Best TWAS P=7.36e-09 · Best GWAS P=1.26e-10 conditioned to 0.00484
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | ANGPTL1 | 0.14 | 0.08 | lasso | 3 | 0.07 | 7.4e-05 | 6.3 | 5.8 | 7.4e-09 | 0.90 | 0.01 | 0.97 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | ANGPTL1 | 0.07 | 0.04 | blup | 42 | 0.05 | 2.3e-06 | -3.5 | 5.5 | 3.8e-08 | 0.74 | 0.05 | 0.92 | FALSE |