Best TWAS P=1.25e-07 · Best GWAS P=3.59e-06 conditioned to 0.875
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Nucleus accumbens basal ganglia | PFDN1 | 0.16 | 0.01 | lasso | 5 | 0.03 | 5.6e-02 | 4.1 | 5.3 | 1.2e-07 | -0.86 | 0.02 | 0.59 | TRUE |
| 2 | GTEx | Esophagus Gastroesophageal Junction | PFDN1 | 0.24 | 0.09 | enet | 20 | 0.12 | 3.3e-05 | -4.6 | 5.1 | 3.1e-07 | -0.87 | 0.02 | 0.92 | FALSE |