[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), Best measure :

chr17:29,482,878-31,275,580

Best TWAS P=1.75e-08 · Best GWAS P=1.91e-08 conditioned to 0.143

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Coronary RHOT1 0.17 0.01 lasso 5 0.00 4.2e-01 4.5 -5.2 1.6e-07 -0.83 0.04 0.36 FALSE
2 GTEx Artery Tibial UTP6 0.07 0.02 lasso 3 0.02 5.9e-03 5.3 -5.3 1.3e-07 -0.85 0.04 0.92 FALSE
3 GTEx Brain Cortex LRRC37B 0.14 0.06 lasso 8 0.02 9.5e-02 5.3 5.1 2.7e-07 0.90 0.04 0.74 FALSE
4 GTEx Breast Mammary Tissue CTC-542B22.2 0.07 0.01 enet 8 0.03 1.7e-02 5.3 5.6 1.8e-08 0.87 0.04 0.87 TRUE
5 GTEx Cells EBV-transformed lymphocytes RHOT1 0.10 0.01 lasso 13 0.01 1.1e-01 5.3 -5.3 1.1e-07 -0.85 0.04 0.71 FALSE
6 GTEx Cells Transformed fibroblasts CTC-542B22.2 0.12 0.03 lasso 6 0.05 2.1e-04 5.6 5.6 2.4e-08 0.96 0.01 0.99 FALSE
7 GTEx Esophagus Mucosa RHOT1 0.07 0.00 lasso 14 0.00 1.5e-01 5.2 -5.4 7.7e-08 -0.88 0.04 0.46 FALSE
8 GTEx Esophagus Mucosa COPRS 0.23 0.21 enet 24 0.19 1.7e-12 5.2 -5.1 3.0e-07 -0.89 0.05 0.95 FALSE
9 GTEx Heart Left Ventricle COPRS 0.08 0.06 lasso 3 0.06 2.4e-04 5.3 -5.3 1.3e-07 -0.91 0.03 0.91 FALSE
10 GTEx Pancreas COPRS 0.14 0.12 lasso 1 0.07 7.2e-04 5.2 -5.2 1.7e-07 -0.89 0.05 0.90 FALSE
11 GTEx Skin Not Sun Exposed Suprapubic COPRS 0.29 0.26 lasso 3 0.24 2.6e-13 5.2 -5.1 2.7e-07 -0.89 0.05 0.94 FALSE
12 GTEx Testis COPRS 0.31 0.26 enet 11 0.28 4.3e-13 5.6 5.6 2.1e-08 0.97 0.01 0.99 FALSE
13 YFS Blood RHOT1 0.04 0.05 blup 330 0.05 7.9e-17 4.8 -5.2 1.5e-07 -0.85 0.15 0.85 FALSE
14 The Cancer Genome Atlas Brain Lower Grade Glioma LRRC37B 0.07 0.10 enet 5 0.09 1.0e-10 5.2 5.2 1.9e-07 0.85 0.02 0.98 FALSE
15 The Cancer Genome Atlas Lung Adenocarcinoma LRRC37B 0.02 0.02 blup 23 0.02 3.5e-03 5.2 5.3 1.3e-07 0.86 0.02 0.85 FALSE
16 The Cancer Genome Atlas Prostate Adenocarcinoma C17orf79 0.07 0.04 lasso 2 0.03 1.5e-04 5.6 -5.6 1.8e-08 -0.99 0.00 1.00 FALSE