TWAS
hub
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Usage
Models
Genes
Traits
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Traits
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Birth weight
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chr7:72,674,074-73,803,303
Best TWAS P=8.61e-10 · Best GWAS P=2.65e-09 conditioned to 0.0306
72.8M
73M
73.2M
73.4M
73.6M
73.8M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
BCL7B
0.02
0.01
blup
5
0.02
2.7e-03
4.3
-6.1
8.6e-10
-0.73
0.00
0.62
TRUE
5
The Cancer Genome Atlas
Liver Hepatocellular Carcinoma
BCL7B
0.08
0.04
blup
5
0.06
1.0e-03
4.3
-6.1
1.0e-09
-0.80
0.00
0.88
FALSE
2
GTEx
Artery Tibial
BCL7B
0.18
0.07
lasso
3
0.06
1.4e-05
5.9
-6.0
2.5e-09
-0.90
0.00
0.98
FALSE
1
GTEx
Adipose Subcutaneous
BCL7B
0.16
0.14
lasso
3
0.13
1.0e-10
5.9
-5.7
1.6e-08
-0.90
0.00
1.00
FALSE
3
NTR
Blood
WBSCR22
0.03
0.01
bslmm
270
0.01
1.2e-05
2.8
5.1
2.9e-07
0.69
0.02
0.98
FALSE