Best TWAS P=3.68e-11 · Best GWAS P=1.14e-11 conditioned to 0.0787
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | CADM2 | 0.05 | 0.06 | lasso | 10 | 0.06 | 1.3e-09 | -6.0 | -6.6 | 3.7e-11 | 0.65 | 0.68 | 0.32 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | CADM2 | 0.08 | 0.04 | lasso | 4 | 0.05 | 2.1e-06 | -6.6 | -6.1 | 1.3e-09 | 0.89 | 0.04 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CADM2 | 0.05 | 0.03 | lasso | 3 | 0.04 | 5.0e-05 | -6.6 | -6.5 | 5.8e-11 | 0.92 | 0.04 | 0.96 | TRUE |
| 4 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | CADM2 | 0.14 | 0.05 | blup | 339 | 0.09 | 2.7e-04 | -6.8 | -5.7 | 1.5e-08 | 0.84 | 0.03 | 0.87 | FALSE |