Best TWAS P=5.95e-15 · Best GWAS P=1.39e-15 conditioned to 0.0112
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | CTNNB1 | 0.30 | 0.00 | lasso | 4 | 0.01 | 1.0e-01 | 7.7 | -7.6 | 2.3e-14 | -0.88 | 0.03 | 0.54 | FALSE |
| 2 | GTEx | Nerve Tibial | CTNNB1 | 0.05 | 0.00 | enet | 4 | 0.00 | 2.0e-01 | 5.4 | 5.7 | 1.3e-08 | 0.65 | 0.09 | 0.41 | FALSE |
| 3 | NTR | Blood | CTNNB1 | 0.04 | 0.04 | lasso | 6 | 0.04 | 4.6e-13 | 7.6 | -7.8 | 6.0e-15 | -0.85 | 0.04 | 0.96 | TRUE |