Best TWAS P=5.08e-10 · Best GWAS P=5.46e-12 conditioned to 0.00288
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | ITPR2 | 0.2 | 0.15 | enet | 41 | 0.18 | 2.2e-21 | -6.6 | -6.0 | 1.7e-09 | -0.81 | 0.02 | 0.98 | FALSE |
2 | ROSMAP | Brain Pre-frontal Cortex | ITPR2 | 0.1 | 0.06 | enet | 9 | 0.06 | 1.1e-07 | 6.3 | -6.2 | 5.1e-10 | -0.92 | 0.01 | 0.99 | TRUE |