Hub : Genes

MED8

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0380	0.0170	4.6e-03	0.004	0.012	-0.002	0.011	0.004	1.0e-01	1.1e-02	9.1e-01	0.014	1.0e-01
2	GTEx	Adipose Subcutaneous	0.0670	0.0280	1.2e-03	-0.001	NA	0.010	NA	0.008	4.3e-01	NA	4.6e-02	NA	6.2e-02
3	GTEx	Artery Aorta	0.1020	0.0390	1.2e-03	0.050	NA	0.078	NA	0.059	9.7e-04	NA	4.6e-05	NA	3.4e-04
4	GTEx	Brain Cortex	0.3160	0.1060	5.5e-03	-0.007	NA	0.005	NA	-0.008	5.5e-01	NA	2.3e-01	NA	6.3e-01
5	GTEx	Esophagus Mucosa	0.0710	0.0390	8.3e-03	0.004	NA	0.005	NA	-0.001	1.7e-01	NA	1.3e-01	NA	4.0e-01
6	GTEx	Heart Left Ventricle	0.0759	0.0348	4.8e-03	0.013	NA	-0.002	NA	0.008	6.6e-02	NA	4.4e-01	NA	1.2e-01
7	GTEx	Muscle Skeletal	0.2306	0.0427	0.0e+00	0.370	NA	0.335	NA	0.369	4.4e-38	NA	7.4e-34	NA	7.7e-38
8	GTEx	Nerve Tibial	0.1311	0.0365	6.5e-07	0.074	NA	0.156	NA	0.153	6.2e-06	NA	3.6e-11	NA	5.6e-11
9	GTEx	Skin Not Sun Exposed Suprapubic	0.1490	0.0520	1.0e-03	0.029	NA	0.031	NA	0.040	9.9e-03	NA	7.5e-03	NA	2.9e-03
10	GTEx	Testis	0.2150	0.0600	4.6e-06	0.135	NA	0.193	NA	0.205	1.4e-06	NA	5.8e-09	NA	1.8e-09
11	GTEx	Thyroid	0.0760	0.0340	1.1e-03	0.072	NA	0.038	NA	0.061	3.5e-06	NA	6.6e-04	NA	2.0e-05
12	TCGA	Bladder Urothelial Carcinoma	0.0270	0.0210	9.7e-03	0.003	0.014	0.002	NA	0.006	1.7e-01	2.1e-02	2.0e-01	NA	8.6e-02
13	TCGA	Head and Neck Squamous Cell Carcinoma	0.0229	0.0143	8.2e-04	0.027	0.022	0.024	NA	0.021	4.1e-04	1.6e-03	9.0e-04	NA	1.7e-03
14	TCGA	Lung Adenocarcinoma	0.0177	0.0130	7.3e-03	0.018	0.014	0.012	NA	0.014	3.1e-03	7.5e-03	1.3e-02	NA	8.4e-03
15	TCGA	Lung Squamous Cell Carcinoma	0.0257	0.0171	3.2e-03	0.014	0.014	0.003	NA	0.015	8.8e-03	8.7e-03	1.2e-01	NA	6.2e-03
16	TCGA	Testicular Germ Cell Tumors	0.2560	0.1020	3.2e-08	0.184	0.245	0.239	NA	0.232	4.6e-07	3.6e-09	5.8e-09	NA	1.0e-08

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Bipolar Disorder (2018)	1.0	1.5	3.4	-1.7	-1.3	-1.8	-0.1	0.2	1.5	1.5	-1.5	0.3	1.0	-1.4	1.2	1.1	1.4	0.9	1.0
Bipolar Disorder or Schizophrenia	5.3	13.0	23.4	-4.8	-4.0	-4.1	-0.4	0.3	4.0	4.1	-4.4	-0.3	4.2	-4.0	4.0	3.2	3.4	3.6	3.8
Depressed Affect (Nagel 2018)	0.2	0.3	2.4	1.0	0.2	0.4	-0.1	0.6	-0.0	0.3	0.5	-1.6	0.2	-0.2	-0.7	-0.3	-0.0	0.1	0.2
Depression (Nagel 2018)	0.6	0.9	3.0	-1.1	-0.5	-1.2	0.3	0.2	1.7	0.9	-0.9	-0.2	1.1	-0.9	0.9	0.9	0.7	1.1	1.1
Intelligence (Savage-Jansen 2018)	4.7	14.5	33.2	3.9	4.4	3.4	-2.9	1.7	-5.8	-3.1	5.0	0.9	-4.4	3.0	-3.7	-4.0	-3.0	-4.5	-4.5
Neuroticism (Nagel 2018)	1.0	2.3	5.8	2.4	1.5	1.7	-0.3	0.0	-2.1	-1.1	2.1	-1.6	-0.9	1.2	-2.0	-1.6	-1.4	-0.9	-0.9
Schizophrenia (2018)	6.5	13.5	23.4	-4.8	-4.2	-3.9	-0.4	0.2	4.0	4.0	-4.4	-0.6	4.6	-3.9	4.2	3.3	3.3	3.9	4.0
Schizophrenia vs Biploar Disorder	1.8	2.3	6.6	-2.6	-1.3	-1.7	-0.3	-1.4	-0.2	1.5	-1.1	-0.5	2.2	-1.5	2.0	1.2	1.1	1.7	1.9
Worry (Nagel 2018)	1.1	2.3	7.0	2.5	1.5	1.6	0.3	0.6	-2.6	-1.0	2.6	-0.4	-1.2	1.1	-1.6	-1.3	-1.0	-1.2	-1.1
Alzheimer’s Disease (in mother)	0.8	0.9	5.1	-1.6	-0.0	-0.3	-0.2	-2.3	0.2	0.7	-0.4	-1.8	0.6	-0.7	0.4	0.6	0.6	0.7	0.7
Alzheimer’s Disease (in father)	0.3	0.3	1.3	0.1	0.4	0.2	-1.1	0.6	-0.9	-0.0	-0.4	0.4	-0.6	-0.0	-0.4	-0.3	0.2	-0.8	-0.7
Alzheimer’s Disease (including proxy)	0.3	0.4	2.6	-1.1	0.1	0.0	-0.6	-1.6	0.0	0.6	-0.4	-1.0	-0.0	-0.6	-0.0	0.4	0.7	-0.0	0.0
Crohns Disease (2017)	0.6	1.3	3.8	-0.8	-1.2	-1.0	0.8	0.1	0.0	0.9	-1.5	0.3	1.8	-0.9	1.3	1.1	0.4	1.9	1.7
Irritable Bowel Disease (IBD)	0.7	1.7	3.7	-1.2	-1.0	-1.9	0.8	-0.4	0.5	1.5	-1.2	-0.2	1.9	-1.5	1.3	1.1	1.0	1.7	1.9
Ulcerative Colitis (UC)	0.7	1.4	5.0	-1.0	-0.4	-2.2	0.7	-0.6	0.8	1.7	-0.7	-0.4	1.4	-1.6	1.0	0.8	1.2	1.1	1.5
Major Depression (MDD)	1.3	1.6	4.8	-0.1	-1.7	-1.1	-0.3	1.8	1.4	1.6	-1.5	2.2	0.8	-1.6	0.7	0.5	1.5	0.1	0.9
Reaction Time	0.9	1.7	4.9	-0.2	1.5	0.9	0.2	-1.7	-1.9	-1.6	0.0	-0.5	-0.7	1.7	-1.4	-1.5	-2.2	-0.5	-1.3
Verbal and Numeric Reasoning (VNR)	4.1	9.9	19.9	2.8	3.4	3.4	-1.8	1.7	-4.5	-2.8	3.9	0.3	-3.8	2.8	-3.0	-3.3	-2.7	-3.7	-3.9
Breast Cancer	1.0	2.4	6.2	-0.9	-1.8	-2.2	-0.7	0.4	0.3	1.2	-2.5	0.5	1.9	-1.2	2.1	1.6	1.1	2.0	1.9
Ovarian Cancer	1.1	1.5	6.5	1.3	0.3	0.8	-2.1	-1.7	-2.6	-0.9	1.3	-0.9	0.4	0.8	-0.3	-0.9	-1.4	0.3	-0.3
Prostate Cancer	0.6	0.8	1.8	0.1	-1.1	-0.4	-0.5	-0.3	-0.1	1.3	0.0	0.6	1.2	-1.4	1.1	0.8	1.3	0.9	1.1
Age at First Birth	1.4	2.1	4.2	2.1	1.4	1.8	0.8	-0.0	-1.0	-1.7	2.0	0.6	-1.6	1.6	-1.3	-1.3	-1.5	-1.3	-1.5
Bipolar Disorder (2011)	0.9	0.8	2.1	0.3	-0.9	-1.1	-0.5	1.5	0.3	1.2	-0.5	-0.2	0.9	-1.2	0.8	0.9	1.1	0.9	0.9
Body Mass Index (BMI) (2010)	0.2	0.2	1.9	0.3	0.2	-0.1	0.2	0.3	-0.7	-0.2	-0.2	1.4	0.3	0.2	-0.4	-0.5	-0.6	0.2	-0.0
Coronary Artery Disease (CAD)	4.6	5.5	8.8	1.8	2.8	2.3	0.1	1.4	-1.0	-2.9	1.9	1.2	-2.8	3.0	-2.7	-3.0	-2.8	-2.7	-2.8
Crohns Disease (2012)	2.1	3.4	7.0	-1.7	-2.5	-2.4	-0.2	0.7	0.6	1.5	-2.4	0.7	2.6	-1.5	2.5	1.8	0.9	2.6	1.9
Mean Putamen Volume	0.4	0.4	1.4	-0.9	0.1	-0.3	1.2	1.0	1.0	0.5	-0.7	0.5	0.5	-0.5	0.6	0.5	0.5	0.3	0.4
Fasting Glucose	0.5	0.6	1.7	-0.3	1.1	1.3	-0.6	0.2	-1.1	-0.1	1.3	-0.2	-0.8	0.2	-0.8	-1.0	-0.2	-1.1	-0.8
HbA1C	0.2	0.2	1.2	-1.1	-0.1	-0.1	0.2	-0.6	0.0	-0.1	-1.0	0.0	0.0	0.1	0.2	0.4	0.1	0.2	0.1
HDL Cholesterol	0.3	0.5	1.2	0.6	-0.5	-0.5	-0.0	1.1	-0.3	1.1	0.3	0.9	0.4	-1.1	0.4	0.6	1.1	0.3	0.7
