Best TWAS P=5.67e-11 · Best GWAS P=1.07e-08 conditioned to 0.574
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Nucleus accumbens basal ganglia | AC073834.3 | 0.16 | 0.01 | enet | 33 | 0.05 | 2.1e-02 | -5.4 | -6.1 | 1.2e-09 | 0.69 | 0.04 | 0.90 | FALSE |
2 | GTEx | Breast Mammary Tissue | AC073834.3 | 0.13 | 0.12 | lasso | 4 | 0.08 | 4.9e-05 | -5.2 | -5.3 | 1.2e-07 | 0.97 | 0.04 | 0.96 | FALSE |
3 | GTEx | Breast Mammary Tissue (Male) | AC073834.3 | 0.22 | 0.13 | enet | 18 | 0.07 | 8.7e-03 | -3.2 | -5.3 | 1.4e-07 | 0.88 | 0.05 | 0.84 | FALSE |
4 | GTEx | Cells Transformed fibroblasts | AC073834.3 | 0.13 | 0.16 | lasso | 2 | 0.16 | 6.7e-12 | -5.0 | -5.2 | 2.0e-07 | 0.75 | 0.24 | 0.75 | FALSE |
5 | GTEx | Pituitary | AC073834.3 | 0.18 | 0.18 | lasso | 7 | 0.12 | 7.2e-04 | -5.6 | -5.7 | 1.1e-08 | 0.97 | 0.04 | 0.88 | FALSE |
6 | GTEx | Spleen | AC073834.3 | 0.17 | 0.08 | enet | 22 | 0.08 | 3.6e-03 | -5.4 | -6.5 | 5.7e-11 | 0.82 | 0.04 | 0.86 | TRUE |
7 | YFS | Blood | AGPS | 0.02 | 0.01 | bslmm | 504 | 0.01 | 6.5e-05 | -5.5 | 5.4 | 8.3e-08 | -0.76 | 0.04 | 0.91 | FALSE |
8 | The Cancer Genome Atlas | Stomach Adenocarcinoma | LOC100130691 | 0.15 | 0.07 | blup | 70 | 0.12 | 2.5e-09 | -5.5 | -5.2 | 1.9e-07 | 0.69 | 0.03 | 0.97 | FALSE |