Best TWAS P=4.23e-10 · Best GWAS P=6.58e-11 conditioned to 0.00282
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | MED8 | 0.07 | 0.00 | enet | 8 | 0.01 | 4.5e-02 | 4.5 | 5.1 | 3.0e-07 | 0.63 | 0.38 | 0.39 | FALSE |
| 2 | GTEx | Nerve Tibial | MED8 | 0.13 | 0.07 | enet | 11 | 0.16 | 3.6e-11 | 4.6 | 6.2 | 4.2e-10 | 0.71 | 0.85 | 0.14 | TRUE |
| 3 | The Cancer Genome Atlas | Rectum Adenocarcinoma | HYI | 0.23 | 0.08 | blup | 34 | 0.14 | 3.1e-04 | -4.1 | -5.3 | 1.5e-07 | -0.49 | 0.02 | 0.43 | FALSE |