LDL Cholesterol	0.2	0.3	1.2	-0.7	0.6	-0.4	0.0	-0.3	1.1	0.7	-0.6	0.0	-0.1	-0.7	0.3	0.8	0.9	0.0	0.4
Lupus	0.4	0.6	2.6	-0.3	1.2	0.3	0.7	-0.1	-0.5	-0.4	0.2	-0.6	-1.3	0.4	-0.9	-0.9	-0.0	-1.6	-1.1
Neuroticism (2016)	1.9	2.8	5.2	1.9	0.7	1.8	-2.1	0.6	-2.0	-1.9	1.7	-1.0	-1.1	2.0	-1.7	-2.3	-2.0	-1.2	-1.5
Primary Biliary Cirrhosis	0.6	0.9	2.5	1.0	0.7	-0.1	-0.2	1.4	-1.4	-0.9	1.1	1.6	-0.9	0.9	-0.9	-0.5	-0.8	-0.6	-0.7
Rheumatoid Arthritis	0.3	0.4	3.0	-1.7	-0.1	-0.5	0.0	-1.2	0.3	0.1	-0.9	0.3	0.6	-0.1	0.5	0.0	-0.2	0.4	0.4
Schizophrenia (2014)	4.5	10.0	19.4	-4.4	-3.8	-3.4	-0.5	-0.2	3.0	3.5	-3.8	-0.4	3.6	-3.4	4.0	2.9	3.1	2.9	3.2
Triglycerides	0.4	0.6	3.9	-0.5	0.6	0.4	2.0	-1.8	1.0	-0.1	-0.1	-0.2	-0.6	0.1	-0.3	-0.1	0.0	-0.5	-0.5
Type 2 Diabetes (T2D) (2012)	0.7	0.8	4.2	-1.7	-0.4	-0.4	0.4	-2.0	1.3	0.4	-0.8	-0.4	0.3	-0.4	0.6	0.8	0.5	0.6	0.6
Ulcerative Colitis	1.2	1.7	7.6	-1.3	-0.4	-2.8	0.5	0.3	0.8	1.7	-1.3	1.6	1.3	-1.8	1.1	0.8	1.4	0.8	1.0
Blood Eosinophil Count	0.2	1.6	5.3	-1.8	-0.0	1.0	0.1	-2.2	-2.3	-1.3	0.6	-1.2	0.3	1.3	-0.2	-1.5	-1.9	-0.1	-0.1
Blood Platelet Count	0.5	5.2	11.3	-2.5	0.7	0.7	-2.7	-2.7	-2.8	-2.0	1.5	-2.7	-1.9	2.0	1.0	-2.8	-2.0	-3.4	-3.0
Blood Red Count	3.5	33.4	79.6	4.3	5.8	6.5	-3.3	0.2	-8.9	-6.8	6.5	-0.2	-4.7	6.8	-6.0	-7.1	-7.5	-4.6	-5.3
Blood White Count	2.2	16.4	31.0	4.0	3.4	4.8	-0.2	0.3	-3.0	-5.2	5.3	0.9	-3.8	5.3	-4.1	-5.0	-5.6	-3.8	-4.2
Heel T-Score	0.1	1.0	6.2	-1.2	-0.6	-0.1	2.5	-0.2	1.8	0.7	-1.2	-1.3	0.2	-0.6	0.2	0.3	0.6	-0.1	0.1
BMI	0.8	4.6	8.2	2.0	1.9	2.0	0.0	0.7	-0.7	-2.7	2.1	0.9	-2.3	2.7	-2.9	-2.9	-2.7	-2.4	-2.5
Height	1.3	25.2	49.1	2.9	7.0	5.7	1.6	-1.5	-5.1	-5.7	5.1	-0.9	-5.6	5.6	-6.0	-5.7	-5.4	-5.0	-6.0
Waist Hip Ratio (WHR)	0.5	2.2	9.5	-2.3	-0.4	0.8	1.8	-3.1	2.2	-0.8	-0.6	-3.1	-0.6	0.8	0.0	0.0	-0.5	-0.5	-0.3
Systolic Blood Pressure	10.9	54.4	79.7	6.7	8.0	7.6	1.9	0.3	-6.2	-8.9	8.9	0.5	-8.1	8.8	-8.5	-8.8	-8.7	-8.0	-8.4
Smoking Status	3.5	8.5	28.4	-5.3	-3.3	-2.6	0.5	-2.1	5.2	2.3	-4.4	-1.5	1.6	-2.3	2.4	2.4	2.7	1.3	1.8
Allergy or Eczema	0.1	0.3	1.1	0.7	0.4	0.2	0.8	-1.0	1.1	0.3	0.7	0.2	-0.4	-0.3	-0.1	-0.4	0.3	-0.7	-0.6
Cardiovascular Disease	3.6	12.0	18.2	3.1	3.7	3.6	0.6	-0.3	-2.7	-4.2	4.2	0.4	-4.3	4.2	-4.0	-3.7	-3.7	-4.0	-4.1
Hypothyroidism (self reported)	2.6	6.0	10.5	2.4	2.7	2.4	-1.1	-0.8	-2.5	-2.8	2.3	-1.0	-2.3	2.7	-2.8	-3.2	-2.9	-2.6	-3.1
Respiratory disease	0.7	1.6	2.8	0.0	0.7	1.5	-1.2	-0.7	0.1	-1.6	1.0	-1.2	-1.5	1.5	-1.3	-1.7	-1.4	-1.6	-1.7
Type 2 Diabetes (T2D) (2018)	0.7	1.4	2.6	0.5	-0.6	-1.2	0.2	1.6	0.9	1.5	0.3	1.4	1.4	-1.5	1.1	1.3	1.3	1.3	1.4
Lung FEV1/FVC ratio	0.1	0.6	1.5	0.3	0.9	1.2	-0.6	0.1	0.0	-0.7	0.3	-0.4	-0.9	0.8	-0.8	-1.2	-0.8	-1.1	-1.2
Lung FVC	0.2	0.9	5.2	-0.4	-0.0	-0.7	-2.3	-1.1	0.0	0.4	-0.6	-0.6	1.5	-0.4	0.9	0.3	-0.3	1.6	0.8
Neuroticism	0.9	2.2	6.2	2.5	1.5	1.6	-0.5	0.9	-2.4	-1.0	2.2	-0.5	-0.8	1.0	-1.9	-1.6	-1.3	-0.8	-0.9
Chronotype (morning person)	0.9	2.0	6.8	1.2	1.6	0.6	-1.7	-0.3	-2.6	-1.7	1.8	-0.2	-1.1	1.7	-1.5	-1.0	-1.7	-0.5	-0.9
Hair Pigment	0.0	0.8	2.2	1.0	0.2	0.3	-1.5	-1.3	0.3	-0.5	0.3	-1.1	-1.0	0.5	-0.9	-1.1	-0.4	-1.4	-1.1
Tanning	0.3	3.6	8.8	-2.4	-2.0	-1.9	-1.0	-1.1	1.1	1.4	-3.0	-0.9	2.6	-1.3	1.9	1.8	0.8	2.8	2.4
Hand grip strength (left)	0.2	0.4	2.0	-0.4	0.1	0.6	0.2	-0.8	1.4	-0.9	0.1	-0.9	-0.3	0.9	-0.1	-0.1	-0.8	0.1	-0.6
Number of treatments/medications taken	1.9	3.3	6.8	1.6	2.0	1.7	-0.4	-0.7	-1.0	-2.0	1.2	-1.3	-2.2	2.0	-2.6	-2.2	-1.8	-2.3	-2.5
Average weekly spirits intake	1.2	1.5	7.2	-2.7	-0.9	-1.7	-0.0	-0.5	0.8	0.1	-2.5	0.8	1.0	-0.1	1.0	0.7	0.1	1.2	0.7
Sensitivity / hurt feelings	0.8	1.3	4.2	1.1	0.8	1.7	0.2	-0.3	-0.9	-1.5	0.5	-1.0	-0.4	1.6	-1.4	-1.6	-2.1	-0.3	-1.0
Frequency of depressed mood in last 2 weeks	0.6	0.9	1.7	-0.7	-0.7	-0.3	0.2	0.5	1.1	1.3	-0.6	-0.6	1.3	-1.2	1.1	0.9	1.1	1.1	1.3
Hearing difficulty/problems: Yes	1.6	2.5	4.9	-1.7	-1.8	-2.2	-0.2	-1.2	0.6	2.0	-1.4	-0.5	1.9	-2.0	2.0	1.4	1.8	1.3	1.5
Relative age of first facial hair	3.8	7.7	18.8	-3.5	-2.9	-2.8	0.2	-0.7	2.8	2.4	-4.3	-1.1	3.4	-2.4	2.8	2.9	2.1	3.6	3.2
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	2.6	-1.1	-0.4	-0.7	-1.3	-1.6	-0.5	-0.2	-0.6	0.1	0.5	0.2	-0.2	-0.8	-0.7	-0.0	-0.3
Ever used hormone-replacement therapy (HRT)	1.4	1.8	3.7	0.1	1.1	1.6	-0.1	-0.9	0.5	-1.6	1.1	0.7	-1.6	1.6	-1.9	-1.6	-1.5	-1.6	-1.8
Ever had hysterectomy (womb removed)	0.5	0.5	3.7	-0.9	-0.3	0.2	-0.7	-1.9	0.3	-0.3	-0.1	-1.3	-0.5	0.3	-0.3	-0.3	0.1	-0.8	-0.7
Systolic blood pressure, automated reading	7.8	22.5	38.7	4.2	4.4	4.6	-0.1	-0.2	-4.7	-5.7	5.5	0.7	-4.9	5.7	-5.5	-6.2	-5.9	-5.3	-5.3
Eye problems/disorders: Diabetes related eye disease	0.7	0.7	2.8	-0.6	0.4	-1.0	1.7	-0.6	1.1	0.9	-0.8	-0.1	0.2	-1.0	0.8	0.8	1.4	0.1	0.6
Angina	4.9	6.4	10.1	0.8	1.5	2.9	0.5	-2.9	-1.8	-3.0	2.4	-2.8	-2.4	3.0	-2.9	-2.9	-3.0	-2.3	-3.2
Medication for hormone replacement therapy	2.3	2.6	7.3	-2.7	-1.3	-1.3	1.0	-1.7	2.1	1.5	-2.1	0.0	1.7	-1.4	1.2	1.4	1.2	1.8	1.7
Vitamin and mineral supplements	1.4	1.8	4.9	-0.3	-1.8	-1.1	-0.7	-0.1	0.8	1.6	-0.9	-0.3	1.6	-1.6	1.6	1.6	1.6	1.6	2.2
Supplements: Zinc	0.2	0.2	0.7	0.5	-0.7	-0.7	0.0	0.7	-0.6	0.5	-0.0	0.5	0.2	-0.6	0.2	0.2	0.9	-0.2	0.2
Medication: Co-codamol	1.4	1.7	3.8	0.2	1.3	1.0	2.0	-1.6	-0.0	-1.5	0.4	-0.8	-1.2	1.5	-1.3	-1.6	-1.7	-1.3	-1.4
