[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), Best measure :

chr2:177,559,549-179,175,022

Best TWAS P=5.67e-11 · Best GWAS P=1.07e-08 conditioned to 0.574

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Nucleus accumbens basal ganglia AC073834.3 0.16 0.01 enet 33 0.05 2.1e-02 -5.4 -6.1 1.2e-09 0.69 0.04 0.90 FALSE
2 GTEx Breast Mammary Tissue AC073834.3 0.13 0.12 lasso 4 0.08 4.9e-05 -5.2 -5.3 1.2e-07 0.97 0.04 0.96 FALSE
3 GTEx Breast Mammary Tissue (Male) AC073834.3 0.22 0.13 enet 18 0.07 8.7e-03 -3.2 -5.3 1.4e-07 0.88 0.05 0.84 FALSE
4 GTEx Cells Transformed fibroblasts AC073834.3 0.13 0.16 lasso 2 0.16 6.7e-12 -5.0 -5.2 2.0e-07 0.75 0.24 0.75 FALSE
5 GTEx Pituitary AC073834.3 0.18 0.18 lasso 7 0.12 7.2e-04 -5.6 -5.7 1.1e-08 0.97 0.04 0.88 FALSE
6 GTEx Spleen AC073834.3 0.17 0.08 enet 22 0.08 3.6e-03 -5.4 -6.5 5.7e-11 0.82 0.04 0.86 TRUE
7 YFS Blood AGPS 0.02 0.01 bslmm 504 0.01 6.5e-05 -5.5 5.4 8.3e-08 -0.76 0.04 0.91 FALSE
8 The Cancer Genome Atlas Stomach Adenocarcinoma LOC100130691 0.15 0.07 blup 70 0.12 2.5e-09 -5.5 -5.2 1.9e-07 0.69 0.03 0.97 FALSE