[Hub]/) : Traits : Mean time to correctly identify matches :

chr12:48,605,088-50,199,949

Best TWAS P=5.25e-12 · Best GWAS P=4.23e-13 conditioned to 0.00428

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RHEBL1 0.03 0.01 blup 315 0.02 4.4e-03 7.10 5.5 3.6e-08 0.64 0.01 0.94 FALSE
2 GTEx Adipose Subcutaneous LMBR1L 0.12 0.09 lasso 6 0.08 1.9e-07 4.38 -5.3 1.3e-07 -0.54 0.75 0.23 FALSE
3 GTEx Artery Aorta CCDC65 0.19 0.08 enet 7 0.11 1.9e-06 4.11 6.7 2.0e-11 0.82 0.02 0.98 FALSE
4 GTEx Artery Tibial CCDC65 0.14 0.08 enet 39 0.11 7.9e-09 7.25 6.9 5.2e-12 0.80 0.01 0.99 TRUE
5 GTEx Esophagus Mucosa LMBR1L 0.07 0.03 lasso 5 0.04 1.8e-03 5.58 -6.3 2.5e-10 -0.72 0.02 0.96 FALSE
6 GTEx Lung LMBR1L 0.05 0.02 lasso 2 0.00 1.5e-01 5.58 -5.7 1.2e-08 -0.61 0.12 0.33 FALSE
7 GTEx Lung RP11-302B13.5 0.08 0.03 lasso 5 0.03 4.5e-03 -5.05 -5.3 1.2e-07 -0.39 0.79 0.01 FALSE
8 GTEx Muscle Skeletal RP11-386G11.5 0.09 0.07 enet 17 0.08 7.4e-08 6.06 -5.7 1.2e-08 -0.78 0.13 0.87 FALSE
9 GTEx Nerve Tibial LMBR1L 0.08 0.04 lasso 4 0.06 3.1e-05 6.15 -6.0 2.2e-09 -0.65 0.48 0.42 FALSE
10 GTEx Ovary CCDC65 0.38 0.03 lasso 10 0.15 2.0e-04 -0.89 5.4 7.1e-08 0.63 0.06 0.73 FALSE
11 GTEx Skin Sun Exposed Lower leg CCDC65 0.12 0.09 enet 10 0.08 2.6e-07 -4.51 5.2 2.5e-07 0.57 0.89 0.11 FALSE
12 GTEx Testis PRKAG1 0.17 0.11 lasso 5 0.09 1.2e-04 5.58 -6.0 2.6e-09 -0.69 0.11 0.86 FALSE