Medication: Metformin	0.9	1.2	3.4	-0.5	-0.3	-1.2	0.3	-0.2	1.7	1.7	-0.8	-0.1	0.8	-1.7	1.2	1.2	1.8	0.5	1.1
Diabetes (father)	0.4	0.5	2.7	0.9	0.8	0.1	-0.1	0.6	-1.0	-0.7	1.7	0.2	-0.2	0.7	0.0	-0.8	-1.0	-0.3	-0.5
Diabetes (mother)	0.3	0.4	2.5	-0.1	0.1	0.7	-0.9	-0.6	0.8	0.0	-0.9	-1.6	0.0	0.0	-0.5	-0.7	-0.5	-0.1	-0.2
Severe depression (siblings)	1.1	1.2	3.6	0.9	1.4	1.9	0.4	0.3	-0.8	-0.9	1.2	-0.3	-1.6	0.8	-1.2	-0.9	-0.6	-1.4	-1.3
Pack years adult smoking proportion	2.3	3.6	10.9	-1.8	-1.6	-2.2	0.6	0.2	3.3	2.0	-2.7	0.4	1.9	-2.0	1.7	1.8	1.9	1.6	2.0
Impedance of leg (right)	0.1	0.6	4.0	-2.0	-0.9	0.5	-0.1	-1.3	0.7	-0.1	-1.3	0.0	0.1	0.1	0.5	0.5	0.1	0.4	0.3
Leg fat-free mass (left)	1.3	7.0	10.5	2.1	2.7	2.9	0.6	0.0	-2.0	-3.2	3.2	-0.5	-3.0	3.1	-3.1	-3.2	-3.1	-3.0	-3.2
Trunk fat percentage	0.7	2.7	6.9	-0.1	1.0	1.7	0.2	0.7	-0.6	-1.9	1.1	1.0	-2.0	1.8	-1.9	-2.6	-2.0	-2.6	-2.2
Hand grip strength (right)	0.3	0.7	2.3	0.0	0.3	1.2	-1.1	-0.5	0.4	-1.3	0.7	-0.9	-0.4	1.4	-0.5	-0.7	-1.5	-0.0	-0.8
Townsend deprivation index at recruitment	3.6	5.1	11.2	-2.5	-2.1	-3.1	-0.0	-0.7	3.3	2.2	-2.8	-1.2	2.2	-2.2	2.0	2.4	2.3	2.1	2.6
Current tobacco smoking	3.8	6.2	14.5	-3.4	-2.1	-3.0	-0.6	0.6	3.4	2.7	-3.8	-0.5	2.3	-2.7	2.4	2.2	2.7	1.8	2.3
Average weekly fortified wine intake	0.4	0.5	3.3	-1.8	-0.0	-0.2	0.7	-1.2	0.7	0.4	0.4	-0.1	-0.2	-0.4	0.4	0.7	0.8	-0.1	0.3
Maternal smoking around birth	6.8	9.8	20.5	-4.5	-2.9	-2.6	1.7	-3.1	4.5	3.0	-4.4	-2.6	2.7	-3.1	3.0	2.6	3.1	2.1	2.5
Fed-up feelings	0.5	0.8	2.7	-0.0	-0.8	-0.9	-0.3	1.0	0.6	0.9	-0.7	-0.9	1.6	-0.9	0.9	0.5	0.4	1.4	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	3.3	4.5	9.9	-3.1	-1.4	-1.4	0.5	-1.1	3.0	1.8	-2.1	-1.4	2.9	-1.8	2.3	2.0	1.2	2.9	2.6
Relative age voice broke	2.5	3.8	11.6	-3.0	-2.0	-1.4	0.6	-0.5	3.2	1.1	-3.4	-0.1	2.1	-1.2	1.8	1.8	0.9	2.3	1.9
Taking other prescription medications	0.2	0.3	0.9	0.4	-0.1	-0.0	-0.4	-0.3	-0.1	-0.4	-0.0	-0.9	-0.5	0.4	-0.5	-1.0	-0.4	-1.0	-0.8
Age when periods started (menarche)	7.7	18.5	44.3	-4.6	-4.6	-4.8	0.1	0.8	6.7	4.1	-6.1	0.7	4.8	-4.1	4.6	4.1	3.9	4.7	4.1
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	3.2	0.4	0.4	0.5	-1.8	-0.5	-0.4	-0.9	0.7	-0.3	-1.1	0.9	-1.0	-1.0	-0.7	-1.4	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	4.3	-0.7	-0.0	0.9	0.6	-2.1	0.7	-0.4	-0.2	-1.3	-0.2	0.5	-0.6	0.1	-0.4	0.2	-0.3
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	1.6	1.3	-0.5	-0.5	-1.2	1.2	0.1	0.6	1.0	1.1	0.7	-0.6	0.9	1.0	0.5	0.9	0.9
Qualifications: CSEs or equivalent	1.9	2.5	5.7	-1.2	-2.4	-2.0	0.9	-1.4	1.6	0.9	-1.9	-1.4	2.0	-0.9	1.9	1.3	0.8	2.0	1.9
Serious illness, injury or assault to yourself	0.5	0.6	2.7	-0.7	0.9	0.7	0.5	-0.6	-1.7	0.3	0.5	0.2	-0.7	-0.3	-0.7	-0.7	0.2	-1.1	-1.2
High blood pressure	4.5	12.5	19.8	3.0	3.1	3.2	0.0	-0.3	-3.4	-4.2	4.0	0.2	-4.4	4.2	-4.3	-4.1	-3.9	-4.2	-4.5
Hayfever, allergic rhinitis or eczema	0.1	0.3	1.3	0.3	-0.2	-0.1	0.8	-1.1	1.1	0.6	0.2	-0.7	-0.1	-0.6	0.2	-0.2	0.5	-0.5	-0.3
Multivitamins +/- minerals	0.6	0.7	1.9	-1.2	0.9	0.1	0.7	-1.4	-0.3	-0.5	0.2	-0.3	-0.8	0.5	-0.8	-1.2	-0.5	-1.3	-1.4
Stomach or abdominal pain in last month	0.2	0.2	0.8	0.5	0.4	-0.4	-0.9	0.4	0.8	0.5	0.4	-0.3	0.2	-0.5	0.2	-0.3	0.5	-0.1	0.0
Supplements: Glucosamine	0.4	0.5	1.8	1.0	1.3	-0.1	-0.2	0.5	-0.1	-0.6	0.4	-0.0	-0.4	0.6	-1.0	-1.1	-0.8	-0.4	-0.9
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	3.0	-0.1	-1.0	-0.6	0.6	1.5	1.4	1.2	-0.6	1.7	0.8	-1.1	1.1	0.9	1.4	0.5	1.1
Medication: Atenolol	2.6	3.3	6.4	2.5	1.4	1.2	0.4	2.3	-1.3	-1.7	2.2	1.8	-1.7	1.7	-2.1	-2.2	-1.8	-1.8	-1.9
Medication: Levothyroxine sodium	2.4	4.0	7.2	1.1	2.0	2.1	-0.1	-1.1	-1.6	-2.7	1.6	-1.1	-2.1	2.6	-2.2	-2.5	-2.6	-2.0	-2.7
Sitting height	2.5	17.5	39.1	4.3	5.1	5.0	0.1	-0.5	-4.5	-3.8	6.2	-1.1	-4.8	3.8	-4.8	-4.5	-3.5	-4.7	-4.5
Chronic bronchitis/emphysema (father)	0.3	0.4	1.8	-0.1	-0.5	-0.3	-1.4	1.4	0.3	0.6	-0.4	0.5	0.7	-0.6	0.4	0.2	0.5	0.5	0.4
High blood pressure (mother)	7.2	10.1	18.5	4.0	3.4	3.5	0.0	1.5	-2.6	-2.9	3.4	1.4	-4.1	3.0	-3.6	-3.6	-2.5	-4.3	-3.8
Body mass index (BMI)	0.4	1.5	3.3	1.4	0.7	0.7	-0.3	1.6	0.2	-1.3	0.7	1.2	-1.2	1.3	-1.4	-1.8	-1.5	-1.7	-1.4
Impedance of leg (left)	0.1	0.4	2.2	-1.5	-0.7	0.3	-0.0	-0.9	0.5	0.1	-1.1	0.4	0.3	-0.1	0.5	0.4	0.2	0.5	0.4
Leg predicted mass (left)	1.3	6.9	10.4	2.1	2.7	2.8	0.5	0.1	-2.1	-3.1	3.2	-0.5	-3.0	3.1	-3.0	-3.1	-3.0	-2.9	-3.2
Trunk fat mass	1.1	4.6	10.0	0.5	1.6	2.3	0.5	0.5	-1.0	-2.5	1.8	0.8	-2.6	2.5	-2.5	-3.2	-2.5	-3.2	-2.8
Waist circumference	0.7	2.6	6.2	0.7	0.7	1.5	0.8	0.0	0.3	-2.0	1.1	0.7	-2.1	2.0	-1.9	-2.3	-2.0	-2.5	-2.2
Number of incorrect matches in round	1.8	3.0	6.1	-1.6	-1.4	-1.5	2.1	-0.8	1.9	1.4	-1.7	1.7	2.5	-1.3	2.0	1.6	1.0	2.3	2.2
Past tobacco smoking	1.1	2.0	10.6	3.2	1.0	0.8	0.2	1.1	-3.2	-0.5	2.3	1.2	-0.3	0.5	-1.0	-0.6	-0.6	-0.1	-0.2
Alcohol usually taken with meals	12.3	19.9	29.3	4.5	5.0	4.6	-3.0	-0.4	-5.2	-4.3	5.3	-1.8	-5.4	4.3	-5.4	-4.5	-4.0	-5.0	-5.3
Nervous feelings	0.8	1.4	8.2	2.3	1.1	1.2	0.8	0.1	-2.9	-0.4	1.9	0.2	0.0	0.4	-0.6	-1.0	-0.7	-0.0	-0.0
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	3.1	-0.9	-0.8	-0.7	1.2	-1.0	1.8	1.0	-0.9	-0.7	1.5	-1.0	1.2	1.0	0.7	1.4	1.5
