[Hub]/) : Traits : Sitting height :

chr4:7,060,959-8,731,330

Best TWAS P=1.36e-09 · Best GWAS P=5.35e-14 conditioned to 2.32e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellar Hemisphere AFAP1-AS1 0.33 0.16 lasso 7 0.16 5.9e-05 5.97 5.7 1.4e-08 0.00 0.08 0.74 FALSE
2 GTEx Brain Cerebellum AFAP1 0.47 0.19 lasso 4 0.19 2.8e-06 -3.01 5.2 2.4e-07 0.00 0.10 0.82 FALSE
3 GTEx Cells Transformed fibroblasts AFAP1 0.26 0.10 enet 39 0.13 3.6e-10 -5.04 -6.0 2.3e-09 -0.02 0.01 0.99 TRUE
4 GTEx Cells Transformed fibroblasts AFAP1-AS1 0.20 0.09 enet 31 0.07 4.7e-06 -7.01 -5.5 3.1e-08 -0.05 0.00 1.00 FALSE
5 GTEx Esophagus Mucosa AFAP1 0.48 0.40 enet 29 0.43 3.9e-31 4.94 5.4 6.1e-08 -0.02 0.98 0.02 FALSE
6 GTEx Skin Sun Exposed Lower leg AFAP1-AS1 0.34 0.26 lasso 5 0.24 8.3e-20 4.94 5.1 2.8e-07 -0.01 0.99 0.01 FALSE
7 GTEx Whole Blood AFAP1-AS1 0.36 0.33 lasso 8 0.33 2.6e-31 4.94 5.2 2.5e-07 -0.01 0.97 0.03 FALSE
8 METSIM Adipose AFAP1 0.05 0.03 enet 13 0.03 1.3e-05 4.94 5.3 1.2e-07 -0.01 0.35 0.62 FALSE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CPZ 0.03 0.00 blup 80 0.01 1.9e-02 -3.68 6.1 1.4e-09 -0.55 0.03 0.23 TRUE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CPZ 0.09 0.01 blup 80 0.03 4.4e-04 -0.28 5.3 9.7e-08 -0.54 0.02 0.52 FALSE