[Hub]/) : Traits : Birth weight : ← →

chr17:6,397,773-8,057,572

Best TWAS P=2.87e-31 · Best GWAS P=2.83e-27 conditioned to 0.364

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
106	The Cancer Genome Atlas	Testicular Germ Cell Tumors	C17orf81	0.13	0.09	blup	43	0.08	1.1e-03	-10.71	-11.6	2.9e-31	0.90	0.01	0.94	TRUE
110	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	C17orf81	0.19	0.06	blup	42	0.10	1.2e-03	-10.71	-11.6	4.4e-31	0.86	0.01	0.92	FALSE
101	The Cancer Genome Atlas	Soft Tissue Sarcoma	C17orf81	0.11	0.10	blup	47	0.14	2.1e-08	-10.63	-11.4	2.7e-30	0.90	0.02	0.98	FALSE
44	GTEx	Prostate	ELP5	0.65	0.43	lasso	10	0.44	1.6e-12	-10.69	-11.4	3.3e-30	0.85	0.02	0.98	FALSE
86	The Cancer Genome Atlas	Brain Lower Grade Glioma	ACADVL	0.03	0.03	blup	37	0.04	5.5e-05	-8.37	-11.3	9.0e-30	0.94	0.02	0.98	FALSE
90	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C17orf81	0.10	0.07	blup	44	0.11	8.1e-06	-10.71	-11.3	1.0e-29	0.87	0.02	0.98	FALSE
74	The Cancer Genome Atlas	Breast Invasive Carcinoma	DULLARD	0.03	0.07	enet	13	0.07	5.8e-15	-10.29	11.2	3.6e-29	-0.91	0.02	0.98	FALSE
88	The Cancer Genome Atlas	Brain Lower Grade Glioma	DULLARD	0.07	0.07	enet	12	0.10	2.0e-11	-10.49	11.1	8.0e-29	-0.86	0.02	0.98	FALSE
37	GTEx	Muscle Skeletal	DLG4	0.12	0.05	lasso	4	0.05	2.3e-05	-10.78	11.1	9.3e-29	-0.95	0.00	0.99	FALSE
13	GTEx	Artery Tibial	ACADVL	0.12	0.10	enet	3	0.10	2.7e-08	-10.70	-11.1	1.3e-28	0.93	0.01	0.99	FALSE
104	The Cancer Genome Atlas	Stomach Adenocarcinoma	C17orf81	0.03	0.02	blup	47	0.02	1.3e-02	-10.71	-11.1	1.7e-28	0.92	0.02	0.96	FALSE
9	GTEx	Artery Aorta	ACADVL	0.10	0.09	lasso	3	0.10	2.4e-06	-10.78	-11.0	2.6e-28	0.99	0.01	0.99	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ACADVL	0.09	0.06	bslmm	467	0.07	2.1e-08	-10.68	-11.0	2.9e-28	0.91	0.01	0.99	FALSE
52	GTEx	Testis	ELP5	0.48	0.42	enet	10	0.42	3.3e-20	-10.69	-11.0	3.0e-28	0.89	0.01	0.99	FALSE
96	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	DULLARD	0.10	0.10	enet	8	0.10	7.7e-05	-10.78	11.0	3.6e-28	-0.95	0.01	0.98	FALSE
83	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DULLARD	0.07	0.10	blup	42	0.12	1.1e-13	-10.63	11.0	4.0e-28	-0.92	0.03	0.97	FALSE
47	GTEx	Skin Sun Exposed Lower leg	ELP5	0.49	0.51	enet	34	0.54	3.1e-52	-10.71	-10.9	1.1e-27	0.87	0.01	0.99	FALSE
32	GTEx	Esophagus Muscularis	ELP5	0.52	0.52	lasso	4	0.53	6.4e-37	-10.69	-10.9	1.2e-27	0.88	0.01	0.99	FALSE
33	GTEx	Heart Atrial Appendage	ELP5	0.42	0.44	lasso	3	0.44	6.3e-22	-10.69	-10.9	1.5e-27	0.87	0.02	0.98	FALSE
3	GTEx	Adipose Subcutaneous	ELP5	0.35	0.38	enet	13	0.40	1.7e-34	-10.69	-10.9	1.6e-27	0.88	0.01	0.99	FALSE
