[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), Best measure : ← →

chr1:149,672,809-151,659,071

Best TWAS P=1.43e-09 · Best GWAS P=1.58e-10 conditioned to 0.00562

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Esophagus Muscularis	CTSS	0.05	0.04	enet	12	0.06	1.2e-04	5.0	6.1	1.4e-09	0.71	0.11	0.83	TRUE
13	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PPIAL4C	0.06	0.03	enet	6	0.04	1.3e-04	-4.4	-5.6	1.8e-08	-0.03	0.00	0.13	TRUE
16	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	CTSS	0.16	0.08	enet	8	0.07	1.6e-05	-4.6	5.8	6.5e-09	0.69	0.01	0.96	FALSE
11	GTEx	Thyroid	ARNT	0.08	0.10	lasso	10	0.10	7.8e-08	-5.3	5.7	1.2e-08	0.91	0.02	0.98	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CERS2	0.04	0.03	bslmm	307	0.02	1.7e-03	4.9	5.4	7.4e-08	0.71	0.43	0.39	FALSE
5	GTEx	Breast Mammary Tissue (Male)	RP11-54A4.2	0.07	0.01	enet	2	0.03	7.4e-02	-5.2	-5.4	8.4e-08	-0.74	0.04	0.25	FALSE
8	GTEx	Muscle Skeletal	CTSS	0.04	0.01	enet	13	0.03	1.4e-03	6.0	5.4	8.7e-08	0.81	0.06	0.89	FALSE
7	GTEx	Heart Atrial Appendage	CTSK	0.13	0.02	enet	8	0.05	2.1e-03	3.3	-5.3	9.9e-08	-0.70	0.05	0.87	FALSE
2	GTEx	Brain Cortex	CTSS	0.17	0.06	lasso	6	0.04	2.7e-02	5.9	5.3	1.1e-07	0.75	0.03	0.76	FALSE
14	The Cancer Genome Atlas	Breast Invasive Carcinoma	CTSS	0.02	0.01	enet	4	0.01	2.8e-03	3.8	5.3	1.2e-07	0.73	0.03	0.84	FALSE
3	GTEx	Brain Hippocampus	ARNT	0.14	0.09	enet	14	0.08	5.3e-03	5.3	5.3	1.4e-07	0.84	0.02	0.77	FALSE
9	GTEx	Pituitary	CTSK	0.14	0.14	lasso	2	0.06	1.6e-02	5.3	5.2	1.9e-07	0.74	0.06	0.62	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CTSS	0.04	0.01	enet	4	0.03	4.7e-04	5.0	5.2	1.9e-07	0.67	0.03	0.92	FALSE
12	NTR	Blood	CTSK	0.03	0.02	enet	22	0.02	8.1e-08	5.0	5.2	2.1e-07	0.59	0.68	0.32	FALSE
10	GTEx	Skin Not Sun Exposed Suprapubic	ANXA9	0.11	0.12	lasso	2	0.13	2.0e-07	-4.6	5.2	2.2e-07	0.58	0.44	0.32	FALSE
4	GTEx	Brain Hypothalamus	RP11-316M1.12	0.14	0.03	lasso	6	0.02	9.9e-02	4.9	-5.1	2.6e-07	-0.81	0.10	0.11	FALSE