Best TWAS P=8.63e-09 · Best GWAS P=3.45e-07 conditioned to 0.137
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | DCAF16 | 0.10 | 0.01 | enet | 6 | 0.02 | 4.7e-02 | -4.7 | 5.7 | 1.1e-08 | -0.84 | 0.04 | 0.82 | FALSE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | DCAF16 | 0.09 | 0.02 | lasso | 3 | 0.04 | 5.2e-05 | 4.3 | 5.8 | 8.6e-09 | -0.70 | 0.06 | 0.82 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DCAF16 | 0.04 | 0.04 | blup | 31 | 0.04 | 2.2e-05 | 3.9 | 5.1 | 2.8e-07 | -0.63 | 0.12 | 0.56 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | DCAF16 | 0.07 | 0.04 | blup | 31 | 0.07 | 4.9e-07 | 4.4 | 5.5 | 3.6e-08 | -0.74 | 0.11 | 0.80 | FALSE |