38	GTEx	Muscle Skeletal	ELP5	0.46	0.59	lasso	9	0.60	1.9e-73	-10.69	-10.9	1.8e-27	0.89	0.01	0.99	FALSE
99	The Cancer Genome Atlas	Prostate Adenocarcinoma	DULLARD	0.05	0.08	blup	42	0.07	1.7e-07	-10.23	10.9	1.9e-27	-0.90	0.05	0.95	FALSE
76	The Cancer Genome Atlas	Colon Adenocarcinoma	C17orf81	0.14	0.14	lasso	7	0.15	3.3e-09	-10.28	-10.8	2.3e-27	0.83	0.02	0.98	FALSE
92	The Cancer Genome Atlas	Lung Adenocarcinoma	DULLARD	0.04	0.06	blup	42	0.08	3.3e-09	-9.85	10.8	2.3e-27	-0.91	0.02	0.98	FALSE
22	GTEx	Cells EBV-transformed lymphocytes	ELP5	0.40	0.28	lasso	10	0.23	3.5e-08	-10.71	-10.8	2.9e-27	0.89	0.02	0.98	FALSE
69	ROSMAP	Brain Pre-frontal Cortex	CLDN7	0.07	0.06	lasso	4	0.05	3.9e-07	-10.82	-10.8	2.9e-27	1.00	0.00	0.99	FALSE
20	GTEx	Breast Mammary Tissue	ELP5	0.45	0.51	lasso	8	0.48	7.1e-28	-10.71	-10.8	3.2e-27	0.89	0.01	0.99	FALSE
51	GTEx	Stomach	ELP5	0.49	0.54	lasso	7	0.52	7.6e-29	-10.69	-10.8	3.2e-27	0.88	0.01	0.99	FALSE
93	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C17orf81	0.06	0.12	lasso	8	0.12	6.3e-14	-10.78	-10.8	3.2e-27	0.98	0.01	0.99	FALSE
40	GTEx	Nerve Tibial	ELP5	0.44	0.50	lasso	8	0.50	4.3e-40	-10.69	-10.8	3.5e-27	0.87	0.01	0.99	FALSE
43	GTEx	Pituitary	ELP5	0.45	0.44	lasso	4	0.40	5.3e-11	-10.60	-10.8	3.5e-27	0.82	0.03	0.97	FALSE
46	GTEx	Skin Sun Exposed Lower leg	DVL2	0.10	0.03	lasso	2	0.02	1.5e-02	-10.78	-10.8	3.7e-27	0.99	0.01	0.99	FALSE
27	GTEx	Colon Transverse	ELP5	0.58	0.59	lasso	4	0.56	4.7e-32	-10.69	-10.8	4.0e-27	0.87	0.01	0.99	FALSE
39	GTEx	Muscle Skeletal	CLDN7	0.13	0.08	lasso	7	0.09	9.8e-09	-10.32	-10.8	4.6e-27	0.92	0.03	0.97	FALSE
28	GTEx	Esophagus Gastroesophageal Junction	ELP5	0.68	0.61	lasso	5	0.58	1.6e-25	-10.69	-10.8	5.1e-27	0.86	0.01	0.99	FALSE
34	GTEx	Heart Left Ventricle	ELP5	0.41	0.48	lasso	3	0.46	4.0e-27	-10.69	-10.8	5.1e-27	0.87	0.01	0.99	FALSE
23	GTEx	Cells Transformed fibroblasts	ELP5	0.48	0.55	lasso	7	0.58	2.9e-53	-10.71	-10.8	5.2e-27	0.88	0.01	0.99	FALSE
53	GTEx	Thyroid	ELP5	0.46	0.56	lasso	9	0.56	1.6e-50	-10.71	-10.8	5.7e-27	0.89	0.01	0.99	FALSE
5	GTEx	Adipose Visceral Omentum	ELP5	0.49	0.56	lasso	6	0.55	1.3e-33	-10.71	-10.7	6.9e-27	0.88	0.01	0.99	FALSE
79	The Cancer Genome Atlas	Glioblastoma Multiforme	DULLARD	0.11	0.15	enet	11	0.15	2.5e-05	-10.50	10.7	7.3e-27	-0.87	0.03	0.95	FALSE
29	GTEx	Esophagus Mucosa	ELP5	0.59	0.67	lasso	7	0.66	2.7e-58	-10.71	-10.7	8.5e-27	0.88	0.01	0.99	FALSE
85	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	DULLARD	0.13	0.11	blup	42	0.13	8.7e-08	-10.23	10.7	9.3e-27	-0.90	0.05	0.95	FALSE
