Best TWAS P=8.43e-13 · Best GWAS P=2.1e-13 conditioned to 0.0587
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | CADM2 | 0.05 | 0.06 | lasso | 10 | 0.06 | 1.3e-09 | 5.7 | 5.7 | 1.4e-08 | 0.67 | 0.95 | 0.05 | FALSE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CADM2 | 0.06 | 0.00 | blup | 339 | 0.00 | 2.7e-01 | -4.8 | -6.0 | 2.1e-09 | -0.46 | 0.07 | 0.07 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | CADM2 | 0.08 | 0.04 | lasso | 4 | 0.05 | 2.1e-06 | 7.1 | 7.2 | 8.4e-13 | 0.93 | 0.04 | 0.96 | TRUE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CADM2 | 0.05 | 0.03 | lasso | 3 | 0.04 | 5.0e-05 | 7.1 | 6.8 | 8.3e-12 | 0.94 | 0.05 | 0.95 | FALSE |
| 5 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | CADM2 | 0.14 | 0.05 | blup | 339 | 0.09 | 2.7e-04 | 7.2 | 5.5 | 4.6e-08 | 0.84 | 0.05 | 0.80 | FALSE |