS P=1.26e-11 · Best GWAS P=4.38e-10 conditioned to 1.82e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | C2orf40 | 0.20 | 0.11 | bslmm | 483 | 0.13 | 7.8e-16 | 2.5 | -6.8 | 1.5e-11 | 0.04 | 0.92 | 0.00 | FALSE |
| 2 | GTEx | Nerve Tibial | C2orf40 | 0.34 | 0.01 | enet | 27 | 0.11 | 1.9e-08 | 2.5 | -5.2 | 1.8e-07 | 0.05 | 0.50 | 0.13 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | UXS1 | 0.06 | 0.01 | lasso | 3 | 0.01 | 7.3e-03 | -4.7 | -5.8 | 9.0e-09 | -0.04 | 0.02 | 0.17 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | UXS1 | 0.04 | 0.03 | enet | 4 | 0.02 | 1.1e-03 | -5.2 | -6.8 | 1.3e-11 | 0.02 | 0.01 | 0.68 | TRUE |