TWAS
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Traits
:
Forced expiratory volume in 1-second (FEV1), Best measure
:
←
→
chr2:218,300,530-219,878,756
Best TWAS P=2.91e-10 · Best GWAS P=2.28e-11 conditioned to 4.98e-08
218.4M
218.6M
218.8M
219M
219.2M
219.4M
219.6M
219.8M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Adipose Visceral Omentum
PNKD
0.11
0
enet
31
0.00
0.2260
-3.4
6.3
2.9e-10
-0.22
0.14
0.05
TRUE
2
METSIM
Adipose
CXCR2
0.04
0
blup
436
0.02
0.0011
-3.7
5.2
1.6e-07
0.08
0.28
0.03
FALSE