Hearing difficulty/problems with background noise	0.5	0.8	2.2	-0.2	-0.9	-1.5	-1.2	0.7	-0.4	0.9	-0.8	0.0	1.4	-0.9	0.8	0.3	0.5	1.0	0.8
Hair/balding pattern: Pattern 2	0.1	0.1	0.5	-0.1	0.3	-0.1	-0.2	-0.7	-0.4	0.1	0.7	-0.7	-0.5	-0.1	0.1	0.2	0.4	-0.5	-0.2
Had menopause	2.1	2.6	4.9	0.6	1.2	1.6	0.3	-1.7	-0.8	-2.1	1.2	-0.5	-1.7	2.1	-2.2	-2.2	-2.2	-1.6	-1.8
Had other major operations	4.7	5.7	12.9	3.6	2.9	2.2	-1.3	1.2	-2.7	-1.9	3.1	0.3	-2.7	1.8	-2.9	-2.2	-1.8	-2.6	-2.8
Forced vital capacity (FVC)	0.6	2.2	5.2	0.7	1.6	2.3	-1.9	-1.0	-1.2	-1.9	1.7	-1.3	-0.7	1.9	-1.0	-1.2	-2.2	-0.0	-1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	2.3	-0.3	-0.8	0.5	0.2	-1.5	0.6	-0.4	-0.2	-0.7	-0.2	0.5	-0.3	0.3	-0.3	0.1	-0.1
Ever unenthusiastic/disinterested for a whole week	1.7	2.1	5.0	-2.2	-0.8	-0.7	1.0	-1.1	1.3	1.6	-2.2	-0.8	1.4	-1.6	1.3	1.6	1.6	1.3	1.4
Qualifications: None of the above	8.5	18.1	42.8	-5.0	-4.1	-5.3	-0.2	-1.3	5.9	3.9	-6.5	-1.6	5.1	-3.9	4.5	3.4	3.0	4.3	4.7
Financial difficulties in last 2 years	0.6	0.8	2.8	-0.8	-1.0	-0.5	0.7	0.6	1.7	0.8	-1.4	1.5	0.5	-0.8	0.9	0.4	1.0	0.3	0.5
Mouth/teeth dental problems	1.8	2.8	4.8	1.9	1.0	2.2	-1.0	-0.7	-2.0	-1.8	2.2	-0.1	-2.0	1.8	-2.0	-1.3	-1.6	-1.4	-2.0
Heart attack	1.5	1.9	4.3	0.7	1.5	1.4	0.4	0.0	-1.5	-1.6	0.4	0.2	-1.8	1.6	-1.8	-1.5	-1.5	-1.7	-2.1
Allergy	0.2	0.6	3.0	-0.3	0.2	-0.2	0.3	1.6	-1.3	-0.0	-0.3	1.7	0.5	0.1	0.1	0.4	-0.1	0.8	0.6
Pain all over the body in last month	1.9	2.1	4.9	-0.7	-2.2	-1.9	-1.4	0.9	0.9	1.6	-2.0	0.5	1.3	-1.6	1.4	1.6	1.5	1.1	1.3
Diabetes (self-reported)	1.5	2.3	4.5	0.0	-1.0	-2.0	0.8	1.0	1.8	2.1	-0.8	0.8	1.7	-2.0	1.5	1.6	1.9	1.5	1.7
Hayfever/allergic rhinitis (self-reported)	2.3	3.0	6.2	-1.4	-2.3	-1.8	0.5	-0.1	2.5	1.5	-1.9	0.8	2.0	-1.5	1.9	2.2	1.3	2.3	1.9
Medication: Ramipril	2.4	3.1	6.3	0.8	1.8	2.3	-0.1	0.0	-1.1	-1.9	1.9	-0.7	-2.3	1.8	-2.1	-1.8	-1.3	-2.5	-2.5
Medication: Simvastatin	0.7	1.0	3.7	-0.5	-1.9	-1.5	-0.7	-0.1	0.6	1.0	-1.4	-0.3	0.8	-1.0	1.1	0.7	1.2	0.4	0.7
Fluid intelligence score	4.6	9.5	25.9	3.2	3.2	3.3	-1.5	0.8	-5.1	-2.2	4.8	0.4	-3.7	2.3	-3.0	-2.7	-2.1	-3.4	-3.5
Illnesses of siblings	0.7	0.9	3.6	-0.4	-0.5	-1.2	-1.9	1.3	0.2	0.7	-0.5	0.2	0.4	-0.7	1.3	1.6	0.6	1.1	0.9
Neuroticism score	0.2	0.4	0.9	0.9	-0.1	0.7	0.0	0.9	-1.0	-0.1	0.4	-0.8	0.8	0.2	-0.4	-0.3	-0.6	0.8	0.5
Weight	1.6	7.8	14.0	2.3	2.5	2.9	0.4	1.0	-1.6	-3.4	2.9	0.8	-3.2	3.3	-3.4	-3.7	-3.4	-3.4	-3.4
Impedance of arm (right)	0.2	0.8	6.6	-2.6	-0.3	0.5	-0.2	-1.0	-0.9	-0.8	-0.4	-1.0	-0.4	0.8	0.3	0.1	-0.6	0.1	-0.4
Arm fat percentage (right)	0.5	1.8	4.1	-0.1	0.6	1.1	-0.2	0.7	-0.3	-1.8	0.4	0.7	-1.5	1.8	-1.5	-2.0	-2.0	-1.9	-1.8
Trunk fat-free mass	1.2	6.8	10.7	2.7	2.8	2.8	0.3	-0.1	-2.0	-2.9	3.3	-0.4	-2.9	2.9	-3.2	-3.2	-2.8	-2.9	-3.1
Hip circumference	1.6	7.1	11.6	2.4	2.0	2.5	0.3	1.9	-1.5	-3.1	2.8	2.3	-2.9	3.1	-3.1	-3.4	-3.1	-3.1	-3.1
Time employed in main current job	1.9	2.2	4.9	1.2	0.4	1.4	-0.8	0.3	-1.8	-2.2	1.4	-0.1	-1.5	2.2	-1.4	-1.8	-2.2	-1.3	-1.6
Alcohol intake versus 10 years previously	1.9	2.9	12.0	-2.9	-2.5	-1.4	-0.3	-0.9	1.8	0.9	-3.5	-1.5	1.7	-1.0	1.6	0.6	0.5	1.3	1.0
Father’s age at death	0.2	0.2	0.7	0.7	0.1	-0.5	0.5	0.5	-0.7	0.8	-0.2	0.3	-0.1	-0.8	-0.1	0.3	0.7	-0.2	-0.1
Worrier / anxious feelings	2.1	4.0	11.6	2.8	1.6	2.3	1.2	-0.5	-3.4	-1.6	3.1	-0.5	-1.5	1.6	-2.4	-2.0	-1.6	-1.5	-1.4
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	1.4	-0.5	-0.6	-0.7	-0.1	0.2	0.9	1.0	-0.6	0.5	1.2	-1.0	0.7	1.0	0.7	1.2	1.0
Falls in the last year	0.5	0.7	1.4	-1.1	-0.5	-1.1	0.8	-0.3	0.8	0.9	-1.0	-1.0	1.2	-0.9	0.9	0.4	0.4	1.0	0.6
Hair/balding pattern: Pattern 3	1.1	1.6	5.4	2.3	1.5	0.5	0.2	0.7	-2.1	-1.0	1.6	1.4	-0.5	1.1	-1.2	-1.1	-1.6	-0.2	-0.8
Number of live births	0.2	0.4	3.9	-0.0	-0.3	-0.1	0.7	0.8	-0.0	0.1	-0.4	2.0	-0.1	-0.1	0.3	-0.3	0.0	-0.4	-0.1
Forced expiratory volume in 1-second (FEV1)	0.8	2.7	7.6	1.3	1.7	2.8	-1.6	-0.4	-1.4	-2.1	1.9	-1.0	-1.0	2.1	-1.2	-1.6	-2.4	-0.5	-1.5
Pulse rate	0.3	0.5	2.7	-0.4	0.9	0.6	-1.5	0.6	-1.6	-0.1	0.2	-0.2	0.3	0.2	-0.3	-0.7	-0.7	0.1	-0.2
Happiness	0.4	0.5	2.1	1.0	-0.1	-0.5	-0.0	1.4	-0.3	0.9	-0.0	1.1	0.6	-0.9	0.4	0.2	0.7	0.5	0.6
Noisy workplace	4.2	5.2	11.5	-3.0	-2.7	-2.5	0.5	-0.2	1.2	2.5	-3.4	-0.2	2.7	-2.6	2.4	2.2	2.4	2.1	2.6
Qualifications: A levels/AS levels or equivalent	6.6	14.5	36.6	4.8	3.7	4.6	-0.6	1.6	-6.0	-2.5	6.0	1.9	-4.5	2.6	-3.7	-3.2	-1.9	-4.3	-4.0
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	3.5	1.3	0.2	-0.0	-1.2	0.7	-1.9	0.8	1.6	0.2	-0.3	-0.7	-0.1	-0.0	0.5	-0.5	-0.1
Mouth/teeth dental problems: Dentures	2.2	3.6	9.5	-3.1	-1.9	-2.3	0.2	0.1	1.6	1.1	-3.0	-0.6	2.8	-1.1	1.9	1.3	0.4	2.6	2.3
Asthma	0.4	0.8	2.0	-0.2	-0.2	0.9	-0.7	-1.1	0.4	-1.0	0.7	-1.4	-1.2	0.9	-1.0	-0.8	-0.5	-1.3	-1.1
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	2.7	-0.2	-0.8	-0.3	-1.6	-0.4	0.3	-0.5	0.7	-1.6	0.1	0.5	-0.0	-0.1	-0.6	0.3	0.3
Medication: Cholesterol lowering	0.2	0.3	1.3	0.1	-0.5	-0.6	0.8	0.2	0.2	0.3	-0.8	-0.1	-0.7	-0.2	-0.1	-0.0	0.9	-1.1	-0.8
Depression (self-reported)	2.7	3.2	8.4	-2.6	-2.1	-1.9	0.9	0.4	2.9	2.1	-1.8	-0.3	1.2	-2.0	1.9	1.5	2.3	0.8	1.6
Medication: Lansoprazole	1.3	1.5	4.8	-1.2	-0.2	-1.4	1.0	-0.8	1.0	1.6	-1.4	-2.2	0.7	-1.5	0.8	1.1	1.7	0.6	0.9
Prospective memory result	0.2	0.3	1.6	-0.1	-0.1	-0.3	-0.2	-0.8	1.3	0.3	-0.6	-0.9	0.3	-0.2	-0.2	0.5	0.3	0.6	0.5