35	GTEx	Liver	ELP5	0.38	0.34	lasso	4	0.32	1.2e-09	-10.71	-10.7	9.6e-27	0.88	0.01	0.99	FALSE
81	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DULLARD	0.03	0.03	blup	42	0.03	9.3e-05	-10.82	10.7	9.9e-27	-0.93	0.01	0.99	FALSE
41	GTEx	Pancreas	ELP5	0.38	0.37	lasso	6	0.36	2.7e-16	-10.71	-10.7	1.1e-26	0.90	0.02	0.98	FALSE
54	GTEx	Thyroid	CLDN7	0.08	0.08	lasso	1	0.06	1.2e-05	-10.69	10.7	1.2e-26	-0.86	0.02	0.98	FALSE
60	METSIM	Adipose	ELP5	0.24	0.28	lasso	11	0.28	1.4e-42	-10.71	-10.7	1.4e-26	0.88	0.01	0.99	FALSE
71	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C17orf81	0.10	0.17	lasso	7	0.17	3.4e-14	-10.71	-10.7	1.6e-26	0.92	0.02	0.98	FALSE
107	The Cancer Genome Atlas	Thyroid Carcinoma	C17orf81	0.19	0.23	lasso	5	0.24	1.4e-23	-10.71	-10.7	1.7e-26	0.83	0.01	0.99	FALSE
48	GTEx	Skin Sun Exposed Lower leg	CTDNEP1	0.10	0.06	lasso	6	0.06	9.5e-06	-10.32	10.6	1.9e-26	-0.91	0.01	0.98	FALSE
57	GTEx	Whole Blood	ELP5	0.23	0.16	enet	13	0.18	4.8e-16	-10.49	-10.6	2.1e-26	0.89	0.03	0.97	FALSE
105	The Cancer Genome Atlas	Stomach Adenocarcinoma	DULLARD	0.03	0.04	lasso	1	0.03	1.8e-03	-10.63	10.6	2.1e-26	-0.89	0.03	0.88	FALSE
25	GTEx	Colon Sigmoid	ELP5	0.55	0.55	lasso	7	0.51	7.0e-21	-10.69	-10.6	3.0e-26	0.87	0.02	0.98	FALSE
7	GTEx	Adrenal Gland	ELP5	0.52	0.44	lasso	7	0.43	9.0e-17	-10.69	-10.6	3.2e-26	0.87	0.01	0.99	FALSE
10	GTEx	Artery Aorta	ELP5	0.51	0.56	lasso	3	0.57	1.8e-37	-10.28	-10.6	3.6e-26	0.86	0.02	0.98	FALSE
97	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	DULLARD	0.07	0.02	blup	42	0.06	2.3e-03	7.83	10.6	3.6e-26	-0.92	0.03	0.75	FALSE
45	GTEx	Skin Not Sun Exposed Suprapubic	ELP5	0.51	0.55	enet	22	0.55	6.1e-36	-10.69	-10.6	4.0e-26	0.89	0.01	0.99	FALSE
56	GTEx	Whole Blood	ACADVL	0.07	0.04	lasso	2	0.03	3.4e-04	-10.68	-10.6	4.9e-26	0.90	0.01	0.98	FALSE
59	METSIM	Adipose	CTDNEP1	0.12	0.11	lasso	5	0.11	2.3e-16	-10.32	10.5	5.2e-26	-0.90	0.06	0.94	FALSE
16	GTEx	Brain Frontal Cortex BA9	ELP5	0.31	0.20	lasso	7	0.19	9.3e-06	-10.71	-10.5	5.7e-26	0.81	0.02	0.94	FALSE
12	GTEx	Artery Coronary	ELP5	0.64	0.55	lasso	9	0.55	7.2e-22	-10.69	-10.5	5.8e-26	0.87	0.01	0.99	FALSE
21	GTEx	Breast Mammary Tissue (Male)	ELP5	0.38	0.43	lasso	6	0.42	6.4e-11	-10.28	-10.5	5.9e-26	0.87	0.02	0.98	FALSE
98	The Cancer Genome Atlas	Prostate Adenocarcinoma	C17orf81	0.11	0.21	lasso	8	0.21	4.5e-22	-10.28	-10.5	6.9e-26	0.88	0.03	0.97	FALSE
95	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C17orf81	0.17	0.15	lasso	5	0.16	5.0e-07	-10.28	-10.5	7.3e-26	0.85	0.02	0.98	FALSE
30	GTEx	Esophagus Mucosa	CTDNEP1	0.21	0.17	lasso	6	0.17	2.3e-11	-10.29	10.5	7.8e-26	-0.94	0.02	0.98	FALSE
