Best TWAS P=8.61e-10 · Best GWAS P=2.65e-09 conditioned to 0.0306
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | BCL7B | 0.16 | 0.14 | lasso | 3 | 0.13 | 1.0e-10 | 5.9 | -5.7 | 1.6e-08 | -0.90 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Artery Tibial | BCL7B | 0.18 | 0.07 | lasso | 3 | 0.06 | 1.4e-05 | 5.9 | -6.0 | 2.5e-09 | -0.90 | 0.00 | 0.98 | FALSE |
| 3 | NTR | Blood | WBSCR22 | 0.03 | 0.01 | bslmm | 270 | 0.01 | 1.2e-05 | 2.8 | 5.1 | 2.9e-07 | 0.69 | 0.02 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | BCL7B | 0.02 | 0.01 | blup | 5 | 0.02 | 2.7e-03 | 4.3 | -6.1 | 8.6e-10 | -0.73 | 0.00 | 0.62 | TRUE |
| 5 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | BCL7B | 0.08 | 0.04 | blup | 5 | 0.06 | 1.0e-03 | 4.3 | -6.1 | 1.0e-09 | -0.80 | 0.00 | 0.88 | FALSE |