[Hub]/) : Traits : Neuroticism score :

chr2:147,993,969-149,475,737

Best TWAS P=2.16e-12 · Best GWAS P=1.17e-12 conditioned to 0.0113

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Breast Mammary Tissue (Female) ORC4 0.12 0.00 lasso 4 0.00 0.23200 6.8 -6.7 2.7e-11 -0.89 0.03 0.35 FALSE
2 The Cancer Genome Atlas Bladder Urothelial Carcinoma ORC4L 0.07 0.04 blup 37 0.03 0.00061 -5.3 6.3 2.2e-10 0.65 0.05 0.33 FALSE
3 The Cancer Genome Atlas Brain Lower Grade Glioma ORC4L 0.06 0.01 blup 37 0.03 0.00016 6.8 7.0 2.2e-12 0.79 0.01 0.97 TRUE