Best TWAS P=8.66e-08 · Best GWAS P=1.23e-08 conditioned to 6.62e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | SLC6A7 | 0.09 | 0.06 | lasso | 1 | 0.04 | 1.1e-05 | 5.3 | 5.3 | 1.1e-07 | 0.36 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Brain Hypothalamus | ZNF300P1 | 0.68 | 0.24 | lasso | 16 | 0.35 | 4.1e-09 | -3.6 | -5.2 | 2.4e-07 | 0.05 | 0.02 | 0.72 | FALSE |
| 3 | GTEx | Nerve Tibial | ZNF300 | 0.13 | 0.05 | lasso | 4 | 0.09 | 7.0e-07 | 4.5 | -5.2 | 2.4e-07 | 0.05 | 0.01 | 0.88 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | LOC134466 | 0.09 | 0.06 | lasso | 4 | 0.07 | 1.7e-08 | 4.6 | -5.1 | 2.8e-07 | 0.06 | 0.00 | 0.95 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | LOC134466 | 0.13 | 0.09 | lasso | 4 | 0.11 | 1.8e-12 | 4.5 | -5.2 | 1.5e-07 | 0.06 | 0.00 | 0.96 | FALSE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | LOC134466 | 0.17 | 0.04 | enet | 8 | 0.08 | 1.7e-08 | 4.5 | -5.3 | 1.3e-07 | 0.08 | 0.00 | 0.96 | TRUE |
| 7 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SLC6A7 | 0.07 | 0.02 | lasso | 7 | 0.04 | 9.3e-05 | 3.3 | 5.3 | 8.7e-08 | 0.49 | 0.14 | 0.69 | TRUE |