31	GTEx	Esophagus Mucosa	CLDN7	0.14	0.04	lasso	5	0.02	8.8e-03	-10.50	10.5	8.7e-26	-0.82	0.04	0.93	FALSE
108	The Cancer Genome Atlas	Thyroid Carcinoma	CLDN7	0.05	0.06	blup	47	0.05	5.2e-06	-10.28	10.5	9.6e-26	-0.82	0.02	0.98	FALSE
100	The Cancer Genome Atlas	Rectum Adenocarcinoma	DULLARD	0.15	0.10	blup	41	0.11	1.4e-03	-10.29	10.5	1.4e-25	-0.91	0.02	0.77	FALSE
4	GTEx	Adipose Subcutaneous	CTDNEP1	0.12	0.08	lasso	2	0.09	1.7e-07	-10.29	10.4	1.5e-25	-0.91	0.06	0.94	FALSE
72	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	DULLARD	0.04	0.07	lasso	2	0.05	3.3e-05	-10.29	10.4	1.9e-25	-0.91	0.03	0.96	FALSE
14	GTEx	Artery Tibial	ELP5	0.49	0.55	lasso	6	0.57	2.6e-54	-10.71	-10.4	2.6e-25	0.88	0.01	0.99	FALSE
65	ROSMAP	Brain Pre-frontal Cortex	DLG4	0.07	0.09	lasso	1	0.08	3.8e-10	-10.40	10.4	2.6e-25	-0.77	0.20	0.80	FALSE
36	GTEx	Lung	ELP5	0.35	0.43	enet	18	0.44	2.7e-36	-10.69	-10.4	2.7e-25	0.88	0.01	0.99	FALSE
15	GTEx	Brain Caudate basal ganglia	ELP5	0.64	0.57	enet	13	0.59	1.1e-20	-10.71	-10.4	2.9e-25	0.89	0.01	0.99	FALSE
50	GTEx	Spleen	CLDN7	0.51	0.26	lasso	10	0.26	2.6e-07	-10.32	-10.4	3.1e-25	0.89	0.04	0.96	FALSE
49	GTEx	Spleen	ELP5	0.67	0.47	lasso	6	0.46	2.2e-13	-10.69	-10.4	3.8e-25	0.89	0.02	0.98	FALSE
8	GTEx	Adrenal Gland	CLDN7	0.30	0.10	lasso	5	0.12	5.6e-05	-10.29	10.3	4.4e-25	-0.89	0.04	0.93	FALSE
19	GTEx	Brain Putamen basal ganglia	ELP5	0.67	0.38	lasso	11	0.39	2.6e-10	-10.71	-10.3	5.7e-25	0.87	0.02	0.98	FALSE
75	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	C17orf81	0.12	0.14	blup	43	0.14	1.7e-07	-10.63	-10.3	6.0e-25	0.81	0.03	0.97	FALSE
66	ROSMAP	Brain Pre-frontal Cortex	ELP5	0.44	0.52	enet	35	0.55	2.1e-84	-10.49	-10.3	7.0e-25	0.90	0.03	0.97	FALSE
67	ROSMAP	Brain Pre-frontal Cortex	CTDNEP1	0.23	0.30	bslmm	447	0.31	5.7e-40	-10.32	10.3	1.2e-24	-0.89	0.07	0.93	FALSE
94	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	DULLARD	0.03	0.03	enet	8	0.04	1.2e-05	-10.63	10.2	1.3e-24	-0.89	0.04	0.96	FALSE
18	GTEx	Brain Nucleus accumbens basal ganglia	ELP5	0.44	0.39	lasso	7	0.38	5.2e-11	-10.71	-10.2	1.7e-24	0.88	0.01	0.99	FALSE
91	The Cancer Genome Atlas	Lung Adenocarcinoma	C17orf81	0.05	0.06	blup	43	0.06	6.4e-08	-10.71	-10.2	2.1e-24	0.87	0.02	0.98	FALSE
80	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C17orf81	0.05	0.12	lasso	5	0.11	1.8e-12	-10.32	-10.2	2.3e-24	0.91	0.02	0.98	FALSE
109	The Cancer Genome Atlas	Thyroid Carcinoma	DULLARD	0.10	0.18	lasso	7	0.19	2.6e-18	-9.78	10.0	9.3e-24	-0.91	0.08	0.92	FALSE
84	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C17orf81	0.11	0.13	blup	43	0.13	8.7e-08	-10.29	-10.0	1.4e-23	0.87	0.03	0.97	FALSE
