Best TWAS P=2.51e-13 · Best GWAS P=8.29e-17 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Liver | PTCH1 | 0.25 | 0.06 | enet | 11 | 0.03 | 4.9e-02 | 8.3 | 6.5 | 1.1e-10 | 0.91 | 0.01 | 0.94 | FALSE |
2 | YFS | Blood | PTCH1 | 0.09 | 0.05 | lasso | 8 | 0.05 | 1.2e-15 | 7.1 | 7.3 | 2.5e-13 | 0.95 | 0.05 | 0.95 | TRUE |