[Hub]/) : Traits : Illnesses of father: None of the above (group 1) :

chr15:90,730,363-92,135,418

Best TWAS P=5.74e-14 · Best GWAS P=3.87e-10 conditioned to 0.52

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum FES 0.21 0.09 lasso 5 0.05 1.3e-03 -5.6 5.7 1.1e-08 -0.70 0.10 0.81 FALSE
2 GTEx Artery Tibial FES 0.16 0.04 lasso 5 0.05 4.8e-05 -5.1 6.3 4.0e-10 -0.73 0.09 0.90 FALSE
3 GTEx Cells Transformed fibroblasts FES 0.28 0.17 enet 21 0.20 2.8e-15 -5.6 6.6 5.7e-11 -0.90 0.01 0.99 FALSE
4 GTEx Lung FES 0.24 0.07 lasso 6 0.05 5.1e-05 -5.1 6.2 4.2e-10 -0.79 0.07 0.91 FALSE
5 GTEx Thyroid FES 0.33 0.19 lasso 6 0.18 4.3e-14 -5.5 5.3 1.2e-07 -0.70 0.20 0.80 FALSE
6 METSIM Adipose FES 0.08 0.06 lasso 3 0.05 6.8e-08 -5.1 5.3 1.3e-07 -0.63 0.31 0.69 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma FES 0.06 0.05 blup 46 0.07 7.4e-14 -5.6 6.9 4.5e-12 -0.89 0.01 0.99 FALSE
8 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma FES 0.06 0.02 blup 46 0.02 2.4e-02 -5.6 7.2 7.3e-13 -0.77 0.01 0.80 FALSE
9 The Cancer Genome Atlas Colon Adenocarcinoma FES 0.08 0.07 blup 46 0.06 3.4e-04 -5.8 6.1 8.7e-10 -0.91 0.01 0.98 FALSE
10 The Cancer Genome Atlas Glioblastoma Multiforme FES 0.12 0.06 enet 6 0.06 5.7e-03 -6.0 5.9 3.0e-09 -0.94 0.00 0.92 FALSE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FES 0.06 0.03 blup 46 0.05 5.6e-06 -6.0 5.7 1.4e-08 -0.81 0.01 0.99 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma FES 0.10 0.07 enet 5 0.05 2.8e-06 -6.3 6.0 2.3e-09 -0.99 0.00 1.00 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma FES 0.05 0.04 lasso 2 0.04 2.2e-05 -5.6 6.3 2.4e-10 -0.90 0.01 0.99 FALSE
14 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FES 0.08 0.07 enet 7 0.08 4.2e-09 -5.6 6.2 5.1e-10 -0.82 0.03 0.97 FALSE
15 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma FES 0.13 0.16 lasso 2 0.14 6.1e-10 -5.6 5.6 2.5e-08 -0.71 0.08 0.92 FALSE
16 The Cancer Genome Atlas Prostate Adenocarcinoma FES 0.12 0.09 lasso 5 0.08 4.1e-09 -5.6 6.2 5.0e-10 -0.80 0.06 0.94 FALSE
17 The Cancer Genome Atlas Stomach Adenocarcinoma FES 0.04 0.01 blup 46 0.02 1.7e-02 -6.2 7.5 5.7e-14 -0.78 0.01 0.67 TRUE
18 The Cancer Genome Atlas Testicular Germ Cell Tumors FES 0.32 0.26 lasso 2 0.25 2.0e-09 -5.9 5.9 2.9e-09 -0.72 0.04 0.96 FALSE
19 The Cancer Genome Atlas Thyroid Carcinoma FES 0.30 0.30 lasso 7 0.32 1.3e-31 -5.9 6.5 1.0e-10 -0.84 0.04 0.96 FALSE