42	GTEx	Pancreas	CLDN7	0.17	0.06	lasso	3	0.02	7.4e-02	-10.69	10.0	2.0e-23	-0.85	0.02	0.86	FALSE
58	METSIM	Adipose	CLDN7	0.13	0.05	bslmm	458	0.07	2.0e-10	-10.71	-9.9	2.8e-23	0.67	0.02	0.98	FALSE
73	The Cancer Genome Atlas	Breast Invasive Carcinoma	C17orf81	0.04	0.05	blup	43	0.06	4.0e-12	-10.71	-9.9	3.2e-23	0.84	0.02	0.98	FALSE
24	GTEx	Cells Transformed fibroblasts	CTDNEP1	0.11	0.07	lasso	4	0.10	1.1e-07	-10.29	9.9	3.6e-23	-0.89	0.06	0.94	FALSE
102	The Cancer Genome Atlas	Skin Cutaneous Melanoma	C17orf81	0.35	0.24	enet	12	0.25	2.1e-07	-9.51	-9.9	5.0e-23	0.80	0.05	0.94	FALSE
89	The Cancer Genome Atlas	Brain Lower Grade Glioma	SLC2A4	0.09	0.04	lasso	4	0.06	7.2e-08	-10.82	9.9	5.1e-23	-0.87	0.00	1.00	FALSE
103	The Cancer Genome Atlas	Skin Cutaneous Melanoma	DLG4	0.12	0.10	lasso	1	0.08	3.1e-03	-9.85	-9.8	6.8e-23	0.86	0.01	0.46	FALSE
11	GTEx	Artery Aorta	CTDNEP1	0.16	0.09	lasso	3	0.06	2.4e-04	-9.85	9.8	1.2e-22	-0.85	0.06	0.91	FALSE
17	GTEx	Brain Hippocampus	ELP5	0.52	0.22	lasso	6	0.23	3.4e-06	-10.28	-9.7	2.1e-22	0.76	0.02	0.95	FALSE
68	ROSMAP	Brain Pre-frontal Cortex	SLC2A4	0.08	0.08	enet	9	0.08	5.5e-11	-8.37	9.6	5.9e-22	-0.94	0.01	0.99	FALSE
55	GTEx	Uterus	ELP5	0.52	0.51	lasso	1	0.48	3.0e-11	-9.37	-9.4	7.6e-21	0.75	0.06	0.94	FALSE
6	GTEx	Adipose Visceral Omentum	CLDN7	0.25	0.14	enet	21	0.12	7.3e-07	-10.32	-8.9	3.5e-19	0.83	0.02	0.98	FALSE
64	NTR	Blood	C17orf81	0.05	0.03	bslmm	454	0.03	6.3e-10	-10.70	8.7	4.4e-18	-0.77	0.02	0.98	FALSE
61	METSIM	Adipose	GABARAP	0.04	0.01	lasso	7	0.02	9.5e-04	5.00	8.5	2.5e-17	-0.58	0.03	0.80	FALSE
82	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C17orf81	0.08	0.05	enet	10	0.04	1.3e-05	-10.32	-8.2	2.8e-16	0.74	0.03	0.96	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SLC2A4	0.08	0.06	lasso	2	0.08	1.2e-09	-9.78	8.1	5.9e-16	-0.72	0.06	0.94	FALSE
87	The Cancer Genome Atlas	Brain Lower Grade Glioma	C17orf81	0.04	0.05	enet	8	0.04	1.2e-05	-8.37	-7.5	8.3e-14	0.76	0.08	0.89	FALSE
63	NTR	Blood	ACAP1	0.02	0.00	blup	437	0.01	6.9e-03	-9.37	7.4	1.3e-13	-0.51	0.04	0.30	FALSE
78	The Cancer Genome Atlas	Colon Adenocarcinoma	GPS2	0.12	0.01	blup	51	0.05	1.2e-03	1.28	-6.9	5.0e-12	0.24	0.01	0.15	FALSE
26	GTEx	Colon Transverse	CHRNB1	0.19	0.01	enet	18	0.11	6.2e-06	1.57	-6.5	8.6e-11	0.47	0.06	0.62	FALSE
62	METSIM	Adipose	NEURL4	0.06	0.00	blup	454	0.01	8.2e-03	0.94	-5.8	5.3e-09	0.31	0.11	0.07	FALSE
77	The Cancer Genome Atlas	Colon Adenocarcinoma	DLG4	0.31	0.01	blup	46	0.07	6.3e-05	-2.33	-5.7	1.3e-08	0.30	0.01	0.08	FALSE
70	YFS	Blood	ACAP1	0.33	0.21	enet	34	0.29	1.1e-96	-3.76	5.4	5.9e-08	-0.31	1.00	0.00	FALSE