Lung cancer (father)	2.9	3.4	7.3	-1.4	-1.9	-2.7	-0.9	0.5	2.4	1.8	-1.4	-0.5	2.2	-1.9	2.3	1.8	1.9	1.8	2.3
Illnesses of mother	1.7	2.1	4.5	-1.0	-1.1	-1.6	0.4	0.0	0.9	1.7	-0.7	-0.3	1.8	-1.8	1.6	2.1	1.7	2.0	2.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.2	4.8	1.2	1.6	2.1	-2.1	-0.6	-1.4	-1.8	1.9	-1.4	-0.6	1.8	-1.0	-1.2	-2.2	-0.1	-1.1
Pulse wave Arterial Stiffness index	0.6	0.7	3.4	-1.9	0.4	0.7	-0.8	-0.5	-0.2	-1.1	-0.7	-0.3	-0.7	1.0	-0.4	-0.8	-1.0	-0.7	-1.0
Impedance of arm (left)	0.1	0.5	3.7	-1.9	-0.1	0.9	0.1	-0.3	-0.8	-0.8	-0.1	0.1	-0.7	0.8	0.0	-0.1	-0.6	-0.3	-0.6
Arm fat mass (right)	1.0	4.0	8.3	1.0	1.4	1.9	0.1	0.9	-0.8	-2.5	1.5	0.9	-2.3	2.5	-2.4	-2.9	-2.7	-2.6	-2.6
Trunk predicted mass	1.2	6.8	10.8	2.6	2.8	2.8	0.2	-0.2	-2.0	-2.9	3.3	-0.5	-2.9	2.9	-3.2	-3.2	-2.9	-2.8	-3.0
Standing height	1.6	15.7	25.7	2.3	4.1	5.1	1.2	-1.4	-3.9	-4.6	5.1	-1.0	-4.6	4.6	-4.5	-4.4	-4.2	-4.0	-4.6
Length of working week for main job	0.4	0.5	1.6	0.5	1.3	0.6	-0.5	0.3	-0.9	-0.5	0.9	-0.9	-0.9	0.4	-0.5	-0.4	-0.4	-0.7	-0.7
Exposure to tobacco smoke at home	0.5	0.6	1.4	1.1	-0.6	-1.2	0.1	0.8	0.6	0.9	-0.8	0.7	0.9	-0.9	0.5	0.4	0.6	0.7	0.8
Breastfed as a baby	0.5	0.6	2.7	0.1	0.6	-0.1	-0.1	-0.0	-1.6	0.1	1.2	0.1	-0.9	-0.1	-0.5	-0.7	0.3	-1.5	-0.7
Tense / ‘highly strung’	0.2	0.4	1.2	-0.5	-0.8	-0.1	0.1	-0.5	-0.1	0.6	0.1	-1.1	1.0	-0.6	0.7	0.2	0.5	0.5	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	5.9	-1.4	-0.8	-1.1	0.1	-0.6	1.9	2.0	-1.3	-1.1	0.7	-1.9	1.1	1.3	2.4	0.1	1.0
Hair/balding pattern: Pattern 4	1.4	3.3	6.4	1.1	1.4	1.8	-0.8	0.2	-1.4	-2.5	1.5	-0.3	-2.1	2.5	-2.1	-2.4	-1.9	-2.3	-2.4
Birth weight of first child	1.1	2.0	5.0	-0.1	-1.5	-1.6	-0.2	-0.0	-0.1	1.5	-1.1	0.6	2.0	-1.4	1.8	1.9	1.1	2.2	2.1
Peak expiratory flow (PEF)	3.5	8.1	16.8	2.6	3.1	4.1	-0.5	1.3	-1.9	-3.3	3.2	-0.2	-3.3	3.2	-2.9	-2.9	-3.1	-2.9	-3.6
Pulse wave reflection index	1.5	1.9	3.6	-0.8	1.2	1.8	-0.6	-1.4	-0.6	-1.9	0.5	-0.7	-1.7	1.8	-1.2	-1.6	-1.6	-1.7	-1.7
Ever highly irritable/argumentative for 2 days	3.4	4.1	8.1	-2.8	-2.3	-1.8	-0.7	-0.1	2.3	1.9	-2.4	-0.4	2.4	-1.9	2.4	2.2	1.6	2.3	2.4
Loud music exposure frequency	0.4	0.4	2.4	0.3	-0.2	0.5	0.5	0.4	1.6	-0.7	-1.2	0.2	0.2	0.7	0.3	0.3	-0.6	0.6	0.2
Qualifications: O levels/GCSEs or equivalent	2.0	3.2	8.8	3.0	1.4	2.2	-1.8	1.7	-2.4	-1.0	2.9	1.8	-2.0	1.0	-1.2	-0.7	-0.5	-1.4	-1.6
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	4.2	-0.3	0.2	-0.1	1.2	-2.0	0.2	0.5	0.5	-0.4	-0.1	-0.6	0.1	-0.1	0.6	-0.5	0.2
Blood clot in the leg (DVT)	0.2	0.3	1.8	0.0	-0.4	-0.5	-1.4	0.9	0.4	0.3	-0.6	-0.8	0.3	-0.2	0.4	0.3	0.1	0.3	0.2
Medication: Paracetamol	0.5	0.9	6.4	-0.2	-0.0	0.4	0.6	-1.4	0.3	-1.1	0.2	-2.5	-0.5	1.1	-0.8	-0.3	-1.1	-0.3	-0.3
Headache pain in last month	0.3	0.4	3.2	0.1	1.0	-0.2	0.9	-0.8	0.5	-0.1	0.9	-1.8	-0.4	0.2	-0.4	-0.1	-0.1	-0.2	-0.2
Medication for cholesterol, blood pressure or diabetes	1.2	2.0	7.6	-1.2	-1.2	-1.0	-1.1	-0.5	0.9	1.0	-0.5	-0.4	2.3	-1.1	1.8	1.6	0.3	2.8	2.3
Glaucoma (self-reported)	0.9	1.0	4.4	2.1	0.7	0.2	0.6	-1.1	-1.2	-0.8	1.7	0.3	-0.8	0.8	-1.1	-0.5	-1.0	-0.5	-0.9
Gout (self-reported)	0.8	1.1	1.8	0.3	0.9	0.8	1.3	-1.2	-0.1	-1.2	0.6	-0.1	-1.1	1.2	-1.1	-1.2	-1.2	-1.2	-1.4
Hypothyroidism/myxoedema (self-reported)	1.1	2.2	4.4	1.5	1.3	0.9	-0.8	-0.1	-1.4	-2.1	1.2	-0.5	-1.3	2.0	-1.4	-2.0	-2.1	-1.5	-1.9
Medication: Amlodipine	1.2	1.7	3.8	0.2	1.9	1.6	0.5	-1.6	-1.0	-1.1	1.1	-1.4	-1.8	1.1	-1.8	-0.9	-0.6	-1.6	-1.5
Medication: Ventolin 100micrograms inhaler	0.4	0.5	2.4	-0.1	-1.5	0.0	-0.3	-0.6	0.7	0.5	-0.5	-1.6	0.2	-0.5	0.7	0.9	0.8	0.2	0.5
Birth weight	2.2	4.9	8.4	-0.6	-2.4	-2.7	0.2	0.1	1.7	2.8	-2.0	0.2	2.9	-2.7	2.8	2.5	2.3	2.8	2.6
Chronic bronchitis/emphysema (mother)	5.2	6.0	11.6	-2.0	-1.7	-3.4	-0.2	-0.5	1.4	3.2	-2.4	-0.9	3.0	-3.3	2.8	2.6	3.1	2.5	2.9
High blood pressure (siblings)	1.6	2.2	5.2	1.5	1.4	1.7	1.7	-0.4	-0.7	-1.3	1.5	-0.3	-1.7	1.2	-2.0	-2.0	-0.8	-2.3	-1.8
Forced vital capacity (FVC), Best measure	0.5	2.0	5.7	1.1	1.4	1.5	-2.4	-1.0	-1.5	-1.6	1.8	-1.3	-0.4	1.6	-0.9	-1.0	-2.0	0.2	-0.9
Body fat percentage	0.5	2.0	5.1	-0.2	0.5	1.3	0.0	0.9	-0.1	-1.6	0.5	1.1	-1.6	1.6	-1.6	-2.2	-1.8	-2.2	-1.9
Leg fat percentage (right)	0.5	1.7	4.3	0.2	0.3	1.1	-0.4	0.6	0.4	-1.6	0.1	0.9	-1.6	1.6	-1.5	-2.0	-1.7	-2.1	-1.8
Arm fat-free mass (right)	1.3	6.7	11.6	2.9	2.8	2.9	0.4	0.2	-1.7	-2.8	3.4	0.3	-2.8	2.8	-3.0	-3.3	-2.8	-3.0	-2.9
Exposure to tobacco smoke outside home	0.8	1.1	4.2	-1.9	-0.5	-1.3	0.7	-0.9	2.1	1.3	-0.9	0.2	0.8	-1.3	0.7	0.1	1.0	0.1	0.4
Comparative body size at age 10	3.1	8.5	14.9	-2.0	-2.7	-3.8	0.2	0.3	2.6	3.3	-3.4	0.5	3.5	-3.3	3.5	3.4	2.9	3.3	3.9
Number of full brothers	0.3	0.4	1.3	-0.4	0.3	-0.7	-0.1	0.5	-0.7	0.9	0.2	-1.0	1.1	-0.9	0.3	-0.5	0.3	0.5	0.9
Worry too long after embarrassment	2.1	3.6	10.1	1.6	1.6	2.5	-0.6	-0.8	-3.2	-2.2	1.9	-1.3	-0.8	2.2	-2.2	-2.3	-2.7	-0.7	-1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.1	3.5	-1.1	-0.4	-0.3	1.5	-1.2	1.3	1.1	-1.1	-1.9	0.2	-1.1	0.4	0.7	1.6	-0.1	0.2
Wheeze or whistling in the chest in last year	0.4	0.7	6.8	-0.9	0.1	0.1	0.9	-0.8	2.6	-0.3	-0.6	-1.3	0.1	0.3	0.2	0.5	-0.1	0.4	0.1
