Best TWAS P=4.12e-09 · Best GWAS P=6.03e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | BCL2L11 | 0.04 | 0.04 | lasso | 2 | 0.03 | 0.0002 | 5.8 | -5.9 | 4.1e-09 | -1.00 | 0.01 | 0.98 | TRUE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | BCL2L11 | 0.07 | 0.01 | blup | 71 | 0.06 | 0.0002 | -5.0 | -5.5 | 4.9e-08 | -0.85 | 0.02 | 0.94 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | BCL2L11 | 0.04 | 0.02 | lasso | 3 | 0.02 | 0.0057 | 4.2 | -5.2 | 2.5e-07 | -0.61 | 0.05 | 0.25 | FALSE |