Best TWAS P=5.18e-09 · Best GWAS P=3.16e-09 conditioned to 0.00491
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | YFS | Blood | H1FX | 0.02 | 0.01 | lasso | 3 | 0.01 | 1.4e-03 | -5.2 | 5.3 | 8.7e-08 | -0.84 | 0.04 | 0.75 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | H1FX | 0.02 | 0.02 | lasso | 5 | 0.03 | 6.5e-07 | 3.6 | 5.8 | 8.3e-09 | -0.62 | 0.09 | 0.88 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | H1FX | 0.02 | 0.00 | blup | 36 | 0.00 | 5.1e-01 | -5.9 | 5.8 | 5.2e-09 | -0.65 | 0.01 | 0.60 | TRUE |