Best TWAS P=5.06e-08 · Best GWAS P=4.83e-09 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | PLCL2 | 0.10 | 0.06 | lasso | 5 | 0.09 | 4.5e-07 | 5.9 | 5.4 | 5.1e-08 | 0.95 | 0.01 | 0.99 | TRUE |
2 | METSIM | Adipose | PLCL2 | 0.08 | 0.03 | lasso | 6 | 0.04 | 2.3e-06 | 5.2 | 5.2 | 2.2e-07 | 0.63 | 0.10 | 0.90 | FALSE |