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chr3:182,655,858-184,099,956

Best TWAS P=1.34e-09 · Best GWAS P=1.58e-08 conditioned to 0.919

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	KLHL24	0.42	0.60	bslmm	493	0.66	4.5e-107	-5.5	-5.3	1.4e-07	0.92	0.02	0.98	FALSE
2	GTEx	Adipose Subcutaneous	KLHL24	0.15	0.10	lasso	6	0.10	1.4e-08	-5.5	5.5	3.9e-08	-0.98	0.02	0.98	FALSE
3	GTEx	Brain Caudate basal ganglia	KLHL24	0.22	0.21	lasso	3	0.19	3.5e-06	-5.6	5.6	2.3e-08	-0.98	0.02	0.96	FALSE
4	GTEx	Brain Cerebellum	KLHL24	0.52	0.14	enet	26	0.16	1.9e-05	-5.6	5.4	7.2e-08	-0.88	0.02	0.97	FALSE
5	GTEx	Brain Cortex	KLHL24	0.21	0.15	lasso	3	0.07	6.1e-03	-5.5	5.4	5.4e-08	-0.98	0.02	0.93	FALSE
6	GTEx	Brain Frontal Cortex BA9	KLHL24	0.36	0.23	lasso	6	0.15	9.3e-05	-5.5	5.2	1.8e-07	-0.93	0.02	0.96	FALSE
7	GTEx	Breast Mammary Tissue	KLHL24	0.25	0.13	lasso	5	0.11	3.4e-06	-5.6	5.5	3.3e-08	-0.97	0.02	0.98	FALSE
8	GTEx	Esophagus Muscularis	KLHL24	0.10	0.12	lasso	1	0.09	4.4e-06	-5.6	5.6	2.2e-08	-0.99	0.02	0.98	FALSE
9	GTEx	Nerve Tibial	KLHL24	0.08	0.06	lasso	3	0.05	1.5e-04	-5.5	5.5	3.3e-08	-0.97	0.03	0.96	FALSE
10	GTEx	Skin Sun Exposed Lower leg	KLHL24	0.09	0.06	lasso	10	0.05	9.5e-05	-5.5	5.5	3.7e-08	-0.98	0.02	0.97	FALSE
11	GTEx	Testis	KLHL24	0.17	0.10	lasso	4	0.10	4.0e-05	-5.6	5.6	2.2e-08	-0.99	0.02	0.98	FALSE
12	YFS	Blood	KLHL24	0.02	0.01	lasso	2	0.01	1.4e-03	-5.1	5.4	7.4e-08	-0.89	0.03	0.97	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	KLHL24	0.05	0.05	blup	53	0.05	1.1e-06	-5.5	5.9	4.6e-09	-0.94	0.02	0.98	FALSE
14	The Cancer Genome Atlas	Prostate Adenocarcinoma	KLHL24	0.03	0.04	enet	5	0.04	5.1e-05	-5.7	5.7	9.6e-09	-0.98	0.02	0.97	FALSE
15	The Cancer Genome Atlas	Testicular Germ Cell Tumors	KLHL24	0.16	0.16	blup	53	0.21	4.3e-08	-5.6	6.1	1.3e-09	-0.94	0.02	0.98	TRUE
16	The Cancer Genome Atlas	Thyroid Carcinoma	KLHL24	0.10	0.09	blup	53	0.09	1.7e-09	-5.6	5.7	1.1e-08	-0.92	0.02	0.98	FALSE