Best TWAS P=1.86e-07 · Best GWAS P=1.73e-07 conditioned to 0.0957
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | SRR | 0.44 | 0.28 | lasso | 8 | 0.26 | 2.5e-09 | -4.8 | 5.2 | 2.3e-07 | -0.85 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Brain Caudate basal ganglia | SRR | 0.26 | 0.03 | lasso | 3 | 0.02 | 8.6e-02 | -5.2 | 5.1 | 2.9e-07 | -0.92 | 0.01 | 0.91 | FALSE |
| 3 | GTEx | Breast Mammary Tissue | SRR | 0.20 | 0.21 | lasso | 3 | 0.20 | 8.2e-11 | -4.9 | 5.2 | 1.9e-07 | -0.82 | 0.01 | 0.99 | TRUE |