Best TWAS P=9.3e-10 · Best GWAS P=9.42e-11 conditioned to 0.0256
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | REV3L | 0.31 | 0.04 | lasso | 11 | 0.12 | 0.00024 | 6.4 | 5.8 | 6.5e-09 | 0.85 | 0.02 | 0.92 | FALSE |
| 2 | GTEx | Brain Hypothalamus | GTF3C6 | 0.32 | 0.04 | lasso | 4 | 0.08 | 0.00678 | 6.4 | -6.1 | 9.3e-10 | -0.90 | 0.02 | 0.83 | TRUE |
| 3 | GTEx | Colon Transverse | RP5-1112D6.4 | 0.11 | 0.10 | lasso | 4 | 0.06 | 0.00071 | 5.2 | 5.3 | 1.3e-07 | 0.81 | 0.35 | 0.16 | FALSE |