Best TWAS P=3.36e-09 · Best GWAS P=4.97e-10 conditioned to 2.84e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | FOXO6 | 0.27 | 0.16 | lasso | 6 | 0.32 | 1.0e-24 | -3.7 | -5.9 | 3.4e-09 | 0.40 | 0.98 | 0.02 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | FOXO6 | 0.07 | 0.03 | enet | 14 | 0.05 | 1.5e-06 | -4.2 | -5.4 | 6.7e-08 | 0.35 | 0.85 | 0.10 | FALSE |