Number of children fathered	0.9	1.0	1.6	1.1	0.8	1.2	-0.2	0.8	-0.5	-1.0	1.2	1.1	-0.9	1.0	-0.6	-1.1	-1.2	-1.0	-1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.0	4.4	-1.4	0.2	0.4	0.4	-2.1	-0.9	-0.4	-0.2	-1.3	-1.2	0.4	-0.3	-1.1	-0.1	-1.8	-1.0
Age at first live birth	0.9	1.5	5.6	2.2	1.0	2.1	0.1	0.0	-1.6	-0.9	2.4	-1.2	-1.0	1.0	-0.8	-0.4	-0.8	-0.4	-0.6
Pulse wave peak to peak time	0.5	0.6	3.3	1.8	-0.2	-0.5	0.9	0.5	0.0	0.8	1.0	0.2	0.5	-0.7	0.2	0.6	0.8	0.5	0.8
Health satisfaction	0.2	0.2	1.0	0.5	0.4	0.3	0.0	0.1	-1.0	0.7	0.3	0.2	0.5	-0.7	0.2	-0.5	0.5	-0.3	0.3
Shortness of breath walking on level ground	0.2	0.2	0.8	-0.2	0.9	-0.6	-0.7	-0.2	0.2	-0.2	-0.6	0.1	0.4	0.2	-0.4	-0.6	-0.5	0.1	0.0
Qualifications: College or University degree	7.5	23.6	58.1	7.0	5.1	5.6	0.4	1.1	-6.4	-4.1	7.6	1.8	-5.9	4.1	-5.0	-3.7	-3.3	-5.1	-4.9
Eye problems/disorders: None of the above	0.3	0.3	1.2	0.2	-0.2	0.9	-1.0	1.1	-0.0	-0.7	0.1	0.4	-0.1	0.7	-0.3	-0.3	-0.8	0.2	-0.1
Mouth/teeth dental problems: Loose teeth	0.5	0.6	2.4	0.0	-0.3	-0.7	1.5	1.0	1.2	0.7	-0.7	0.6	0.6	-0.7	0.5	0.4	0.7	0.3	0.8
Emphysema/chronic bronchitis	0.2	0.3	1.1	0.0	-0.1	0.2	-0.6	-0.0	0.1	-0.3	-0.4	0.1	-1.0	0.3	-0.7	-0.4	0.1	-1.0	-0.9
Medication for pain relief, constipation, heartburn	1.5	2.6	12.1	-1.1	-0.7	-0.8	0.4	1.8	0.9	1.6	-1.7	3.5	1.2	-1.6	1.8	1.8	1.6	1.4	1.4
Neck or shoulder pain in last month	0.5	0.7	4.8	-0.9	-0.0	-0.8	0.5	-1.7	0.3	0.4	-0.9	-2.2	0.7	-0.4	0.5	-0.3	0.1	0.2	0.3
Medication: Blood pressure	1.8	3.1	7.7	1.0	1.7	1.7	1.7	0.2	-0.9	-1.7	1.4	0.6	-2.6	1.8	-2.3	-1.8	-1.1	-2.8	-2.6
Angina (self-reported)	4.6	6.0	9.6	0.8	1.6	2.7	0.1	-2.8	-1.9	-2.8	2.3	-2.9	-2.4	2.9	-2.8	-2.8	-2.9	-2.3	-3.1
Migraine (self-reported)	0.6	0.8	2.9	1.2	0.8	0.6	-1.2	0.1	-1.4	-0.0	1.7	-0.9	-0.6	0.1	-1.2	-0.8	-0.1	-0.6	-0.6
Medication: Ibuprofen	0.7	0.8	2.6	0.5	0.2	0.6	-1.6	-0.2	-0.5	-1.3	1.2	-1.2	-0.7	1.3	-0.8	-0.7	-1.3	-0.4	-0.4
Medication: Allopurinol	0.3	0.4	2.2	-0.1	0.5	0.3	1.5	-0.4	0.8	-0.5	-0.2	0.7	-0.4	0.5	-0.3	-0.4	-0.5	-0.6	-0.6
Medication: Omeprazole	0.3	0.4	2.3	-0.5	0.0	-1.1	0.7	-1.5	-0.0	0.1	-0.8	-0.8	-0.2	-0.1	-0.1	-0.1	0.0	-0.4	-0.3
Medication: Seretide 50 evohaler	0.5	0.6	1.4	0.8	0.6	0.3	-0.4	0.6	-0.2	-1.1	0.3	0.1	-0.4	1.0	-1.2	-1.2	-1.2	-0.4	-0.8
Mean time to correctly identify matches	1.3	2.4	7.5	-0.0	0.6	0.8	-0.4	-1.6	-2.7	-1.9	-0.2	-0.6	-1.1	2.0	-1.6	-2.1	-2.6	-1.2	-1.8
Heart disease (mother)	4.0	4.8	7.7	0.4	1.5	2.2	-0.6	-1.7	-2.2	-2.6	1.9	-2.1	-2.5	2.6	-2.7	-2.6	-2.5	-2.4	-2.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	1.3	-0.5	-0.8	0.2	-0.9	-0.4	1.1	-0.3	-0.7	-0.2	-0.1	0.3	0.3	0.1	-0.2	-0.1	-0.3
Whole body fat mass	1.0	4.1	8.7	0.7	1.5	2.2	0.4	0.7	-0.7	-2.5	1.5	0.8	-2.4	2.4	-2.5	-3.0	-2.5	-2.9	-2.6
Leg fat mass (right)	0.8	3.2	6.6	0.6	1.0	1.8	0.2	0.5	-0.2	-2.3	1.0	0.6	-2.1	2.3	-2.2	-2.6	-2.4	-2.5	-2.4
Arm predicted mass (right)	1.1	5.8	10.1	2.8	2.5	2.7	0.6	0.0	-1.5	-2.6	3.2	0.1	-2.6	2.6	-2.8	-3.1	-2.6	-2.8	-2.7
Pulse rate, automated reading	3.5	11.1	21.6	1.0	3.1	4.5	-0.6	-0.3	-3.6	-3.3	3.7	-0.6	-4.2	3.3	-4.0	-4.0	-3.0	-4.7	-4.2
Alcohol intake frequency.	3.0	7.0	13.0	-2.5	-3.0	-3.3	0.3	0.7	1.9	2.6	-3.4	0.8	3.6	-2.6	2.6	2.7	1.9	3.5	3.4
Comparative height size at age 10	4.1	22.8	40.1	3.5	5.3	5.5	0.5	-2.0	-6.2	-5.0	6.3	-1.6	-5.5	5.0	-5.3	-5.1	-4.4	-5.2	-5.3
Number of full sisters	0.5	0.6	4.0	-0.8	-0.9	-0.7	-0.9	-0.9	0.7	-0.4	-0.1	-2.0	-0.2	0.4	-0.3	-0.0	-0.3	-0.2	-0.3
Suffer from ‘nerves’	0.3	0.5	4.5	-0.6	0.4	0.8	-0.9	-0.4	-2.1	0.1	0.6	-0.6	-0.0	-0.0	-0.2	-1.0	-0.1	-0.6	-0.3
Overall health rating	0.4	0.9	1.9	-0.5	-1.2	-0.9	0.3	-0.1	1.4	1.4	-0.9	-0.6	1.1	-1.3	0.8	0.6	1.0	0.5	1.0
Chest pain or discomfort	0.3	0.4	0.9	0.9	0.8	0.2	0.8	-0.0	0.3	-0.2	0.7	0.4	-1.0	0.2	-0.6	-0.1	0.3	-0.9	-0.9
Had major operations	0.1	0.1	1.1	-0.1	-0.3	0.3	0.7	-0.4	-0.0	0.3	0.1	-1.1	0.2	-0.3	-0.2	-0.1	0.2	-0.0	0.1
Age at last live birth	0.9	1.3	4.7	1.0	0.8	2.1	0.9	-1.3	-1.3	-1.0	2.2	-1.2	-0.4	1.0	-0.4	-0.5	-1.2	0.1	-0.4
Family relationship satisfaction	0.5	0.6	2.8	0.1	-0.5	-0.2	-1.7	1.0	-0.2	1.2	-0.7	0.9	0.2	-1.2	0.1	0.1	1.1	-0.1	0.2
Leg pain on walking	0.3	0.4	2.7	-0.7	-0.1	-0.6	0.7	-0.1	1.6	-0.5	-0.8	-0.4	0.2	0.5	0.2	0.5	-0.4	0.6	0.3
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.1	2.9	-0.0	0.9	0.9	-0.7	0.6	-1.7	-1.1	0.3	-0.6	-1.3	1.1	-1.3	-1.2	-1.1	-1.4	-1.5
Commuting to job workplace: Car/motor vehicle	0.2	0.3	1.5	0.0	-0.5	-0.3	-0.4	-0.0	1.0	0.4	-1.2	0.2	0.3	-0.4	0.1	0.5	0.5	0.3	0.4
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	3.2	1.1	0.6	0.9	0.3	0.3	-0.4	-1.7	1.1	-0.5	-0.7	1.7	-0.9	-1.1	-1.8	-0.6	-1.1
Medication: Aspirin	2.3	3.0	7.0	2.1	1.1	0.6	-1.2	-1.1	-1.6	-1.4	1.6	-2.6	-1.9	1.4	-2.0	-2.1	-1.3	-2.2	-2.2
Supplements: Vitamin C	1.0	1.2	3.6	1.2	1.9	0.7	0.4	-0.6	-1.3	-1.2	1.2	-0.7	-1.2	1.2	-1.1	-0.6	-1.1	-1.0	-1.4
Knee pain experienced in last month	0.4	0.6	1.4	0.3	1.0	0.3	-0.1	0.1	0.5	-1.0	0.4	-0.4	-0.8	1.0	-1.2	-1.1	-1.2	-0.8	-1.0
Hypertension (Self-reported)	3.3	9.2	14.5	2.8	2.7	2.7	0.4	-0.1	-3.0	-3.5	3.5	0.2	-3.7	3.5	-3.7	-3.5	-3.3	-3.6	-3.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	3.8	-0.3	-0.6	-1.5	-0.5	0.8	0.9	1.9	-1.2	0.1	1.1	-1.9	1.0	1.0	1.8	0.7	1.0
