TWAS
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Traits
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Traits
:
Forced expiratory volume in 1-second (FEV1), Best measure
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chr4:686,563-2,058,475
Best TWAS P=5.92e-08 · Best GWAS P=2.71e-06 conditioned to 0.174
0.8M
1M
1.2M
1.4M
1.6M
1.8M
2M
0
1
2
3
4
5
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Brain Cortex
CRIPAK
0.34
0.10
lasso
6
0.18
9.5e-06
-4.1
-5.4
5.9e-08
0.68
0.02
0.49
TRUE
1
GTEx
Adipose Visceral Omentum
CRIPAK
0.47
0.24
lasso
12
0.31
1.3e-16
-4.1
-5.3
1.3e-07
0.76
0.03
0.84
FALSE
3
GTEx
Heart Left Ventricle
CRIPAK
0.19
0.05
enet
24
0.21
3.4e-11
-4.1
-5.1
2.8e-07
0.65
0.05
0.53
FALSE