Best TWAS P=2.64e-08 · Best GWAS P=2.5e-08 conditioned to 0.122
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Atrial Appendage | EIF4G3 | 0.23 | 0.06 | lasso | 6 | 0.03 | 0.01110 | 4.7 | 5.4 | 5.3e-08 | -0.73 | 0.07 | 0.82 | FALSE |
| 2 | GTEx | Lung | EIF4G3 | 0.08 | 0.03 | lasso | 3 | 0.02 | 0.00573 | -5.5 | 5.6 | 2.6e-08 | -0.86 | 0.04 | 0.95 | TRUE |
| 3 | GTEx | Muscle Skeletal | EIF4G3 | 0.09 | 0.05 | lasso | 6 | 0.03 | 0.00029 | -5.5 | 5.4 | 5.3e-08 | -0.84 | 0.04 | 0.95 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | HP1BP3 | 0.02 | 0.02 | blup | 467 | 0.02 | 0.00405 | -5.5 | -5.4 | 7.2e-08 | 0.88 | 0.04 | 0.90 | FALSE |