[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), Best measure : ← →

chr5:156,009,720-157,697,754

Best TWAS P=1.12e-15 · Best GWAS P=1.77e-13 conditioned to 0.000368

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ADAM19	0.08	0.02	blup	159	0.03	5.3e-04	-5.9	-8.0	1.1e-15	-0.55	0.04	0.78	TRUE
8	GTEx	Muscle Skeletal	ADAM19	0.06	0.02	lasso	4	0.01	1.5e-02	-7.2	-7.8	9.5e-15	-0.47	0.01	0.98	FALSE
12	GTEx	Skin Sun Exposed Lower leg	ADAM19	0.07	0.04	lasso	6	0.06	1.2e-05	-5.9	-7.7	1.2e-14	-0.45	0.02	0.97	FALSE
17	The Cancer Genome Atlas	Lung Adenocarcinoma	ADAM19	0.09	0.03	lasso	4	0.05	2.4e-06	-7.2	-7.5	4.4e-14	-0.54	0.01	0.98	FALSE
15	METSIM	Adipose	ADAM19	0.08	0.07	lasso	9	0.07	2.5e-10	-7.2	-7.2	5.6e-13	-0.52	0.01	0.99	FALSE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	ADAM19	0.05	0.01	blup	159	0.03	9.5e-04	3.8	-7.2	5.8e-13	-0.44	0.06	0.19	FALSE
2	GTEx	Breast Mammary Tissue	ADAM19	0.11	0.10	lasso	1	0.06	3.6e-04	-7.2	-7.2	5.9e-13	-0.52	0.01	0.98	FALSE
1	GTEx	Adipose Subcutaneous	ADAM19	0.09	0.08	lasso	6	0.05	5.6e-05	-7.2	-7.2	6.7e-13	-0.53	0.01	0.99	FALSE
13	GTEx	Testis	ADAM19	0.16	0.00	enet	17	-0.01	6.7e-01	-4.5	-7.2	7.9e-13	-0.44	0.03	0.86	FALSE
4	GTEx	Breast Mammary Tissue (Female)	ADAM19	0.11	0.14	lasso	6	0.10	5.1e-04	-7.2	-7.0	2.0e-12	-0.51	0.01	0.88	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	ADAM19	0.07	0.00	blup	159	0.02	2.0e-03	2.6	-7.0	2.5e-12	-0.49	0.15	0.17	FALSE
11	GTEx	Skin Not Sun Exposed Suprapubic	ADAM19	0.10	0.01	lasso	4	0.08	5.2e-05	-4.8	-6.9	4.0e-12	-0.40	0.02	0.97	FALSE
5	GTEx	Cells Transformed fibroblasts	ADAM19	0.16	0.02	enet	17	0.06	3.0e-05	3.7	-6.8	1.1e-11	-0.40	0.09	0.90	FALSE
7	GTEx	Esophagus Mucosa	ADAM19	0.14	0.03	enet	19	0.09	2.4e-06	2.7	-6.2	5.7e-10	-0.28	0.08	0.86	FALSE
10	GTEx	Ovary	ADAM19	0.32	0.11	lasso	9	0.08	6.5e-03	-4.0	-5.9	4.5e-09	-0.37	0.06	0.66	FALSE
3	GTEx	Breast Mammary Tissue (Male)	ADAM19	0.08	0.03	lasso	1	-0.01	7.7e-01	5.7	-5.7	1.0e-08	-0.39	0.05	0.21	FALSE
9	GTEx	Nerve Tibial	ADAM19	0.34	0.16	enet	45	0.30	1.2e-21	-4.6	-5.6	2.3e-08	-0.38	0.01	0.99	FALSE
6	GTEx	Colon Sigmoid	CYFIP2	0.24	0.26	lasso	5	0.24	6.2e-09	-5.5	-5.6	2.5e-08	-0.26	0.98	0.01	FALSE
14	GTEx	Whole Blood	ADAM19	0.12	0.07	enet	20	0.07	9.8e-07	-4.6	-5.5	5.2e-08	-0.41	0.92	0.08	FALSE