Illnesses of father: Heart disease	6.8	9.4	16.6	3.1	2.9	4.1	0.8	-0.8	-2.7	-3.9	2.8	-0.2	-3.2	3.9	-3.6	-3.2	-3.9	-2.7	-3.3
Illnesses of siblings: Diabetes	0.6	0.7	2.9	-0.9	-0.7	-0.4	0.1	-0.5	0.6	1.1	-1.7	0.5	1.1	-1.1	0.2	0.2	1.1	0.5	0.6
Smoking status: Previous	0.7	1.1	5.5	-2.3	-0.7	-0.2	0.6	-1.2	2.4	-0.1	-1.8	-0.2	-0.4	0.0	0.5	0.3	0.2	-0.4	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.4	5.3	0.8	0.9	1.9	1.1	-1.9	-0.6	-2.3	1.6	-1.1	-1.7	2.3	-1.4	-1.3	-2.0	-1.0	-1.5
Whole body fat-free mass	1.2	7.0	11.6	2.7	2.8	2.8	0.4	-0.0	-2.0	-3.0	3.4	-0.5	-2.9	2.9	-3.1	-3.3	-2.9	-3.0	-3.1
Leg fat-free mass (right)	1.1	5.9	10.8	2.4	2.5	2.5	0.6	0.3	-2.0	-2.8	3.3	-0.4	-2.6	2.8	-2.8	-2.9	-2.8	-2.6	-2.8
Arm fat percentage (left)	0.7	2.6	5.8	0.3	0.8	1.6	-0.0	1.0	-0.4	-2.2	0.7	1.2	-1.8	2.1	-1.8	-2.4	-2.3	-2.3	-2.1
Average weekly red wine intake	4.7	7.0	12.8	1.7	3.0	2.5	-1.5	-1.4	-2.9	-2.5	3.6	-3.2	-3.0	2.6	-2.9	-2.5	-2.2	-2.6	-3.0
Handedness (chirality/laterality): Left-handed	2.1	2.6	5.5	-1.3	-1.4	-1.6	-0.3	-0.3	2.2	1.4	-1.0	-0.4	2.0	-1.4	2.0	2.3	1.4	2.4	2.0
Mood swings	0.4	0.8	2.2	0.4	-0.3	0.2	-0.1	0.5	0.9	1.3	-0.6	-1.5	1.3	-1.2	0.5	0.6	0.7	1.2	0.9
Loneliness, isolation	0.1	0.2	0.6	0.3	0.6	0.3	-0.3	-0.8	-0.3	-0.0	0.0	-0.7	0.1	0.1	-0.6	-0.8	-0.3	-0.3	-0.1
Long-standing illness, disability or infirmity	0.9	1.4	4.6	0.4	1.0	0.5	-2.1	0.1	-1.1	-1.2	0.9	-1.0	-0.7	1.3	-0.9	-1.7	-1.5	-1.1	-1.4
Ever had bowel cancer screening	0.2	0.2	1.2	0.4	-0.3	-0.2	-1.1	0.5	-0.5	0.4	0.1	-0.6	0.3	-0.4	0.3	-0.2	0.4	0.0	0.0
Diabetes diagnosed by doctor	0.7	1.2	2.1	-0.1	-0.6	-1.3	0.3	1.3	1.5	1.4	-0.6	1.4	1.0	-1.3	1.1	1.1	1.4	0.8	1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.7	-0.5	0.6	0.0	-0.5	-0.8	-0.7	-0.1	0.3	-0.1	-0.5	0.1	-0.3	-0.6	-0.3	-0.6	-0.8
Friendships satisfaction	1.3	1.7	4.4	-0.7	-0.8	-1.2	-0.8	0.7	-0.6	2.1	-0.8	0.3	1.6	-2.1	1.5	1.1	1.9	1.2	1.5
Qualifications: nursing, teaching	2.0	3.2	9.4	3.1	1.7	2.1	-1.1	2.6	-2.0	-0.6	3.0	1.8	-1.8	0.5	-1.4	-0.8	-0.1	-1.4	-1.4
Commuting to job workplace: Walk	0.6	0.6	1.9	-1.2	-0.7	-1.3	0.7	0.2	0.5	0.4	-0.6	-0.3	0.9	-0.4	1.4	0.8	0.6	0.9	0.8
Eye problems/disorders: Cataract	0.4	0.4	1.4	-0.6	0.0	-0.9	0.2	-1.2	-0.5	0.7	-0.5	-1.1	0.6	-0.7	0.6	0.2	0.6	0.2	0.3
Mouth/teeth dental problems: Mouth ulcers	0.7	1.2	4.0	-1.6	-0.6	-0.3	0.7	-0.0	1.2	1.6	-1.2	-0.6	0.4	-1.5	1.3	1.2	2.0	0.1	0.6
Medication for cholesterol	0.7	1.1	2.9	-0.9	-1.1	-1.0	-0.2	-0.4	0.4	1.4	-1.0	-0.6	0.7	-1.4	1.6	1.6	1.7	0.6	0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	1.2	-0.7	1.0	0.4	-0.5	-0.6	-1.1	-0.3	0.2	0.1	-0.5	0.3	-0.3	-0.8	-0.5	-0.7	-0.8
Back pain experienced in last month	0.5	0.7	3.6	-0.6	0.1	-1.1	-0.6	-0.4	1.9	0.5	-0.8	-0.5	0.9	-0.4	0.9	0.6	0.0	1.0	1.1
Mineral and other dietary supplements	1.1	1.5	5.3	-0.8	-1.0	-0.7	1.2	0.7	2.3	1.3	-1.1	1.0	0.7	-1.3	1.1	1.6	1.4	0.8	1.5
Breast cancer (self-reported)	1.4	1.7	5.2	0.5	1.2	1.2	0.2	-2.3	-1.4	-0.7	1.6	-0.4	-1.4	0.7	-1.6	-1.5	-0.7	-1.8	-1.5
Asthma (self-reported)	0.4	0.9	2.1	-0.2	-0.1	0.9	-1.2	-0.6	0.1	-1.0	0.8	-1.0	-1.3	0.9	-1.0	-1.0	-0.5	-1.5	-1.2
Osteoporosis (self-reported)	0.3	0.4	1.6	1.0	0.5	0.4	-0.6	1.2	-1.2	0.3	0.7	0.4	-0.0	-0.3	-0.5	-0.4	0.3	-0.2	0.0
Osteoarthritis (self-reported)	0.8	1.0	4.5	1.3	1.7	1.0	-0.2	2.1	-0.5	0.2	0.9	0.9	-0.5	-0.1	-1.0	-0.9	-0.0	-0.9	-0.8
Medication: Aspirin	2.1	2.7	4.5	2.1	1.1	0.9	-1.1	-0.7	-1.6	-1.4	1.8	-1.9	-1.8	1.4	-2.0	-2.0	-1.3	-2.1	-2.0
Medication: Gliclazide	1.3	1.4	2.3	-1.1	-0.8	-1.3	-1.1	-0.3	1.1	1.5	-1.2	0.0	1.3	-1.5	1.4	1.4	1.3	1.4	1.1
Illnesses of father: None of the above (group 1)	2.6	3.2	5.6	-2.1	-1.9	-2.2	1.3	-0.3	1.4	2.0	-2.4	-0.1	1.5	-2.0	2.1	2.0	2.3	1.3	2.0
Smoking status: Current	3.2	5.2	12.1	-3.5	-2.0	-2.7	-0.7	0.2	3.3	2.3	-3.4	-1.0	2.1	-2.3	2.1	1.9	2.3	1.6	2.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	2.5	0.4	0.7	0.1	-1.2	-1.6	-0.9	-0.0	0.5	-1.2	0.4	-0.0	-0.1	-0.4	-0.4	0.3	0.1
Whole body water mass	1.2	6.8	11.7	2.6	2.8	2.9	0.5	-0.1	-2.0	-2.9	3.4	-0.4	-2.9	2.9	-3.1	-3.2	-2.9	-2.9	-3.0
Leg predicted mass (right)	1.2	6.3	11.4	2.4	2.7	2.5	0.6	0.3	-2.2	-2.9	3.4	-0.4	-2.6	2.8	-2.9	-3.0	-2.8	-2.7	-2.9
Arm fat mass (left)	1.2	4.8	9.7	1.3	1.6	2.3	0.1	0.9	-0.8	-2.7	1.7	0.9	-2.5	2.7	-2.6	-3.1	-2.8	-3.0	-2.8
Number of self-reported non-cancer illnesses	1.2	2.1	5.6	0.7	1.7	0.9	-0.4	-0.8	-0.8	-1.1	1.3	-1.2	-1.5	1.2	-1.7	-2.4	-1.1	-2.2	-2.1
Average weekly champagne plus white wine intake	1.7	2.4	6.7	1.9	1.5	2.2	0.5	1.4	-1.5	-0.6	2.6	1.1	-2.2	0.6	-1.7	-0.6	-0.1	-1.8	-1.7
Miserableness	0.3	0.6	3.1	0.8	0.0	-0.1	-1.8	1.6	-0.0	0.7	0.1	-1.1	0.2	-0.7	-0.1	0.1	0.8	-0.1	0.5
Guilty feelings	1.1	1.6	5.3	0.0	0.8	1.4	0.8	-0.7	-1.7	-1.7	-0.0	-1.2	-0.4	1.7	-1.4	-1.8	-2.3	-0.3	-1.0
Wears glasses or contact lenses	0.3	0.3	0.9	0.5	0.4	1.0	0.8	0.1	0.0	-0.4	0.7	-0.0	-0.7	0.5	-0.9	-0.5	-0.4	-0.7	-0.6
Ever taken oral contraceptive pill	0.3	0.3	1.3	-0.5	-0.1	0.9	1.1	-0.8	-0.1	0.0	0.2	0.7	-0.4	-0.1	-0.6	-0.3	0.4	-0.7	-0.6
Hearing aid user	0.2	0.2	1.0	0.2	-0.5	-0.4	-0.6	0.4	-0.2	-0.4	-0.5	1.0	0.6	0.3	0.1	-0.5	-0.7	0.4	0.0
Mother’s age at death	1.5	1.8	3.3	1.4	1.3	0.7	-1.3	1.4	-1.4	-1.5	0.8	1.8	-1.4	1.5	-1.4	-1.4	-1.4	-1.2	-1.4
