[Hub]/) : Traits : Mean time to correctly identify matches :

chr12:111,154,626-113,517,494

Best TWAS P=3.18e-12 · Best GWAS P=2.06e-11 conditioned to 0.0652

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ALDH2 0.05 0.11 blup 223 0.10 1.8e-12 -5.0 5.5 4.4e-08 -0.85 0.98 0.02 FALSE
2 CommonMind Brain Pre-frontal Cortex ATXN2 0.02 0.03 enet 8 0.02 4.8e-04 -4.9 5.8 6.2e-09 -0.83 0.08 0.89 FALSE
3 GTEx Adipose Subcutaneous HECTD4 0.06 0.00 enet 15 0.02 1.0e-02 -5.1 5.6 2.3e-08 -0.64 0.16 0.58 FALSE
4 GTEx Adipose Subcutaneous MAPKAPK5-AS1 0.08 0.01 enet 26 0.03 2.1e-03 -6.3 -5.9 3.3e-09 0.92 0.24 0.76 FALSE
5 GTEx Adipose Subcutaneous AC003029.1 0.08 0.07 enet 30 0.05 1.2e-04 -5.1 -5.9 3.2e-09 0.88 0.62 0.38 FALSE
6 GTEx Artery Aorta AC003029.1 0.07 0.01 lasso 7 0.01 5.4e-02 -6.6 -6.1 9.2e-10 0.91 0.07 0.74 FALSE
7 GTEx Artery Tibial ALDH2 0.08 0.09 lasso 2 0.07 2.7e-06 -5.1 5.3 1.1e-07 -0.79 0.86 0.11 FALSE
8 GTEx Artery Tibial HECTD4 0.05 0.02 lasso 3 0.01 3.1e-02 6.2 6.5 1.0e-10 -0.58 0.06 0.69 FALSE
9 GTEx Brain Cerebellar Hemisphere NAA25 0.11 0.02 enet 10 0.00 2.5e-01 -3.4 -5.7 1.3e-08 0.71 0.08 0.44 FALSE
10 GTEx Brain Cerebellum NAA25 0.12 -0.01 lasso 12 0.00 3.0e-01 -3.2 -5.5 2.9e-08 0.73 0.10 0.27 FALSE
11 GTEx Colon Transverse MAPKAPK5-AS1 0.16 0.09 lasso 13 0.06 7.1e-04 -5.0 -5.2 2.4e-07 0.80 0.80 0.03 FALSE
12 GTEx Colon Transverse AC003029.1 0.15 0.09 lasso 12 0.07 2.1e-04 -5.1 -5.2 2.5e-07 0.80 0.80 0.03 FALSE
13 GTEx Esophagus Gastroesophageal Junction AC003029.1 0.06 0.03 lasso 3 0.04 1.9e-02 -5.0 -5.2 1.6e-07 0.80 0.06 0.62 FALSE
14 GTEx Esophagus Mucosa ALDH2 0.05 0.06 lasso 6 0.07 1.7e-05 -5.1 5.4 5.3e-08 -0.83 0.45 0.53 FALSE
15 GTEx Esophagus Muscularis HECTD4 0.06 0.03 lasso 4 0.02 1.8e-02 -5.1 5.8 7.2e-09 -0.82 0.12 0.80 FALSE
16 GTEx Lung ALDH2 0.07 0.01 lasso 10 0.02 5.9e-03 -5.5 5.1 3.0e-07 -0.81 0.25 0.36 FALSE
17 GTEx Nerve Tibial HECTD4 0.05 0.01 enet 6 0.01 3.6e-02 -6.3 6.3 2.2e-10 -0.68 0.03 0.92 FALSE
18 GTEx Nerve Tibial AC003029.1 0.04 0.00 lasso 23 0.00 4.2e-01 -3.5 -5.1 2.8e-07 0.81 0.12 0.34 FALSE
19 GTEx Pituitary RP3-462E2.5 0.15 0.12 lasso 3 0.14 2.3e-04 -5.1 5.9 3.4e-09 -0.91 0.13 0.45 FALSE
20 GTEx Skin Not Sun Exposed Suprapubic ALDH2 0.13 0.18 lasso 9 0.16 5.0e-09 -5.0 5.4 6.5e-08 -0.83 0.85 0.15 FALSE
21 GTEx Skin Not Sun Exposed Suprapubic MAPKAPK5-AS1 0.04 0.00 enet 30 0.00 7.0e-01 -5.1 -5.4 5.5e-08 0.81 0.17 0.30 FALSE
22 GTEx Skin Sun Exposed Lower leg ALDH2 0.10 0.09 enet 13 0.13 6.7e-11 -5.0 6.6 4.3e-11 -0.82 0.55 0.45 FALSE
23 GTEx Skin Sun Exposed Lower leg AC003029.1 0.09 0.10 lasso 2 0.10 8.8e-09 -5.2 -5.2 1.9e-07 0.81 0.99 0.01 FALSE
24 GTEx Stomach TMEM116 0.13 0.03 lasso 7 0.03 1.6e-02 -3.2 -5.5 4.9e-08 0.77 0.05 0.33 FALSE
25 GTEx Testis BRAP 0.06 0.03 enet 13 0.01 8.7e-02 -5.1 -5.5 4.3e-08 0.82 0.25 0.47 FALSE
26 GTEx Thyroid BRAP 0.07 0.02 lasso 7 0.03 1.1e-03 -6.3 -6.5 8.9e-11 0.86 0.19 0.70 FALSE
27 GTEx Thyroid ALDH2 0.06 0.04 lasso 4 0.05 9.7e-05 -6.6 5.7 1.4e-08 -0.93 0.09 0.90 FALSE
28 GTEx Thyroid AC003029.1 0.04 0.05 lasso 3 0.04 8.3e-04 -5.0 -5.2 2.5e-07 0.80 0.44 0.48 FALSE
29 YFS Blood SH2B3 0.05 0.01 enet 22 0.02 3.3e-07 -6.3 7.0 3.2e-12 -0.80 0.04 0.96 TRUE
30 The Cancer Genome Atlas Colon Adenocarcinoma ALDH2 0.07 0.03 lasso 4 0.06 3.9e-04 -3.5 5.4 6.4e-08 -0.69 0.04 0.72 FALSE
31 The Cancer Genome Atlas Brain Lower Grade Glioma ACAD10 0.02 0.02 lasso 3 0.01 7.0e-03 -5.5 -5.6 2.2e-08 0.65 0.02 0.75 FALSE
32 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ERP29 0.11 0.03 blup 25 0.05 5.0e-03 -5.3 -6.1 8.1e-10 0.79 0.02 0.56 FALSE