Best TWAS P=7.18e-09 · Best GWAS P=5.54e-09 conditioned to 0.0319
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | RAB24 | 0.14 | 0.06 | enet | 14 | 0.09 | 4.2e-11 | 4.9 | 5.5 | 3.7e-08 | 0.71 | 0.10 | 0.90 | TRUE |
| 2 | GTEx | Artery Tibial | RAB24 | 0.18 | 0.09 | lasso | 3 | 0.07 | 2.3e-06 | 4.9 | 5.3 | 1.2e-07 | 0.77 | 0.05 | 0.95 | FALSE |
| 3 | GTEx | Heart Atrial Appendage | MXD3 | 0.33 | 0.15 | enet | 24 | 0.16 | 1.5e-07 | 2.2 | 5.8 | 7.2e-09 | 0.29 | 0.80 | 0.02 | TRUE |
| 4 | GTEx | Nerve Tibial | RAB24 | 0.27 | 0.08 | enet | 32 | 0.17 | 6.3e-12 | 3.6 | 5.6 | 2.1e-08 | 0.47 | 0.12 | 0.86 | FALSE |
| 5 | The Cancer Genome Atlas | Colon Adenocarcinoma | RAB24 | 0.08 | 0.04 | enet | 7 | 0.06 | 3.4e-04 | -3.9 | 5.7 | 1.3e-08 | 0.54 | 0.01 | 0.27 | FALSE |