Financial situation satisfaction	0.4	0.5	2.0	1.4	-0.1	0.0	0.9	1.2	0.4	0.6	0.0	0.9	0.5	-0.6	0.6	0.4	0.5	0.5	0.5
Tinnitus: Yes, now most or all of the time	0.4	0.5	2.0	-1.0	0.1	-0.7	-0.8	1.4	0.0	0.2	-1.3	0.9	0.7	-0.2	0.7	0.4	-0.1	0.7	0.1
Commuting to job workplace: Public transport	2.0	2.4	5.9	2.0	1.3	0.5	-0.6	0.9	-2.4	-1.4	2.2	1.4	-1.3	1.4	-1.8	-2.0	-1.6	-1.4	-1.5
Eye problems/disorders: Glaucoma	0.2	0.3	1.5	1.2	-0.0	-0.5	-0.1	-1.0	0.3	-0.2	0.7	-0.0	-0.1	0.2	-0.2	0.5	-0.4	0.5	-0.1
Medication: Blood pressure	4.0	7.6	13.4	3.1	2.6	2.5	-0.5	1.3	-2.7	-3.0	3.7	0.3	-3.0	2.9	-3.3	-3.4	-2.8	-3.1	-2.9
Pain type(s) experienced in last month: Hip pain	0.5	0.6	3.3	-0.9	-0.4	-1.1	-0.0	-1.2	1.8	0.5	0.0	-1.4	0.0	-0.4	0.4	0.5	0.6	-0.1	0.3
Supplements: Fish oil (including cod liver oil)	1.3	1.6	5.0	0.9	0.9	0.9	-0.5	-0.9	-2.2	-1.6	1.3	-1.1	-0.7	1.5	-1.1	-1.6	-1.7	-0.7	-1.5
High cholesterol (Self-reported)	0.2	0.3	1.3	0.4	-1.1	0.2	-0.3	0.0	0.5	-0.0	-0.3	0.6	-0.9	0.1	-0.5	-0.3	0.4	-1.1	-0.7
Medication: Bendroflumethiazide	5.1	7.7	15.8	2.4	2.6	2.9	-1.0	0.6	-4.0	-2.5	3.2	-0.5	-3.3	2.5	-3.5	-3.3	-2.3	-3.5	-3.2
Medication: Paracetamol	0.7	1.2	4.9	-0.3	0.4	0.8	0.4	-1.3	0.4	-1.7	-0.0	-2.2	-0.7	1.7	-1.1	-0.6	-1.6	-0.4	-0.6
Medication: Lisinopril	0.8	1.0	3.2	1.0	1.1	0.7	-0.0	1.6	-1.3	-0.5	1.8	1.2	-0.6	0.5	-0.8	-1.3	-0.7	-0.9	-0.8
Medication: Atorvastatin	2.8	3.4	5.6	0.9	1.9	2.1	-0.4	-0.8	-0.4	-2.3	1.9	0.3	-2.3	2.4	-2.3	-2.3	-2.1	-2.2	-2.4
Illnesses of father: High blood pressure	1.3	1.6	5.0	1.6	0.8	1.2	-0.4	0.5	-1.6	-0.9	2.2	0.8	-1.2	0.9	-1.3	-1.6	-0.8	-1.6	-1.4
Alcohol drinker status: Never	0.6	0.7	2.4	-1.6	-0.4	-0.5	-0.5	1.1	-1.1	0.4	-0.9	1.2	1.1	-0.4	0.6	0.0	-0.1	1.0	0.9
Ever smoked	0.9	1.7	7.1	-2.7	-0.8	-1.2	-1.3	-0.1	2.2	1.2	-2.0	-0.6	0.7	-1.2	1.1	0.7	1.0	0.4	0.6
Basal metabolic rate	1.3	7.3	11.7	2.5	2.8	2.9	0.4	0.2	-1.9	-3.1	3.3	-0.2	-3.0	3.1	-3.2	-3.4	-3.1	-3.1	-3.2
Leg fat percentage (left)	0.4	1.6	4.1	0.5	0.3	0.9	-0.2	0.8	0.4	-1.5	0.2	1.2	-1.4	1.5	-1.5	-2.0	-1.6	-2.0	-1.6
Arm fat-free mass (left)	1.2	6.3	10.8	2.8	2.6	2.5	0.2	-0.1	-1.8	-2.8	3.3	-0.1	-2.7	2.7	-3.1	-3.2	-2.9	-2.8	-2.8
Number of operations (self-reported)	2.4	3.6	7.1	0.7	2.3	1.6	-0.9	-1.2	-1.9	-1.4	2.0	-2.1	-2.0	1.4	-2.1	-2.5	-1.6	-2.5	-2.7
Average weekly beer plus cider intake	2.4	3.5	6.1	-2.5	-2.1	-1.8	-0.1	-1.6	2.5	1.4	-2.3	-2.0	2.1	-1.4	2.1	1.5	1.2	1.9	2.1
Irritability	2.6	4.3	13.3	-0.7	-2.4	-1.7	1.4	0.1	3.6	2.0	-1.6	-0.5	2.5	-2.0	2.0	2.5	1.9	2.6	2.6
Risk taking	2.7	3.9	6.9	-2.5	-2.0	-1.6	-0.2	1.4	2.3	2.0	-2.6	1.2	2.4	-1.9	2.3	2.0	1.6	2.2	2.1
Ever had prostate specific antigen (PSA) test	1.6	1.9	4.2	1.7	2.1	0.8	-0.6	-0.2	-2.0	-1.0	1.7	-0.8	-0.9	1.1	-1.3	-1.8	-1.4	-1.2	-1.6
Fractured/broken bones in last 5 years	1.1	1.5	4.3	2.1	1.5	0.3	0.3	1.5	-1.7	-0.8	1.6	-0.3	-1.2	0.8	-1.0	-1.1	-0.7	-1.3	-1.3
Age started oral contraceptive pill	0.3	0.4	2.5	0.7	0.1	0.2	0.6	-1.6	-0.2	-0.3	0.9	-1.1	0.0	0.3	-0.4	-0.2	-0.4	0.2	-0.3
Diastolic blood pressure, automated reading	7.7	23.8	40.3	3.9	4.3	4.4	-2.0	-0.3	-5.8	-5.7	5.9	0.3	-5.2	5.7	-5.5	-6.3	-5.8	-5.5	-5.3
Ever depressed for a whole week	1.4	1.8	3.2	-0.4	-1.4	-1.0	-0.0	0.4	1.2	1.5	-1.5	1.2	1.6	-1.4	1.3	1.8	1.4	1.8	1.7
Unable to work because of sickness or disability	7.2	9.3	14.5	-3.8	-3.6	-2.8	0.8	-2.2	3.8	3.2	-3.4	-1.4	2.7	-3.2	3.6	3.6	3.2	2.5	3.1
Commuting to job workplace: Cycle	0.3	0.3	1.2	0.1	0.6	-0.4	-0.2	-0.4	-1.1	0.3	-0.1	-1.0	0.8	-0.4	0.8	0.1	0.3	0.5	0.8
Myopia	1.6	2.4	5.6	1.8	1.4	1.2	-0.9	0.1	-2.4	-1.8	1.8	-0.3	-2.0	1.8	-1.5	-1.2	-1.3	-1.6	-1.9
Vascular/heart problems diagnosed by doctor	5.5	15.1	24.8	-3.1	-3.7	-3.7	-0.4	0.7	3.5	4.7	-4.0	0.1	4.7	-4.7	4.8	4.7	4.4	4.6	5.0
Cholesterol lowering medication	0.2	0.2	1.0	-0.7	-1.0	0.3	-0.5	0.1	1.0	-0.1	-0.9	-0.2	0.0	0.2	-0.2	-0.3	-0.2	0.1	0.2
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	2.1	-0.5	-0.4	-1.4	0.1	-0.8	0.0	-0.0	-0.7	-0.8	0.2	0.0	0.1	0.0	-0.2	0.1	0.0
Pain experienced in last month	0.9	1.5	6.1	0.1	1.0	1.8	-0.3	0.1	-2.5	-1.2	1.1	0.4	-1.5	1.2	-1.0	-1.1	-0.9	-1.4	-1.3
Supplements: Calcium	0.9	1.0	3.0	0.5	1.1	0.9	0.5	0.7	-1.7	-0.8	1.4	0.0	-1.0	0.8	-0.9	-1.2	-0.9	-1.2	-1.1
Basal cell carcinoma (self-reported)	1.3	1.5	3.2	1.4	1.1	1.0	0.2	0.3	-1.4	-1.4	1.8	-0.7	-1.0	1.4	-1.4	-1.5	-1.6	-1.0	-1.4
Heart attack/myocardial infarction (self-reported)	1.8	2.3	5.1	0.9	1.5	1.5	0.8	0.1	-1.6	-1.8	0.6	0.4	-2.0	1.8	-1.9	-1.6	-1.7	-1.9	-2.2
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	2.8	-0.1	-0.5	-0.6	-1.7	0.7	0.4	0.5	-0.7	-0.9	0.3	-0.4	0.5	0.3	0.3	0.3	0.3
Heart disease (siblings)	1.6	2.0	4.2	-0.0	0.8	1.8	-0.2	-1.3	-2.0	-1.6	1.5	-1.2	-0.7	1.6	-1.5	-2.1	-2.0	-0.9	-1.3
Alcohol drinker status: Previous	1.9	2.2	6.3	-0.9	-1.5	-1.5	0.9	-1.3	2.5	1.6	-1.4	-1.2	1.2	-1.6	1.5	1.8	1.6	1.2	1.6
Pack years of smoking	1.9	2.8	10.8	-1.5	-1.1	-2.0	0.8	0.1	3.3	1.7	-2.3	0.6	1.6	-1.7	1.3	1.6	1.6	1.4	1.6
Impedance of whole body	0.1	0.4	4.5	-2.1	-0.6	0.6	-0.1	-0.8	-0.4	-0.3	-0.4	0.2	-0.2	0.3	0.3	0.1	-0.1	-0.0	-0.1
Leg fat mass (left)	0.9	3.5	7.4	0.9	1.2	1.9	0.3	0.7	-0.2	-2.4	1.1	0.9	-2.2	2.4	-2.3	-2.7	-2.5	-2.6	-2.4
Arm predicted mass (left)	1.3	6.7	11.8	2.7	2.7	2.8	0.4	-0.1	-1.8	-2.8	3.4	0.1	-2.8	2.8	-3.2	-3.3	-2.9	-2.9	-2.9