[Hub]/) : Traits : Sitting height :

chr4:16,922,182-18,507,692

Best TWAS P=4.14e-89 · Best GWAS P=1.95e-80 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MED28 0.07 0.09 enet 9 0.11 7.1e-13 -4.63 5.1 2.9e-07 -0.18 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous DCAF16 0.21 0.15 lasso 3 0.17 5.1e-14 12.31 12.3 8.1e-35 -0.24 1.00 0.00 FALSE
3 GTEx Adipose Visceral Omentum DCAF16 0.19 0.06 enet 10 0.11 3.9e-06 12.31 13.8 3.2e-43 -0.35 0.35 0.35 TRUE
4 GTEx Artery Aorta DCAF16 0.10 0.01 enet 6 0.02 4.7e-02 -17.58 20.0 4.1e-89 -0.81 0.08 0.66 TRUE
5 GTEx Artery Tibial DCAF16 0.16 0.16 lasso 5 0.13 1.5e-10 13.86 15.3 4.3e-53 -0.36 1.00 0.00 FALSE
6 GTEx Breast Mammary Tissue DCAF16 0.12 0.08 lasso 4 0.10 6.4e-06 12.37 15.9 3.4e-57 -0.52 0.10 0.74 TRUE
7 GTEx Breast Mammary Tissue (Male) DCAF16 0.24 0.03 enet 18 -0.01 4.4e-01 -17.71 18.5 9.6e-77 -0.76 0.04 0.66 FALSE
8 GTEx Breast Mammary Tissue (Female) DCAF16 0.16 0.13 lasso 2 0.06 7.8e-03 12.31 12.1 7.3e-34 -0.27 0.06 0.10 FALSE
9 GTEx Esophagus Mucosa DCAF16 0.10 0.02 lasso 4 0.02 8.3e-03 12.37 13.6 3.7e-42 -0.37 0.14 0.36 FALSE
10 GTEx Esophagus Muscularis DCAF16 0.16 0.14 lasso 3 0.14 9.3e-09 12.31 12.2 2.9e-34 -0.27 0.99 0.00 FALSE
11 GTEx Nerve Tibial DCAF16 0.16 0.14 lasso 3 0.14 2.8e-10 12.31 14.0 2.6e-44 -0.37 0.99 0.00 FALSE
12 GTEx Pituitary DCAF16 0.27 0.20 enet 15 0.19 1.3e-05 12.31 11.8 3.3e-32 -0.38 0.08 0.25 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic DCAF16 0.16 0.08 lasso 5 0.12 4.4e-07 12.43 13.9 3.5e-44 -0.35 0.64 0.05 TRUE
14 GTEx Skin Sun Exposed Lower leg DCAF16 0.14 0.12 enet 14 0.12 5.4e-10 12.37 13.8 3.0e-43 -0.28 1.00 0.00 FALSE
15 GTEx Spleen DCAF16 0.35 0.02 lasso 5 0.11 8.5e-04 12.31 18.7 5.2e-78 -0.66 0.04 0.66 FALSE
16 GTEx Stomach DCAF16 0.21 0.04 lasso 6 0.02 5.6e-02 13.68 15.0 1.4e-50 -0.26 0.19 0.05 TRUE
17 GTEx Thyroid DCAF16 0.11 0.02 lasso 5 0.03 2.3e-03 12.31 17.8 1.7e-70 -0.54 0.18 0.69 FALSE
18 ROSMAP Brain Pre-frontal Cortex FAM184B 0.17 0.14 enet 31 0.18 5.1e-23 -4.63 -7.2 4.5e-13 0.26 1.00 0.00 TRUE
19 ROSMAP Brain Pre-frontal Cortex MED28 0.02 0.01 bslmm 411 0.00 1.9e-01 -4.89 7.7 1.3e-14 -0.30 0.22 0.03 FALSE
20 ROSMAP Brain Pre-frontal Cortex DCAF16 0.04 0.02 bslmm 379 0.01 3.9e-02 -17.72 17.7 5.2e-70 -0.83 0.03 0.88 FALSE
21 YFS Blood DCAF16 0.02 0.02 lasso 1 0.01 1.1e-04 13.86 13.9 1.1e-43 -0.25 0.84 0.03 FALSE
22 The Cancer Genome Atlas Breast Invasive Carcinoma NCAPG 0.03 0.04 enet 5 0.04 8.1e-09 -0.77 -7.1 1.5e-12 0.55 0.95 0.04 TRUE
23 The Cancer Genome Atlas Colon Adenocarcinoma NCAPG 0.08 0.04 blup 34 0.09 1.1e-05 -17.50 -15.3 7.0e-53 0.84 0.06 0.91 FALSE
24 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma NCAPG 0.14 0.07 lasso 3 0.07 5.2e-08 -17.72 -17.3 7.8e-67 0.84 0.77 0.23 FALSE
25 The Cancer Genome Atlas Brain Lower Grade Glioma DCAF16 0.09 0.02 lasso 3 0.04 5.2e-05 13.86 19.5 5.7e-85 -0.64 0.02 0.96 FALSE
26 The Cancer Genome Atlas Brain Lower Grade Glioma NCAPG 0.02 0.03 lasso 1 0.02 9.0e-04 -17.50 -17.5 1.3e-68 0.88 0.03 0.54 FALSE
27 The Cancer Genome Atlas Lung Adenocarcinoma NCAPG 0.06 0.02 blup 34 0.04 1.0e-05 -17.50 -10.8 2.3e-27 0.68 0.13 0.06 FALSE
28 The Cancer Genome Atlas Prostate Adenocarcinoma DCAF16 0.04 0.04 blup 31 0.04 2.2e-05 12.31 17.5 1.3e-68 -0.58 0.23 0.35 FALSE
29 The Cancer Genome Atlas Prostate Adenocarcinoma NCAPG 0.02 0.02 blup 34 0.02 3.4e-03 -16.24 -14.9 3.4e-50 0.76 0.01 0.88 FALSE
30 The Cancer Genome Atlas Thyroid Carcinoma DCAF16 0.07 0.04 blup 31 0.07 4.9e-07 13.68 18.6 1.3e-77 -0.65 0.16 0.76 FALSE