Best TWAS P=2.06e-09 · Best GWAS P=2.71e-09 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cerebellum | PCGF2 | 0.25 | 0.29 | lasso | 3 | 0.26 | 2.4e-08 | -5.9 | 6.0 | 2.1e-09 | -0.99 | 0.00 | 1.00 | TRUE |
2 | GTEx | Cells Transformed fibroblasts | PCGF2 | 0.34 | 0.28 | lasso | 4 | 0.30 | 3.2e-23 | -5.2 | -5.1 | 2.9e-07 | 0.78 | 0.08 | 0.92 | FALSE |
3 | GTEx | Heart Atrial Appendage | PCGF2 | 0.18 | 0.13 | lasso | 3 | 0.09 | 6.1e-05 | -5.2 | -5.2 | 2.3e-07 | 0.81 | 0.04 | 0.88 | FALSE |
4 | GTEx | Lung | PCGF2 | 0.25 | 0.17 | lasso | 7 | 0.17 | 4.8e-13 | -5.2 | -5.3 | 1.2e-07 | 0.80 | 0.08 | 0.92 | FALSE |
5 | GTEx | Skin Sun Exposed Lower leg | PCGF2 | 0.36 | 0.30 | lasso | 7 | 0.32 | 1.3e-26 | -5.2 | -5.6 | 1.7e-08 | 0.87 | 0.06 | 0.94 | FALSE |
6 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | PCGF2 | 0.13 | 0.06 | blup | 37 | 0.09 | 7.0e-10 | -5.2 | -5.5 | 3.1e-08 | 0.84 | 0.00 | 1.00 | FALSE |
7 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | PCGF2 | 0.24 | 0.15 | lasso | 5 | 0.18 | 2.2e-19 | -5.2 | -5.5 | 5.2e-08 | 0.81 | 0.08 | 0.92 | FALSE |
8 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | PCGF2 | 0.05 | 0.03 | lasso | 3 | 0.04 | 1.0e-05 | -4.4 | -5.3 | 9.5e-08 | 0.79 | 0.01 | 0.98 | FALSE |
9 | The Cancer Genome Atlas | Thyroid Carcinoma | PCGF2 | 0.27 | 0.22 | enet | 9 | 0.25 | 1.4e-24 | -5.2 | -5.1 | 3.1e-07 | 0.77 | 0.08 | 0.92 | FALSE |