[Hub]/) : Traits : Sitting height : ← →

chr3:37,332,662-38,766,338

Best TWAS P=4.09e-25 · Best GWAS P=1.5e-21 conditioned to 0.4

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PLCD1 0.07 0.02 lasso 4 0.03 4.2e-04 4.7 8.3 1.5e-16 0.70 0.04 0.90 FALSE
2 CommonMind Brain Pre-frontal Cortex VILL 0.26 0.38 lasso 3 0.38 1.9e-49 8.6 -8.9 5.3e-19 -0.79 0.84 0.16 FALSE
3 GTEx Brain Caudate basal ganglia VILL 0.35 0.38 lasso 8 0.33 3.9e-10 8.8 -9.3 1.6e-20 -0.84 0.05 0.95 FALSE
4 GTEx Brain Cortex VILL 0.33 0.29 lasso 2 0.25 1.8e-07 9.4 -9.5 1.5e-21 -0.91 0.02 0.98 FALSE
5 GTEx Brain Frontal Cortex BA9 VILL 0.31 0.30 enet 11 0.34 7.9e-10 9.4 -9.8 1.7e-22 -0.95 0.02 0.98 FALSE
6 GTEx Brain Nucleus accumbens basal ganglia VILL 0.31 0.13 lasso 6 0.12 5.2e-04 8.8 -8.9 3.6e-19 -0.80 0.02 0.92 FALSE
7 GTEx Brain Putamen basal ganglia VILL 0.38 0.31 lasso 7 0.26 7.9e-07 8.8 -8.0 1.0e-15 -0.71 0.07 0.86 FALSE
8 ROSMAP Brain Pre-frontal Cortex VILL 0.34 0.46 lasso 3 0.46 3.1e-65 8.6 -8.8 1.0e-18 -0.82 0.91 0.09 FALSE
9 ROSMAP Brain Pre-frontal Cortex PLCD1 0.13 0.12 bslmm 421 0.12 6.6e-15 9.4 -8.7 3.3e-18 -0.91 0.01 0.99 FALSE
10 YFS Blood PLCD1 0.07 0.08 enet 15 0.08 8.0e-25 9.4 10.4 4.1e-25 0.95 0.01 0.99 TRUE
11 The Cancer Genome Atlas Breast Invasive Carcinoma PLCD1 0.01 0.02 blup 55 0.01 7.3e-03 9.5 9.1 5.7e-20 0.90 0.01 0.94 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma VILL 0.03 0.01 blup 52 0.01 1.5e-02 9.4 -9.1 6.9e-20 -0.87 0.01 0.69 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma CTDSPL 0.04 0.01 blup 78 0.02 1.0e-03 9.4 -7.5 6.0e-14 -0.67 0.02 0.90 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma PLCD1 0.05 0.04 enet 8 0.04 6.3e-05 9.5 9.7 1.9e-22 0.97 0.01 0.99 FALSE